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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Bromides
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1193383-09-3 | JNJ-42041935
(Catalog# : 031401)
JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and
1639422-97-1 | JH-VIII-157-02
(Catalog# : 62103)
JH-VIII-157-02, a structural analogue of alectinib, is potent against the G1202R muta
1700693-08-8 | JH-II-127
(Catalog# : 012010)
JH-II-127 is a potent and selective inhibitor of both wild-type and G2019S mutant LRR
1127498-03-6 | JNJ 40411813
(Catalog# : 122939)
JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2
1210004-12-8 | JZL195
(Catalog# : 111007)
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and
1094873-14-9 | JNJ-31020028
(Catalog# : 100903)
JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropep
1146963-51-0 | J-147
(Catalog# : 52505)
J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) w
199596-05-9 | JIB-04
(Catalog# : 52225)
JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230, 34
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
1357164-52-3 | KUS121
(Catalog# : 20676)
KUS-121 is a small-molecule inhibitor of the transitional endoplasmic reticulum ATPas
1596348-16-1 | KDM5-C49
(Catalog# : 20493)
KDM5-C49 is a potent and selective inhibitor of KDM5 (also known as JARID1). KDM5-C49
1771756-32-1 | KUN56321
(Catalog# : 21246)
KUN56321 is a luminescent agent. The application of KUN56321 comprises: coating the f
1695533-89-1 | KO-947
(Catalog# : 20122101)
KO-947 is a potent and selective ERK inhibitor with slow dissociation kinetics. KO-94
1784282-12-7 | KHS101 HCl
(Catalog# : 191281)
KHS101 HCl is an inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It a
1646795-59-6 | KC01
(Catalog# : 1810294)
KC01 is a covalent inhibitor of ABHD16A. ABHD16A is a phosphatidylserine (PS) lipase
18228-17-6 | KG-501
(Catalog# : 1810226)
KG-501 is a cAMP response element-binding protein (CREB) inhibitor.
1131456-28-4 | KGP-94
(Catalog# : 3291806)
KGP94 is a reversible, time-dependent and competitive inhibitor of human cathepsin L.
1428729-56-9 | KIN-1148
(Catalog# : 184121)
KIN-1148 is a IRF3 agonist. KIN1148 induced dose-dependent IRF3 nuclear translocation
1799974-70-1 | KI-696
(Catalog# : 1710132)
KI-696 represents an excellent LMW tool to study the KEAP1-NRF2 interaction in vivo.
1261113-96-5 | KAF-156
(Catalog# : 20178211)
KAF-156. aslo known as GNF-156, is an antimalarials potentially for treatment of Mala
1188890-41-6 | KN-93 phosphate
(Catalog# : 16123029)
KN-93 is a CaMKII inhibitor. KN-93 suppresses ventricular arrhythmia induced by LQT2
191089-59-5 | K-7174
(Catalog# : 16123028)
K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myel
182004-65-5 | KB-R7943 mesylate
(Catalog# : 16122826)
KB-R7943 is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchang
142273-20-9 | Kenpaullone
(Catalog# : 16122711)
Kenpaullone is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs). It al
1309444-75-4 | K145
(Catalog# : 6111523)
K145 is a selective SphK2 inhibitor with an IC50 of 4.300.06 M , while no inhibition
1253452-78-6 | KS176
(Catalog# : 6111510)
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BC
1956356-56-1 | KYA1797K
(Catalog# : 6111416)
KYA1797K is a highly potent and selective Wnt/-catenin inhibitor with IC50 of 0.75 M
1354037-26-5 | KH-CB19
(Catalog# : 611922)
KH-CB19 is a potent and highly specific inhibitor of the CDC2-like kinase isoforms 1
1000669-72-6 | KW-2449
(Catalog# : 16071012)
KW-2449 is a novel multikinase inhibitor, which suppresses the growth of leukemia cel
1431985-92-0 | K02288
(Catalog# : 52728)
K02288 is a novel small molecule inhibitor of ALK1/2/3/6 with IC50s of 1.8/1.1/34.4/6
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1628606-05-2 | Vimseltinib free base
(Catalog# : 25047)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2128698-24-6 | 2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046)
1371587-51-7 | Cavosonstat
(Catalog# : 25045)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
259657-09-5 | Ivospemin Hydrochloride
(Catalog# : 25044)
Ivospemin is an antineoplastic spermine analogue.
2805997-46-8 | Survodutide
(Catalog# : 25043)
2595308-10-2 | XRD-0394
(Catalog# : 25042)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
1621999-82-3 | CC-90003
(Catalog# : 25041)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E