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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1404437-62-2 | ML-281
(Catalog# : 17022811)
ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nan
1502816-23-0 | MS049
(Catalog# : 17021313)
MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM
1313883-00-9 | Miransertib(ARQ 092)
(Catalog# : 17021301)
ARQ 092 is a novel, orally bioavailable and selective AKT pathway inhibitor exhibit
1399840-35-7 | MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
110448-33-4 | ML-7
(Catalog# : 17011107)
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki
1005264-47-0 | MX69
(Catalog# : 17011105)
MX69 is a MDM2/XIAP inhibitor, used for cancer treatment.
115104-28-4 | MK-571 sodium salt
(Catalog# : 16123055)
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the bindin
1445993-26-9 | Mivebresib
(Catalog# : 16123052)
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-cont
1198097-97-0 | Mirin
(Catalog# : 16123049)
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor.
1047953-91-2 | MI-2 (MALT1 inhibitor)
(Catalog# : 16123047)
MI-2 is a MALT1 inhibitor (IC50 = 5.84 M). MI-2 binds directly to MALT1 and irreversi
110044-82-1 | MG-101
(Catalog# : 16123046)
MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.
139504-50-0 | Mertansine (DM1)
(Catalog# : 16123045)
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2-deacetyl-N2-(3-mercap
129831-99-8 | MC-976
(Catalog# : 16122832)
MC-976 is an Vitamin D3 derivative.
115103-85-0 | MK571
(Catalog# : 161227105)
MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor)
1572414-83-5 | ML323
(Catalog# : 16122790)
ML323 is a highly potent and selective USP1-UAF1 inhibitor with IC50 of 76 nM.ML323 i
1190378-57-4 | MRT67307
(Catalog# : 16122745)
MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, re
1038915-73-9 | MK-4827(Niraparib) tosylate
(Catalog# : 16122717)
MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8
1227962-62-0 | Marinopyrrole A
(Catalog# : 6111403)
Marinopyrrole (Maritoclax) is a novel and specific Mcl-1 inhibitor with an IC50 value
1338824-21-7 | ML224
(Catalog# : 61116)
ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimula
1189805-51-3 | (±)-Methotrimeprazine D6
(Catalog# : 61114)
()-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 d
1831110-54-3 | MS023
(Catalog# : 6111012)
MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC
100872-83-1 | ML346
(Catalog# : 611940)
ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
1207358-59-5 | mTOR-IN-1
(Catalog# : 611820)
mTOR-IN-1 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 1.5
1030612-87-3 | MK-8245
(Catalog# : 16070814)
MK-8245
1154025-82-6 | Molidustat (BAY85-3934)
(Catalog# : 16062901)
Molidustat (BAY85-3934)
1286770-55-5 | MK-8931 ( Verubecestat )
(Catalog# : 1662118)
Verubecestat(MK-8931) is a small-molecule inhibitor of beta-secretase cleaving enzyme
1796565-52-0 | MDK-5220
(Catalog# : 16060603)
MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excel
1350514-68-9 | MK-5172
(Catalog# : 032514)
Coming soon!
1202044-20-9 | MK-2866
(Catalog# : 030901)
Coming soon!
1032349-93-1 | MK-2206
(Catalog# : 011805)
MK-2206 2Hcl is an orally bioavailable allosteric inhibitor of the serine/threonine p
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.
98570-83-3 | Phylloflavan
(Catalog# : 24155)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW