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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Aldehydes
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
Fluorides
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Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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联系我们
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Cas号索引 1
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Cas号索引 1
1027847-67-1 | AMG-009
(Catalog# : 17987)
AMG 009是一种口服活性小分子CRTH2受体(趋化受体的同源分子表达在
1426136-04-0 | 5-氨基-2-氟-4-甲基苯腈
(Catalog# : 1781603)
5-氨基-2-氟-4-甲基苯腈,5-amino-2-fluoro-4-methylbenzonitrile
1434141-67-9 | 2-azaspiro[3.5]nonan-7-ol hydrochloride
(Catalog# : 1781602)
2-azaspiro[3.5]nonan-7-ol hydrochloride
1231929-97-7 | Abemaciclib ( LY2835219)
(Catalog# : 178141)
Abemaciclib,也被称为LY2835219,可口服细胞周期依赖性激酶(CDK)抑制
1609281-86-8 | AZD3264
(Catalog# : 178910)
AZD3264是一种新型的小分子IKK2抑制剂。IKK2作为IB激酶的蛋白质亚基
1240308-45-5 | A-971432
(Catalog# : 178816)
A - 971432对S1P5具有高度选择性,在临床前口服剂量后,显露出良好
1221443-94-2 | A-1165442
(Catalog# : 20178812)
A-1165442是一种中性温度具有止痛功效的瞬时受体电位香草酸亚型1
1375466-18-4 | ACY-775
(Catalog# : 77821)
ACY-775是一种组蛋白去乙酰化酶6(HDAC6)选择性抑制剂。
1001404-83-6 | AAI-101
(Catalog# : 1773101)
AAI101(AAI101)是一种新型的增谱-乳酸酶抑制剂。AAI101(AAI101)与头孢吡
1196509-60-0 | AZD-7594
(Catalog# : 17022812)
AZD-7594,也叫AZ13189620,是一种吸入选择性糖皮质激素受体(GCCR)调制
1227163-56-5 | AZD3839
(Catalog# : 17022710)
AZD3839是一种有效的选择性BACE1抑制剂。AZD3839是治疗阿尔茨海默病
1668553-26-1 | A-1210477
(Catalog# : 17022404)
A-1210477是一种有效、选择性的MCL-1抑制剂。
1383982-64-6 | AZD3293 (LY3314814)
(Catalog# : 17021318)
AZD3293,也称为LY3314814是一种口服β-分泌酶1裂解酶(BACE)抑制剂。
1620576-64-8 | AZD-8835
(Catalog# : 102703)
AZD8835 is a potent and selective inhibitor ofPI3KαandPI3KδwithIC50s of 6.2 and 5.7
1173900-37-2 | AZD6482 (S-isomer)
(Catalog# : 17011901)
AZD6482是强有力的,选择性和ATP竞争PI3K抑制剂(IC50为0.01μm)。
1472624-85-3 | 7ACC2
(Catalog# : 17011302)
7ACC2是一种有效的MCT抑制剂。
1174043-16-3 | AZD-2461
(Catalog# : 16122863)
AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. A
1557268-88-8 | Avitinib maleate
(Catalog# : 16122862)
Avitinib is an orally available, irreversible, epidermal growth factor receptor (EGFR
1192491-61-4 | Avibactam sodium
(Catalog# : 16122861)
Avibactam is a non--lactam -lactamase inhibitor antibiotic, which is a new drug appli
141396-28-3 | Argatroban
(Catalog# : 16122858)
Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was ap
1442684-77-6 | AM-2394
(Catalog# : 16122855)
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phos
1047645-82-8 | Afuresertib HCl
(Catalog# : 161227116)
Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the ser
1375465-91-0 | ACY-738
(Catalog# : 161227114)
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability
182167-02-8 | Acolbifene
(Catalog# : 161227113)
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modu
1762-34-1 | Abametapir
(Catalog# : 161227111)
Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metallopro
106566-58-9 | AS101
(Catalog# : 161227106)
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1bet
1420477-60-6 | ACP-196
(Catalog# : 16122783)
Acalabrutinib is a selective second-generation Brutons tyrosine kinase (BTK) inhibito
1527503-11-2 | A-366
(Catalog# : 16122743)
A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor wi
1821428-35-6 | AZD0156
(Catalog# : 16122713)
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/rad
1189904-01-5 | Acetazolamide D3
(Catalog# : 6111513)
Acetazolamide D3 is deuterium labeled Acetazolamide, which is a potent carbonic anhyd
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag