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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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技术服务
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
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产品名字索引 A
AS 602801
(Catalog# : 011913, Cas# :
848344-36-5
)
AS 602801 is a novel, orally active inhibitor of JNK.
AMG232
(Catalog# : 011911, Cas# :
1352066-68-2
)
AMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.
Afdx 384
(Catalog# : 011905, Cas# :
118290-27-0
)
Coming soon!
Avoralstat
(Catalog# : 011813, Cas# :
918407-35-9
)
Avoralstat(前身为BCX4161)是一种有效的小分子口服血浆激肽释放酶
AMG-337
(Catalog# : 01181, Cas# :
1173699-31-4
)
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase in
Afuresertib
(Catalog# : 011811, Cas# :
1047644-62-1
)
Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib i
AMG 900
(Catalog# : 011803, Cas# :
945595-80-2
)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
APTO-253
(Catalog# : 011802, Cas# :
1422731-37-0
)
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor
AC-55541
(Catalog# : 011302, Cas# :
916170-19-9
)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
AZ 628
(Catalog# : 011120, Cas# :
878739-06-1
)
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM
AZD-5582
(Catalog# : 011117, Cas# :
1258392-53-8
)
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI moti
Arbidol hydrochloride
(Catalog# : 011111, Cas# :
131707-23-8
)
Arbidol is an broad-spectrum antiviral chemical agent which can inhibit cell entry of
APY29
(Catalog# : 011108, Cas# :
1216665-49-4
)
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 2
AMG-47a
(Catalog# : 011107, Cas# :
882663-88-9
)
AMG-47a is a potent inhibitor of Lck and T cell proliferation.
ARQ-736
(Catalog# : 011104, Cas# :
1228237-57-7
)
ARQ 736 is a potent and selective BRAF inhibitor.
AZD4547
(Catalog# : 010820, Cas# :
1035270-39-3
)
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2
AZD-1480
(Catalog# : 010816, Cas# :
935666-88-9
)
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity a
AZD8330
(Catalog# : 010809, Cas# :
869357-68-6
)
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 n
AS703026
(Catalog# : 010808, Cas# :
1236699-92-5
)
AS703026 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2)
AZ505
(Catalog# : 010803, Cas# :
1035227-43-0
)
AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=
AG-L-59687
(Catalog# : 010428, Cas# :
793035-88-8
)
Coming soon!
AG1024
(Catalog# : 010422, Cas# :
65678-07-1
)
AG-1024 inhibits IGF-1R autophosphorylation with IC50 of 7 M, less potent to IR with
Almotriptan
(Catalog# : 010418, Cas# :
154323-57-6
)
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.
AM630
(Catalog# : 010410, Cas# :
164178-33-0
)
AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM; > 150 fold selectivity o
AZD-8055
(Catalog# : 123019, Cas# :
1009298-09-2
)
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential a
Amuvatinib
(Catalog# : 123016, Cas# :
850879-09-3
)
Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC5
AR-42
(Catalog# : 123009, Cas# :
935881-37-1
)
AR-42 is a novel, oral cancer therapy currently in early clinical development.
A-966492
(Catalog# : 123006, Cas# :
934162-61-5
)
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 n
AMG 487
(Catalog# : 122942, Cas# :
473719-41-4
)
AMG 487 is a small molecule antagonist of the chemokine receptor CXCR3.
Atosiban acetate
(Catalog# : 122931, Cas# :
90779-69-4
)
Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag