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首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
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JAK/STAT
MAPK
Cytoskeletal Signaling
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Cas号索引 1
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Cas号索引 1
114985-63-6 | 1-acetyl-5-nitro-3H-indol-2-one
(Catalog# : 2062319)
1035299-32-3 | 8-Acetyl-5-(benzyloxy)-2H-benzo[b][1,4]oxazin-3(4H)-one
(Catalog# : 2062311)
113305-94-5 | 2-Amino-5-cyanopyrazine
(Catalog# : 2062307)
1452226-14-0 | 5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxylic acid
(Catalog# : 2062025)
1056901-64-4 | AT13148 intermediate(N1)
(Catalog# : 2062009)
177036-94-1 | Ambrisentan
(Catalog# : 2061308)
Ambrisentan, also known as BSF-208075 and LU-208075, is a drug indicated for use in t
186141-75-3 | A134974
(Catalog# : 204605)
A134974 is a bioactive chemical.
1375557-33-7 | A-1293201
(Catalog# : 204604)
A-1293201 is a potent and selective NAMPT inhibitor.
1219624-62-0 | A-1048400
(Catalog# : 204602)
A-1048400 is a potent and selective N-type and T-type calcium channel blocker.
1821-13-2 | A-1062
(Catalog# : 204601)
A-1062 is a resolvase-binding inhibitor. A1062 inhibits resolvase binding to the res
1103522-45-7 | Aprocitentan
(Catalog# : 112191)
Aprocitentan is an orally active, dual endothelin (ET) receptor antagonist developed
1838651-58-3 | ACT-709478
(Catalog# : 193288)
ACT-709478是一种强效、选择性的T型钙通道阻滞剂,是治疗全身性癫
1893415-00-3 | AZD9567
(Catalog# : 193254)
AZD9567是一种口服分化非甾体选择性糖皮质激素受体调节剂(SGRM)。
133825-81-7 | ATR-101盐酸盐
(Catalog# : 193208)
ATR-101,也被称为PD-132301 (游离)或PD-132301-2 (盐酸盐),正在临床开发
1613710-01-2 | ARN-3236
(Catalog# : 193192)
ARN-3236是一种强效、口服活性和选择性的SIK2抑制剂。在攻击- 3236抑
1373625-34-3 | ARN 077
(Catalog# : 193134)
ARN 077是一种强效选择性N -乙酰乙醇胺酸酰胺酶(NAAA)抑制剂,IC50为
156053-89-3 | Alvimopan
(Catalog# : 19382)
Alvimopan,也称为HSDB-7704和LY246736, 是一种作为一个次要地行动的μ-
1622902-68-4 | Abrocitinib
(Catalog# : 19381)
Abrocitinib(PF-04965842)是Pifzer研发的是一种Janus激酶抑制剂药物,目
1312782-34-5 | AA26-9
(Catalog# : 19372)
AA26-9是一种高效广谱丝氨酸水解酶抑制剂。AA26 -9抑制酶来源于丝
118292-41-4 | AGN-190299
(Catalog# : 19316)
Tazarotene是一种视黄醇类前体药物,通过在动物和人体内的快速脱
1126084-37-4 | ASP9521
(Catalog# : 19312)
ASP9521是日常的,选择性,口服生物利用率17β-羟甾类脱氢酶的抑制
1345614-59-6 | AM095钠
(Catalog# : 191251)
AM095是一个强有力的LPA1受体拮抗剂,因为它抑制GTPγS绑定中国仓鼠
1036404-17-7 | ARRY-797 (ARRY-371797)
(Catalog# : 191112)
ARRY-797(CAS1036404-17-7) is an oral, selective p38 mitogen-activated protein kinase
1557267-42-1 | 艾维替尼
(Catalog# : 19141)
艾维替尼,又称AC0010和Avitinib,是酪氨酸激酶抑制剂,抗肿瘤药物
1041852-85-0 | AZD7507
(Catalog# : 1812294)
AZD7507是一种有效的选择性CSF-1R抑制剂(32 nM 细胞活性), AZD7507被认
1704801-24-0 | AX-024盐酸盐
(Catalog# : 181254)
AX-024是一种口服的TCR-Nck相互作用抑制剂,选择性地抑制TCR-触发的
148741-30-4 | AG 879
(Catalog# : 1811303)
AG-879是一种酪氨酸磷酸化抑制剂复合物,可抑制PC-12细胞中依赖神
1146699-66-2 | Avagacestat
(Catalog# : 1811283)
Avagacestat,也称为BMS- 708163是一种口服GSI用于选择性抑制Aβ合成,目
1360460-82-7 | Anlotinib HCl ( AL-3818 )
(Catalog# : 1811211)
Anlotinib也被称为AL3818,是一种受体酪氨酸激酶(RTK)抑制剂,具有潜
1240299-33-5 | AZD-3514
(Catalog# : 1810251)
AZD-3514是一种具有潜在抗癌活性的雄激素受体下调因子。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag