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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Boronic Acids
Bromides
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Deuterated
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Iodos
Nitro Compounds
Oxazoles
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Pyridines
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Cas Index 1
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Cas Index 1
1627710-50-2 | LJH685
(Catalog# : 16070903)
LJH685 is a potent pan-RSKinhibitor withIC50of 6 nM, 5 nM and 4 nM for RSK1, RSK2, an
1137608-69-5 | LX1606 (Hippurate)
(Catalog# : 16062301)
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibi
1165910-22-4 | LGD-4033(Ligandrol)
(Catalog# : 030907)
LGD-4033, also known as VK5211 and Ligandrol, is an investigational selective androge
191471-52-0 | LY-379268
(Catalog# : 011904)
Coming soon!
1350636-82-6 | Lefamulin acetate
(Catalog# : 011808)
Coming soon!
1061337-51-6 | Lefamulin
(Catalog# : 011807)
Coming soon!
111358-88-4 | Lestaurtinib
(Catalog# : 010815)
Lesraurtinib is an orally bioavailable indolocarbazole derivative with antineoplastic
1192189-69-7 | LX7101
(Catalog# : 010802)
LX7101 is a potent inhibitor of LIMK1/2, ROCK2 and PKA, with IC50 of 24/1.6, 10, and
1082949-67-4 | LY2584702 free base
(Catalog# : 122909)
LY2584702 is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and p
1082949-68-5 | LY2584702 tosylate
(Catalog# : 122907)
LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibi
1062368-62-0 | LDN193189 Hydrochloride
(Catalog# : 122830)
LDN193189 Hydrochloride is a selective BMP signaling inhibitor, inhibits the transcri
1005342-46-0 | LCL161
(Catalog# : 122820)
LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis
1234703-40-2 | LY2608204
(Catalog# : 122218)
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM.
1194044-20-6 | LY2811376
(Catalog# : 121435)
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
1262036-50-9 | LY2886721
(Catalog# : 121427)
LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
1418033-25-6 | LMK 235
(Catalog# : 120422)
LMK 235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor, which demons
1308256-94-1 | LHW090-A7
(Catalog# : 91810)
Coming soon!
1234480-84-2 | LRRK2-IN-1
(Catalog# : 81001)
LRRK2-IN-1 is a cell-permeable, ATP competitive, potent, and selective LRRK2 inhibito
1254473-64-7 | LY2874455
(Catalog# : 71801)
1) Sponsor: Eli Lilly and Company.2) Phase:Phase 12) LY2874455 is potent, selective,
1032900-25-6 | LDK378
(Catalog# : 52806)
LDK378(Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and
1062368-24-4 | LDN193189
(Catalog# : 52733)
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription
1627503-67-6 | LDN-214117
(Catalog# : 52707)
LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold
1432597-26-6 | LDN-212854
(Catalog# : 52588)
LDN-212854 is a potent and selectiveBMP receptorinhibitor with IC50 of 1.3 nM for ALK
1026680-07-8 | LB-100
(Catalog# : 52511)
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 M
154447-36-6 | LY294002
(Catalog# : 52309)
LY294002 is the first synthetic molecule known to inhibitPI3K//withIC50of 0.5 M/0.57
1398568-47-2 | Milademetan free base
(Catalog# : 20529)
Milademetan, also known as DS-3032b or DS-3032, is a potent and selective MDM2 inhibi
1424371-93-6 | MK-8189
(Catalog# : 20503)
MK-8189 is a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizo
1933460-19-5 | Mitiperstat
(Catalog# : 20457)
Mitiperstat is a myeloperoxidase inhibitor.
129047-38-7 | 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE
(Catalog# : 20398)
1032570-74-3 | 7-methoxy-8-[3-(4-morpholinyl)propoxy]-Imidazo[1,2-c]quinazolin-5-amine
(Catalog# : 20394)
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag