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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
Anilines
Boronic Acids
Bromides
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Iodos
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Cas Index 1
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Cas Index 1
122323-88-0 | Piperazine-2-Carboxylic Acid Methyl Ester Dihydrochloride
(Catalog# : 81817)
Coming soon!
137071-32-0 | Pimecrolimus
(Catalog# : 81302)
Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic rec
147526-32-7 | Pitavastatin Calcium
(Catalog# : 81301)
Pitavastatin is a member of the blood cholesterol lowering medication class of statin
1197160-78-3 | PKI-587
(Catalog# : 73109)
PKI-587 is a potent inhibitor to PI3K-, PI3K-, and mTOR (FRAP) with IC50 of 0.4 nM, 5
1263-89-4 | Paromomycin Sulfate
(Catalog# : 52815)
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in
1029044-16-3 | Pexidartinib
(Catalog# : 52753)
pexidartinib is acapsule formulation containing a small-molecule receptor tyrosine ki
1415562-82-1 | PF-543
(Catalog# : 52740)
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sph
1190307-88-0 | PSI-7977
(Catalog# : 52718)
PSI-7977(sofosbuvir) is an investigational nucleotide analog for treatment of chronic
1092364-38-9 | Poziotinib
(Catalog# : 52634)
Poziotinib(NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3
1255517-76-0 | PF-4708671
(Catalog# : 52631)
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), w
157716-52-4 | Perifosine
(Catalog# : 52613)
Perifosine (KRX-0401; D-21266; NSC 639966) is a novel Akt inhibitor with IC50 of 4.7
1191951-57-1 | PHT-427
(Catalog# : 52583)
PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains o
1349796-36-6 | PI3K-IN-1
(Catalog# : 52560)
PI3K-IN-1 is a potent inhibitor of PI3K, more information can be found in patent WO20
152121-53-4 | PD 169316
(Catalog# : 52513)
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 =
153436-54-5 | PD153035
(Catalog# : 52223)
PD153035(ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and I
1627676-59-8 | PFI-2
(Catalog# : 52113)
PFI-2 is a potent, selective, and cell-activelysine methyltransferase SETD7inhibitor
1454846-35-5 | PF-06463922
(Catalog# : 51701)
PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosin
150323-78-7 | Quipazine dimaleate
(Catalog# : 20462)
Quipazine dimaleate is a selective 5-HT3 receptor agonist that also displays antagoni
1893397-65-3 | QUN97653
(Catalog# : 204507)
QUN97653, also known as TBK1/IKKε-IN-5, is a dual TBK1 and IKKε inhibitor, with IC5
1334719-95-7 | Q-203
(Catalog# : 17106003)
Q-203 is a potent, selective new drug.
1135695-98-5 | Q-VD-OPH
(Catalog# : 16071010)
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inh
144875-48-9 | Qesiquimod
(Catalog# : 120814)
Qesiquimod is a potent synthetic agonist of TLR7/TLR8 that possesses antiviral and an
1443361-20-3 | 3-Quinolinecarboxylic acid, 1,4-dihydro-8- methoxy-1-[(4-methoxyphenyl)methyl]-4-oxo-, ethyl ester
(Catalog# : 102902)
Coming soon!
1237744-13-6 | QNZ46
(Catalog# : 91006)
QNZ46 is a noncompetitive and voltage-independent antagonist selective for NR2C/D con
1496510-51-0 | Relacorilant
(Catalog# : 25035)
Relacorilant is discontinued.
1494684-33-1 | Risovalisib mesylate
(Catalog# : 24078)
CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598
1423719-27-0 | (R,S)-BI 1015550
(Catalog# : 230403)
BI 1015550 is a novel PDE4 inhibitor showing a preferential enzymatic inhibition of P
139339-45-0 | Ro 24-7429
(Catalog# : 2320201)
Ro24-7429 is a potent and orally activeHIV-1transactivator proteinTatantagonist. Ro24
1239729-06-6 | RP-5063(Brilaroxazine)
(Catalog# : 822224)
RP-5063(Brilaroxazine) is a multimodal modulator of serotonin and dopamine recept
1859053-21-6 | Rucaparib Camsylate
(Catalog# : 20316)
Rucaparib camsylate is a potent, orally available inhibitor of poly ADP-ribose polyme
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1628606-05-2 | Vimseltinib free base
(Catalog# : 25047)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2128698-24-6 | 2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046)
1371587-51-7 | Cavosonstat
(Catalog# : 25045)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
259657-09-5 | Ivospemin Hydrochloride
(Catalog# : 25044)
Ivospemin is an antineoplastic spermine analogue.
2805997-46-8 | Survodutide
(Catalog# : 25043)
2595308-10-2 | XRD-0394
(Catalog# : 25042)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
1621999-82-3 | CC-90003
(Catalog# : 25041)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E