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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
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Anilines
Boronic Acids
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Indoles and Oxindoles
Iodos
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Oxazoles
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Cas Index 1
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Cas Index 1
1262036-50-9 | LY2886721
(Catalog# : 121427)
LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
1418033-25-6 | LMK 235
(Catalog# : 120422)
LMK 235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor, which demons
1308256-94-1 | LHW090-A7
(Catalog# : 91810)
Coming soon!
1234480-84-2 | LRRK2-IN-1
(Catalog# : 81001)
LRRK2-IN-1 is a cell-permeable, ATP competitive, potent, and selective LRRK2 inhibito
1254473-64-7 | LY2874455
(Catalog# : 71801)
1) Sponsor: Eli Lilly and Company.2) Phase:Phase 12) LY2874455 is potent, selective,
1032900-25-6 | LDK378
(Catalog# : 52806)
LDK378(Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and
1062368-24-4 | LDN193189
(Catalog# : 52733)
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription
1627503-67-6 | LDN-214117
(Catalog# : 52707)
LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold
1432597-26-6 | LDN-212854
(Catalog# : 52588)
LDN-212854 is a potent and selectiveBMP receptorinhibitor with IC50 of 1.3 nM for ALK
1026680-07-8 | LB-100
(Catalog# : 52511)
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 M
154447-36-6 | LY294002
(Catalog# : 52309)
LY294002 is the first synthetic molecule known to inhibitPI3K//withIC50of 0.5 M/0.57
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
1208448-95-6 | MIF098
(Catalog# : 24150)
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.
1844849-10-0 | Mevrometostatum
(Catalog# : 24124)
Mevrometostatum is an enhancer of zeste homolog 2 (EZH2) inhibitor.
1398568-47-2 | Milademetan free base
(Catalog# : 20529)
Milademetan, also known as DS-3032b or DS-3032, is a potent and selective MDM2 inhibi
1424371-93-6 | MK-8189
(Catalog# : 20503)
MK-8189 is a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizo
1933460-19-5 | Mitiperstat
(Catalog# : 20457)
Mitiperstat is a myeloperoxidase inhibitor.
129047-38-7 | 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE
(Catalog# : 20398)
1032570-74-3 | 7-methoxy-8-[3-(4-morpholinyl)propoxy]-Imidazo[1,2-c]quinazolin-5-amine
(Catalog# : 20394)
1922153-17-0 | MELK-8a
(Catalog# : L20331)
MELK-8a Dihydrochloride is a novel inhibitor of maternal embryonic leucine zipper kin
1567915-38-1 | MTI-31
(Catalog# : L20329)
MTI-31 is a bioactive chemical.
1338934-59-0 | MKC-8866
(Catalog# : 20325)
MKC-8866, also known as IRE1-IN-8866, is an inhibitor of IRE1 RNase activity. MKC8866
1700637-55-3 | MDK-7553
(Catalog# : 20320)
MDK-7553, also known as CD38 inhibitor 78c and Compound-78c, is a potent CD38 inhibit
1354707-41-7 | Mitochonic Acid 5
(Catalog# : 204122)
Mitochonic Acid 5 is a derivative of the plant hormone indole-3-acetic acid. It has b
1394371-71-1 | MK-8722
(Catalog# : 20293)
MK-8722 is a potent pan-AMPK activator. MK-8722 improves glucose homeostasis but indu
1375066-73-1 | 3-Methyl-1,2,4-thiadiazole-5-carbohydrazide
(Catalog# : 21256)
1847461-43-1 | Mobocertinib free base
(Catalog# : 20111803)
Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with poten
1627138-52-6 | ML380
(Catalog# : 20103003)
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator
14920-87-7 | METHYL 2,6-DICHLOROBENZOATE
(Catalog# : 2071634)
115458-99-6 | Methyl (R)-2-(Benzyloxy)propionate
(Catalog# : 262325)
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib is an oral interleukin-2-inducible T cell kinase (ITK) inhibitor.
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration
2765081-21-6 | RMC-6236
(Catalog# : 25074)
Daraxonrasib, also known as RMC-6236 and RAS-IN-2, is a potent and selective RAS(ON)
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel