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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
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Bromides
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Indoles and Oxindoles
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
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Cas Index 1
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Cas Index 1
1234015-55-4 | Prexasertib mesylate
(Catalog# : 17986)
Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor.
192705-79-6 | PD166866
(Catalog# : 178814)
PD166866 has clear antiproliferative effects.
135729-61-2 | Palonosetron
(Catalog# : 2017080119)
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemothera
1776112-90-3 | PF-06747775
(Catalog# : 175161)
PF-06747775(PF06747775;CAS 1776112-90-3) is an orally available inhibitor of the epid
1331782-27-4 | PF-04995274
(Catalog# : 17031017)
PF-04995274 is a 5-HT4 receptor partial agonist. It thought to act centrally as a pro
113906-27-7 | PNU-74654
(Catalog# : 17031011)
PNU-75654 disrupts the Wnt signaling pathway via inhibition of the interaction (KD5
127317-03-7 | PACAP 1-27
(Catalog# : 17031005)
Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is a potent PACAP re
1462249-75-7 | PFK-158
(Catalog# : 17030915)
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fruct
1235403-62-9 | PF-05089771
(Catalog# : 17030912)
PF-05089771 is a Selective Nav1.7 Inhibitor (IC50 = 11 nM) that interacts with the vo
135-87-5 | Piperoxan HCl
(Catalog# : 17030708)
Piperoxan, also known as benodaine, is a drug which was the very first antihistamine
1403764-72-6 | PFI-1
(Catalog# : 17030704)
PFI-1 is a potent and highly selective protein interaction Inhibitor, which targets B
1114544-31-8 | Ponatinib HCl
(Catalog# : 17030607)
Ponatinib, also known as AP24534 is an oral drug for the treatment of chronic myeloid
192705-80-9 | PD-161570
(Catalog# : 17030304)
PD-161570 is a selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR
1402438-74-7 | PF-06273340
(Catalog# : 17030201)
PF-06273340 is a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor wit
1144035-53-9 | PF-8380
(Catalog# : 17030115)
PF-8380 is a potent autotaxin inhibitor with an IC(50) of 2.8 nM in isolated enzyme a
153168-05-9 | Pleconaril
(Catalog# : 17030111)
Pleconaril is an antiviral drug potentially for the treatment of enterovirus infectio
1235481-90-9 | P7C3-A20
(Catalog# : 16122838)
P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-
13309-08-5 | 3PO
(Catalog# : 161227109)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
1393465-84-3 | PLX7904
(Catalog# : 16122777)
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
1452-77-3 | Picolinamide
(Catalog# : 16122714)
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuc
185039-89-8 | PD0166285
(Catalog# : 16122710)
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentratio
1415562-83-2 | PF-543 Citrate
(Catalog# : 6111525)
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-
1819363-80-8 | PFI-3
(Catalog# : 6111020)
PFI-3
1173111-67-5 | PF-04929113 Mesylate
(Catalog# : 611939)
PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median
1429624-84-9 | PI4KIIIbeta-IN-9
(Catalog# : 611908)
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
1881233-39-1 | PI4KIIIbeta-IN-10
(Catalog# : 611907)
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very
1235449-52-1 | PI3Kα inhibitor 1
(Catalog# : 611903)
PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, comp
1220699-06-8 | PF-04979064
(Catalog# : 611902)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
1927857-56-4 | PQR620
(Catalog# : 611821)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
1092788-83-4 | PP121
(Catalog# : 161009011)
PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyros
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib is an oral interleukin-2-inducible T cell kinase (ITK) inhibitor.
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration
2765081-21-6 | RMC-6236
(Catalog# : 25074)
Daraxonrasib, also known as RMC-6236 and RAS-IN-2, is a potent and selective RAS(ON)
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel