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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Amino Acids
Anilines
Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
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Cas Index 1
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Cas Index 1
1144035-53-9 | PF-8380
(Catalog# : 17030115)
PF-8380 is a potent autotaxin inhibitor with an IC(50) of 2.8 nM in isolated enzyme a
153168-05-9 | Pleconaril
(Catalog# : 17030111)
Pleconaril is an antiviral drug potentially for the treatment of enterovirus infectio
1235481-90-9 | P7C3-A20
(Catalog# : 16122838)
P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-
13309-08-5 | 3PO
(Catalog# : 161227109)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
1393465-84-3 | PLX7904
(Catalog# : 16122777)
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
1452-77-3 | Picolinamide
(Catalog# : 16122714)
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuc
185039-89-8 | PD0166285
(Catalog# : 16122710)
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentratio
1415562-83-2 | PF-543 Citrate
(Catalog# : 6111525)
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-
1819363-80-8 | PFI-3
(Catalog# : 6111020)
PFI-3
1173111-67-5 | PF-04929113 Mesylate
(Catalog# : 611939)
PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median
1429624-84-9 | PI4KIIIbeta-IN-9
(Catalog# : 611908)
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
1881233-39-1 | PI4KIIIbeta-IN-10
(Catalog# : 611907)
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very
1235449-52-1 | PI3Kα inhibitor 1
(Catalog# : 611903)
PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, comp
1220699-06-8 | PF-04979064
(Catalog# : 611902)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
1927857-56-4 | PQR620
(Catalog# : 611821)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
1092788-83-4 | PP121
(Catalog# : 161009011)
PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyros
1276553-09-3 | PF-4989216
(Catalog# : 161009002)
PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently
1180676-32-7 | PS 48
(Catalog# : 16071111)
PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1,
1356033-60-7 | Panulisib
(Catalog# : 16071030)
Panulisib, also known as AK151761, is a potent and selective imidazoquinoline based P
152918-18-8 | Piclidenoson
(Catalog# : 16071028)
Piclidenoson, also known as CF101, is a specific agonist to the A3 adenosine receptor
1180676-33-8 | PS47
(Catalog# : 16070703)
PS47
1477-24-3 | 5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione
(Catalog# : 16062108)
5-PYRIDIN-4-YL-4H-[1,2,4]TRIAZOLE-3-THIOL
1216941-48-8 | Paritaprevir
(Catalog# : 16060702)
Paritaprevir, also known as ABT-450, is an acylsulfonamide inhibitor of the NS3-4A se
1388712-98-8 | 2-Pyridinemethanamine, N-[2-(diphenylphosphino)ethyl]-
(Catalog# : 032407)
Coming soon!
1469284-78-3 | PF-06424439
(Catalog# : 020202)
PF-06424439 is a potent and selective Diacylglycerol Acyltransferase 2 ( DGAT2) inhib
1808094-07-6 | PF-06471553
(Catalog# : 020201)
PF-06471553 is a potent and selective Monoacylglycerol acyltransferase 3 (MGAT3) inhi
1435467-37-0 | PF-06282999
(Catalog# : 020102)
PF-06282999 is an irreversible inactivator of myeloperoxidase, and currently in clini
1111636-35-1 | PF-04880594
(Catalog# : 012008)
PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerizatio
1061353-68-1 | PND-1186
(Catalog# : 010821)
PND-1186 is a potent FAK inhibitor with a 50% inhibitory concentration of 1.5 nM in v
1373615-35-0 | PF-5274857
(Catalog# : 010423)
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.
98570-83-3 | Phylloflavan
(Catalog# : 24155)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW