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Epigenetics
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MAPK
Cytoskeletal Signaling
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DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1189805-51-3 | (±)-Methotrimeprazine D6
(Catalog# : 61114)
()-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 d
1831110-54-3 | MS023
(Catalog# : 6111012)
MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC
100872-83-1 | ML346
(Catalog# : 611940)
ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
1207358-59-5 | mTOR-IN-1
(Catalog# : 611820)
mTOR-IN-1 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 1.5
1030612-87-3 | MK-8245
(Catalog# : 16070814)
MK-8245
1154025-82-6 | Molidustat (BAY85-3934)
(Catalog# : 16062901)
Molidustat (BAY85-3934)
1286770-55-5 | MK-8931 ( Verubecestat )
(Catalog# : 1662118)
Verubecestat(MK-8931) is a small-molecule inhibitor of beta-secretase cleaving enzyme
1796565-52-0 | MDK-5220
(Catalog# : 16060603)
MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excel
1350514-68-9 | MK-5172
(Catalog# : 032514)
Coming soon!
1202044-20-9 | MK-2866
(Catalog# : 030901)
Coming soon!
1032349-93-1 | MK-2206
(Catalog# : 011805)
MK-2206 2Hcl is an orally bioavailable allosteric inhibitor of the serine/threonine p
1001917-37-8 | MK-8033
(Catalog# : 011801)
MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt
1222800-79-4 | ML324
(Catalog# : 011301)
ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
1227923-29-6 | MK7622
(Catalog# : 51627)
MK-7622isused as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for t
1038915-60-4 | MK-4827
(Catalog# : 123007)
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with grea
118414-82-7 | MK 886
(Catalog# : 122217)
MK 886 is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenas
1430213-30-1 | ML216
(Catalog# : 122101)
ML216 is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing si
1010085-13-8 | MK-5108
(Catalog# : 121504)
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM; 220- and 190-
115550-35-1 | Marbofloxacin
(Catalog# : 121425)
Marbofloxacin is a potent antibiotic of which depends upon its inhibition of DNA-gyra
1162656-22-5 | MCB-613
(Catalog# : 111305)
Coming soon!
133407-82-6 | MG-132
(Catalog# : 111303)
MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain w
1303607-60-4 | MI-773
(Catalog# : 102207)
MI-773 is an orally available spiro-oxindole HDM2 (human double minute 2) antagonist
1265905-21-2 | methyl 2-((1R,3S)-3-amino-1-hydroxy-4-methylpentyl)thiazole-4-carboxylate
(Catalog# : 91809)
Coming soon!
1206524-85-7 | MK-5172 intermediate
(Catalog# : 91802)
MK-5172(Grazoprevir) intermediate
1206524-84-6 | Methyl (1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-
(Catalog# : 91801)
MK-5172(Grazoprevir) intermediate
183429-63-2 | METHYL 1-AMINO-1-CYCLOHEPTANECARBOXYLATE
(Catalog# : 83111)
Coming soon!
13623-25-1 | 6-Methoxy-1-indanone
(Catalog# : 81924)
Coming soon!
18372-22-0 | methyl 2-(1H-indol-3-yl)-2-oxoacetate
(Catalog# : 81921)
Coming soon!
196929-78-9 | 2-methylpropane-2-sulfinamide
(Catalog# : 81914)
Coming soon!
129799-08-2 | Methyl 4-Boc-Piperazine-2-Carboxylate
(Catalog# : 81704)
Coming soon!
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib is an oral interleukin-2-inducible T cell kinase (ITK) inhibitor.
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration
2765081-21-6 | RMC-6236
(Catalog# : 25074)
Daraxonrasib, also known as RMC-6236 and RAS-IN-2, is a potent and selective RAS(ON)
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel