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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Indoles and Oxindoles
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Deuterated
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Nitro Compounds
Oxazoles
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Pyridines
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Cas Index 1
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Cas Index 1
1242156-23-5 | RN486
(Catalog# : 52706)
RN486 is a selective Btk inhibitor with an IC50 Value of 4.0 nM.
196597-26-9 | Ramelteon
(Catalog# : 52602)
Ramelteon (TAK-375; Rozerem)is a melatonin receptor agonist with both high affinity f
1062243-51-9 | Ro3280
(Catalog# : 52826)
RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50
186692-46-6 | Roscovitine
(Catalog# : 52570)
Roscovitine (Seliciclib, CYC202) is a potent and selective CDK inhibitor for Cdc2, CD
199666-03-0 | Ro 61-8048
(Catalog# : 51501)
Ro 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 o
156722-18-8 | Rostafuroxin
(Catalog# : 52204)
Rostafuroxin(PST 2238) is a antihypertensive compound; Na,K-ATPase antognist;displace
1316214-52-4 | Rocilinostat (ACY-1215)
(Catalog# : 52104)
Rocilinostat (ACY-1215) is a selectiveHDAC6inhibitor withIC50of 5 nM. It is >10-fo
1225497-78-8 | Rigosertib sodium
(Catalog# : 52010)
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor ofPLK1withIC50of 9 nM. It sh
1211441-98-3 | Ribociclib (LEE011)
(Catalog# : 51911)
Ribociclib (LEE011) is an orally available, and highly specificCDK4/6inhibitor. Phase
152121-30-7 | SB-202190
(Catalog# : 24106)
SB-202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinas
1648843-04-2 | SX-682
(Catalog# : 24082)
SX-682 is a potent and selective Cxcr1/2 inhibitor potentially useful for castration-
1933514-13-6 | Sebetralstat free base
(Catalog# : 24048)
Sebetralstat, also known as KVD-900, is a fast-acting oral PKa inhibitor that rapidly
1878218-66-6 | SY-008 Acetate
(Catalog# : 24016)
SY-008 is a sodium glucose transporter 1 (SGLT1) inhibitor.
1480443-32-0 | SY-008
(Catalog# : 24021)
SY-008 is a sodium glucose transporter 1 (SGLT1) inhibitor.
194032-32-1 | (S)-1-BOC-2-METHYL-[1,4]DIAZEPANE
(Catalog# : 20541)
131690-60-3 | (S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
(Catalog# : 20516)
1980023-96-8 | (S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine
(Catalog# : 20396)
100874-08-6 | SB-4 agonist
(Catalog# : G20378)
SB 4 is a potent BMP4 agonist.
1310422-41-3 (HCl) | SEP-363856 HCl ( SEP-856 )
(Catalog# : 822222)
SEP-363856 is a novel trace amine receptor 1 (TAAR1) agonist with serotonin 5-HT1A ac
1629138-41-5 | SRI-011381
(Catalog# : L20355)
SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer
1449597-34-5 | SMN-C3
(Catalog# : 20344)
SMN-C3is an orally active SMN2 splicing modulator and has the potential to treat spin
1619931-27-9 | Seralutinib
(Catalog# : 21238)
Seralutinib, also known as PK-10571 and GB002, is a Novel Inhaled Pdgfr Kinase Inhibi
1446712-19-1 | SNG-1153
(Catalog# : 21228)
SNG-1153 is a modulator of estrogen receptor ER-alpha36.
1293281-49-8 | Seltorexant
(Catalog# : 81498)
Seltorexant, also known as JNJ-42847922 and MIN-202, is a selective orexin-2 receptor
1401682-78-7 | Senaparib
(Catalog# : 20103002)
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with
1433953-83-3 | SAR 131675
(Catalog# : 2091901)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
18298-32-4 | SB 225002
(Catalog# : 2071510)
1369767-20-3 | ((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
(Catalog# : 202331)
The bulk may be provided by custom synthesis.
1393477-72-9 (free base) | Selinexor free base
(Catalog# : 2051501)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
1330782-76-7 | Simurosertib
(Catalog# : 2041504)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag