武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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others
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Anilines
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
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Indoles and Oxindoles
Iodos
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 P
PF-06882961
(Catalog# : 21251, Cas# :
2230198-02-2
)
PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 r
3PO
(Catalog# : 21227, Cas# :
18550-98-6
)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
PF-06802861 ( ARRY 371797 ; ARRY-797 )
(Catalog# : 2073108, Cas# :
1034189-82-6
)
ARRY 797(也称为ARRY 371797或PF 06802861)是一种具有口服活性,选择性
PF-04745637
(Catalog# : 2071623, Cas# :
1917294-46-2
)
PF-04745637 is a TRPV1 antagonist.
Pepstatin
(Catalog# : 2071607, Cas# :
26305-03-3
)
Pepstatin inhibits the aspartic protease endothiapepsin.
PF-477736
(Catalog# : 2071540, Cas# :
952021-60-2
)
PF-477736, also known as PF-00477736, is a potent CHK1 inhibitor with potential chemo
PF-06869206
(Catalog# : 2071506, Cas# :
2227425-05-8
)
PF-06869206 is an Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Co
Pimodivir ( VX-787 )
(Catalog# : 2071401, Cas# :
1629869-44-8
)
Pimodivir (VX-787) 是一种可口服的甲型流感病毒聚合酶抑制剂,通过
p-Aminophenol sulfate
(Catalog# : 2062201, Cas# :
85278-22-4
)
3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
(Catalog# : 2062020, Cas# :
26033-20-5
)
Preladenant
(Catalog# : 2061707, Cas# :
377727-87-2
)
Preladenant, also known as SCH 420814, is a potent and selective antagonist at the ad
Paquinimod
(Catalog# : 2061706, Cas# :
248282-01-1
)
Paquinimod, also known as ABR‑215757, is a S100A9 inhibitor preventing S100A9 bindi
PDM-2
(Catalog# : 2061301, Cas# :
688348-25-6
)
PDM-2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon r
PU-WS13
(Catalog# : 206701, Cas# :
1454619-14-7
)
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-
吡啶-2,6-二甲醛
(Catalog# : S-204148, Cas# :
5431-44-7
)
1-((1aR,6r,10bS)-1,1-二氟-1,1a,6,10b-四氢二苯并[a,e]环丙[c][7]环壬-6-基)哌嗪盐酸盐
(Catalog# : S-204141, Cas# :
312905-21-8
)
PZ-2891
(Catalog# : 193282, Cas# :
2170608-82-7
)
PZ-2891是一种强效的、选择性的、口服活性泛酸激酶(PANK)调制剂,
PTI-428(PTI428)
(Catalog# : 31619, Cas# :
1953130-87-4
)
PTI-428是一种研究性CFTR放大器,开发用于治疗CFTR基因中发生F508del
PF-05085727
(Catalog# : 1932011, Cas# :
1415637-72-7
)
PF-05085727是一种强效、选择性和脑穿透性磷酸二酯酶2A抑制剂。
Petesicatib
(Catalog# : 193206, Cas# :
1252637-35-6
)
Petesicatib是一种组织蛋白酶抑制剂的候选药物。
Pyridone 6
(Catalog# : 193204, Cas# :
457081-03-7
)
吡啶酮6,也被称为CMP 6或JAK抑制剂I,是一种pan-janus-激活的激酶抑
Pretomanid
(Catalog# : 193110, Cas# :
187235-37-6
)
Pretomanid,也被称为PA-824,一种生物还原药物。PA-824具有较强的体
PF-4136309
(Catalog# : 192282, Cas# :
1341224-83-6
)
PF-4136309,又称INCB8761,是一种口服的人趋化因子受体2 (CCR2)拮抗剂
帕利伐米
(Catalog# : 192272, Cas# :
31645-39-3
)
帕利伐米,又名ZIO201,是一种具有潜在抗肿瘤活性的合成芥菜化合
PF-06873600
(Catalog# : 191145, Cas# :
2185857-97-8
)
PF-06873600是一种口服生物利用的细胞周期蛋白依赖性激酶(CDK)抑制
PF04418948
(Catalog# : 191141, Cas# :
1078166-57-0
)
PF-04418948是一种新型高效选择性前列腺素EP2受体拮抗剂。
PF74
(Catalog# : 1812253, Cas# :
1352879-65-2
)
PF-3450074,又称PF74,是一种针对HIV衣壳蛋白的HIV-1抑制剂。PF74与HI
PT2385
(Catalog# : 1812135, Cas# :
1672665-49-4
)
PT2385是一种口服活性小分子缺氧诱导因子(HIF)-2alpha抑制剂,具有潜
PF 1022A
(Catalog# : 1811232, Cas# :
133413-70-4
)
PF1022A是一种新型的驱虫药,与嗜乳激素样跨膜受体结合,对线虫
普拉曲沙
(Catalog# : 1811221, Cas# :
146464-95-1
)
普拉曲沙是二氢叶酸还原酶(DHFR)的一种叶酸模拟抑制剂,对叶酸还
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag