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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
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Anilines
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Bromides
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Catalysts
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Deuterated
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技术服务
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 P
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产品名字索引 P
Pacritinib(SB1518)
(Catalog# : 122941, Cas# :
937272-79-2
)
Pacritinib (SB1518) 是一种高选择性激酶抑制剂,对 JAK2、FLT3、IRAK1 和
PHA-848125
(Catalog# : 122916, Cas# :
802539-81-7
)
PHA-848125 is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM; &g
PI-3065
(Catalog# : 122908, Cas# :
955977-50-1
)
PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhib
PD 123319
(Catalog# : 122903, Cas# :
130663-39-7
)
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of
PNU-282987
(Catalog# : 122827, Cas# :
123464-89-1
)
PNU-282987 is a selective 7 nicotinic acetylcholine receptor(7 nAChR) agonist with Ki
PF-431396
(Catalog# : 122818, Cas# :
717906-29-1
)
PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK
Posaconazole
(Catalog# : 122815, Cas# :
171228-49-2
)
Posaconazole is a broad-spectrum, second generation, triazole compound with antifunga
PQ401
(Catalog# : 122806, Cas# :
196868-63-0
)
PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylur
Pardoprunox
(Catalog# : 122523, Cas# :
269718-84-5
)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
PKC-IN-1
(Catalog# : 122520, Cas# :
1046787-18-1
)
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM; compound example H6 fro
PF-04447943
(Catalog# : 122515, Cas# :
1082744-20-4
)
PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and
PD-0325901
(Catalog# : 122405, Cas# :
391210-10-9
)
PD-0325901 i a potent bioavailable and selective MEK inhibitor, which targets mitogen
P005672 hydrochloride
(Catalog# : 122302, Cas# :
1035979-44-2
)
P005672 hydrochloride is used for antibacterial/anti-inflammatory acne treatment.
Pirodavir
(Catalog# : 122216, Cas# :
124436-59-5
)
Pirodavir is the prototype of a novel class of broad-spectrum antipicornavirus compou
PD173074
(Catalog# : 122212, Cas# :
219580-11-7
)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
Pyroxamide
(Catalog# : 121802, Cas# :
382180-17-8
)
Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic propertie
PKI-402
(Catalog# : 121421, Cas# :
1173204-81-3
)
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K/// and mTOR with IC50
PHA-665752
(Catalog# : 121418, Cas# :
477575-56-7
)
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9
Pimavanserin
(Catalog# : 120809, Cas# :
706779-91-1
)
Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x
Pemetrexed disodium
(Catalog# : 120704, Cas# :
150399-23-8
)
Coming soon!
PX-478
(Catalog# : 111307, Cas# :
685847-78-3
)
PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potentia
Pardoprunox hydrochloride
(Catalog# : 111010, Cas# :
269718-83-4
)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
PD153035 Hcl
(Catalog# : 111003, Cas# :
183322-45-4
)
PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM an
PRT-060318
(Catalog# : 110904, Cas# :
1194961-19-7
)
PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach
PCI-27483
(Catalog# : 110401, Cas# :
871266-63-6
)
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VI
PSEUDOLARIC ACID B
(Catalog# : 110223, Cas# :
82508-31-4
)
Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempfer
PL-100
(Catalog# : 102616, Cas# :
612547-11-2
)
PL-100 is a novel HIV-1 protease inhibitor (PI) with a favorable cross-resistance pro
propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate
(Catalog# : 102302, Cas# :
1334513-02-8
)
Coming soon!
PF-562271 benzenesulfonate salt
(Catalog# : 101919, Cas# :
939791-38-5
)
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion
2-Pyrimidineacetonitrile (9CI)
(Catalog# : 101903, Cas# :
59566-45-9
)
Coming soon!
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!