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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Anilines
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Cas Index 1
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Cas Index 1
1253584-84-7 | NMS-E973
(Catalog# : 1810293)
NMS-E973 is a novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
153587-01-0 | NS1619
(Catalog# : 1810227)
NS1619 is a Bkca opener or large-conductance Ca2+-activated potassium (BKCa, KCa1.1)
1452458-86-4 | Nacubactam
(Catalog# : 185169)
Nacubactam, also known as RG-6080, FPI-1459, and OP-0595, is a beta-lactamase inhibit
108852-90-0 | Nemorubicin
(Catalog# : 185167)
Nemorubicin, also known as PNU152243A, is a doxorubicin derivative that differs signi
152946-68-4 | Nolatrexed HCl
(Catalog# : 185166)
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential a
1773489-72-7 | Nidufexor
(Catalog# : 184288)
Nidufexor is a farnesoid X receptor (FXR) agonist.
1422144-42-0 | Netarsudil(Mesylate)
(Catalog# : 712181)
Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Net
1140844-63-8 | nor-NOHA acetate
(Catalog# : 1710169)
nor-NOHA is a potent, selective, competitive, and high affinity inhibitor of arginase.
1262417-51-5 | NMS-P118
(Catalog# : 17101311)
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor with ex
1508250-71-2 | Nazartinib (EGF816)
(Catalog# : 1781004)
Nazartinib, also known as EGF816, is an orally available, irreversible, third-generat
1254032-66-0 | Netarsudil
(Catalog# : 1781001)
<span style="color:#34495E;font-family:" font-size:14px;background-color
1676893-24-5 | NSC781406
(Catalog# : 20178810)
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3K.
1916571-90-8 | NCT-503
(Catalog# : 2017888)
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serin
1304630-27-0 | NGP-555
(Catalog# : 2017875)
NGP 555 is being developed as a preventative disease modifying therapy for Alzheimer'
147149-76-6 | Nolatrexed
(Catalog# : 17030908)
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential a
1221713-92-3 | NPS-1034
(Catalog# : 17030907)
NPS-1034 is a novel MET inhibitor, which inhibits the activated MET receptor and its
1400-61-9 | Nystatin
(Catalog# : 17030905)
Nystatin is a polyene antifungal, the antibiotic complex containing three biologicall
1354744-91-4 | Naloxegol Oxalate
(Catalog# : 17030202)
Naloxegol, also known as NKTR-118 and AZ-13337019, is a peripherally-selective opioid
1038915-64-8 | Niraparib HCl
(Catalog# : 17030114)
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PAR
1698878-14-6 | Nampt-IN-1
(Catalog# : 17022705)
Nampt-IN-1 is a novel inhibitor of NAMPT with IC50 of 18 nM (NCI-H1155 cell), 49 nM (
102586-30-1 | NSC12
(Catalog# : 17021317)
NSC12 is an orally available pan-FGF trap able to inhibit FGF2/FGFR interaction and
123653-11-2 | NS-398 (NS398)
(Catalog# : 17011106)
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for hum
1253952-02-1 | Netarsudil (AR-13324) 2HCl
(Catalog# : 1710901)
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is cu
1313363-54-0 | NVP-CGM097
(Catalog# : 16122789)
NVP-CGM097 is a highly potent and selective MDM2 inhibitor. It binds to the p53 bindi
113104-25-9 | NSC228155
(Catalog# : 16122779)
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and mo
175026-96-7 | NQDI-1
(Catalog# : 16122772)
NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute
1360614-48-7 | Necrosulfonamide
(Catalog# : 6111508)
Necrosulfonamide is a very specific and potent necrosis inhibitor and blocks mixed li
154447-35-5 | NU 7026
(Catalog# : 6118017)
NU 7026 is a novel and potential inhibitor of the DNA repair enzyme DNA-dependent pro
1449236-96-7 | NMS-859
(Catalog# : 161014001)
NMS-859 is a potent and specific small molecule covalent inhibitor of the ATPase VCP/
1802088-50-1 | NCT-501
(Catalog# : 16071414)
NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize rea
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1628606-05-2 | Vimseltinib free base
(Catalog# : 25047)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2128698-24-6 | 2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046)
1371587-51-7 | Cavosonstat
(Catalog# : 25045)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
259657-09-5 | Ivospemin Hydrochloride
(Catalog# : 25044)
Ivospemin is an antineoplastic spermine analogue.
2805997-46-8 | Survodutide
(Catalog# : 25043)
2595308-10-2 | XRD-0394
(Catalog# : 25042)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
1621999-82-3 | CC-90003
(Catalog# : 25041)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E