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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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On Sale
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Custom Synthesis
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Name Index V
Vipadenant
(Catalog# : 010436, Cas# :
442908-10-3
)
Vipadenant is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69
Vatalanib
(Catalog# : 010434, Cas# :
212141-54-3
)
Vatalanib free base is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent aga
VE-821
(Catalog# : 122817, Cas# :
1232410-49-9
)
VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13
VU 0364439
(Catalog# : 122401, Cas# :
1246086-78-1
)
VU 0364439 is a mGlu4 positive allosteric modulator, with EC50 of 19.8 nM.
Vicriviroc Malate
(Catalog# : 122219, Cas# :
541503-81-5
)
Vicriviroc Malate is a potent inhibitor of HIV-1 entry into target cells, with a mean
Vilazodone
(Catalog# : 122208, Cas# :
163521-12-8
)
Vilazodone is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A rece
VU 0357121
(Catalog# : 122206, Cas# :
433967-28-3
)
VU0357121 is a novel positive and highly selective allosteric modulator (PAM) of mGlu
Vilazodone Hydrochloride
(Catalog# : 121808, Cas# :
163521-08-2
)
Vilazodone Hcl is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A
VX-11e
(Catalog# : 120806, Cas# :
896720-20-0
)
Coming soon!
VR23
(Catalog# : 120423, Cas# :
1624602-30-7
)
VR23 is a small molecule that potently inhibited the activities of trypsin-like prote
Vacquinol-1
(Catalog# : 111906, Cas# :
5428-80-8
)
Vacquinols are a new class of quinine-derivatives that stimulate death in glioblastom
VPS34-IN1
(Catalog# : 111016, Cas# :
1383716-33-3
)
VPS34-IN1 is a selective inhibitor of Vps34.
VRT-1353385
(Catalog# : 101912, Cas# :
1616113-45-1
)
Coming soon!
VX-809(Lumacaftor)
(Catalog# : 92219, Cas# :
936727-05-8
)
From Wikipedia, the free encyclopediaLumacaftor (USAN, codenamed VX-809) is an experi
VRT752271
(Catalog# : 92212, Cas# :
869886-67-9
)
Coming soon!
Vanoxerine
(Catalog# : 61001, Cas# :
67469-69-6
)
Vanoxerine (GBR12909) is a potent and selective DRI (Dopamine reuptake inhibitor).
Vidofludimus
(Catalog# : 60201, Cas# :
717824-30-1
)
Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH;
Venetoclax(ABT-199)
(Catalog# : 60101, Cas# :
1257044-40-8
)
Venetoclax, formerly known as ABT-199(GDC-0199), is a Bcl-2-selective inhibitor with
Vandetanib
(Catalog# : 52821, Cas# :
443913-73-3
)
Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM.
Vortioxetine hydrobromide
(Catalog# : 52716, Cas# :
960203-27-4
)
Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A
Vemurafenib (PLX4032, RG7204)
(Catalog# : 52589, Cas# :
918504-65-1
)
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor ofB-RafV600EwithIC50of
VS-5584
(Catalog# : 52530, Cas# :
1246560-33-7
)
VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3K///
VGX-1027
(Catalog# : 52316, Cas# :
6501-72-0
)
VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory prope
Vismodegib(GDC-0449)
(Catalog# : 52307, Cas# :
879085-55-9
)
Vismodegib (GDC-0449) is a potent, novel and specifichedgehoginhibitor withIC50of 3 n
VX-680(Tozasertib,MK-0457)
(Catalog# : 52005, Cas# :
639089-54-6
)
VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A wit
VE-822 ( Berzosertib )
(Catalog# : 51607, Cas# :
1232416-25-9
)
VE-822(Berzosertib), an analogue of VE-821 with increased potency and selectivity aga
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the