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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1917294-46-2 | PF-04745637
(Catalog# : 2071623)
PF-04745637 is a TRPV1 antagonist.
1629869-44-8 | Pimodivir ( VX-787 )
(Catalog# : 2071401)
Pimodivir, also known as VX-787, JNJ-872, is a novel inhibitor of influenza virus rep
1454619-14-7 | PU-WS13
(Catalog# : 206701)
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-
1953130-87-4 | PTI-428(PTI428)
(Catalog# : 31619)
PTI-428 is a type of CFTR modulator called an amplifier. Amplifiers increase the amou
1415637-72-7 | PF-05085727
(Catalog# : 1932011)
PF-05085727 is a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibito
1252637-35-6 | Petesicatib
(Catalog# : 193206)
Petesicatib is a cathepsin inhibitor drug candidate.
187235-37-6 | Pretomanid
(Catalog# : 193110)
Pretomanid, aslo known as PA-824, a bioreductive drug. PA-824 has potent in vitro act
1341224-83-6 | PF-4136309
(Catalog# : 192282)
PF-4136309, also known as INCB8761, is an orally available human chemokine receptor 2
1078166-57-0 | PF04418948
(Catalog# : 191141)
PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist.
1352879-65-2 | PF74
(Catalog# : 1812253)
PF-3450074, also known as PF74, is a HIV-1 inhibitor that targets HIV capsid protein.
1672665-49-4 | PT2385
(Catalog# : 1812135)
PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF
133413-70-4 | PF 1022A
(Catalog# : 1811232)
PF1022A is a novel anthelmintic that binds to the latrophilin-like transmembrane rece
146464-95-1 | Pralatrexate
(Catalog# : 1811221)
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibit
1037589-69-7 | PF-05231023
(Catalog# : 1811162)
PF-05231023 is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and imp
1311174-68-1 | PH-002
(Catalog# : 1810234)
PH-002 is a novel inhibitor of apolipoprotein (apo) E4 intramolecular domain interact
1513857-77-6 | Pemigatinib (INCB054828)
(Catalog# : 1810164)
Pemigatinib (INCB054828) is an orally active, selectiveFGFRinhibitor withIC50s of 0.4
1022899-36-0 | PCI-33380
(Catalog# : 18943)
PCI-33380 was designed based on the ibrutinib scaffold and has been used in both cell
1613373-33-3 | PCO371
(Catalog# : 187125)
PCO371 is a potent and selective PTHR1 agonist for the treatment of hypoparathyroidis
1927857-61-1 | PQR530
(Catalog# : 18756)
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor.
1269662-73-8 | Pyrotinib
(Catalog# : 18731)
Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor
1268244-85-4 | PX20606 trans-isomer
(Catalog# : 186274)
PX20606, also known as PX-102, is a FXR agonist.
1394033-54-5 | PF-05180999
(Catalog# : 186153)
PF-05180999 is a potent and selective PDE2a inhibitor (PDE2a IC50 = 0.001 μM, 2000-f
1428333-96-3 | Pritelivir mesylate
(Catalog# : 186152)
Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhib
1446261-44-4 | Pamiparib
(Catalog# : 185233)
Pamiparib is an antineoplastic drug candidate.Pamiparib (BGB-290) is an investigation
1005168-10-4 | PAC 14028
(Catalog# : 185223)
PAC 14028, also known as Asivatrep, is a vanilloid VR1 receptor (TRPV1) antagonist po
1402727-29-0 | PE859
(Catalog# : 185157)
PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66
190383-31-4 | PD 168 077
(Catalog# : 185156)
PD168077 is a dopamine D4 receptor agonist which has a facilitatory effect on memory
1622291-66-0 | PF-06462894
(Catalog# : 185155)
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM).
1393124-08-7 | PF-06291874
(Catalog# : 185154)
PF-06291874 is a glucagon receptor antagonist and potentially usefully for patients w
1353552-97-2 | Poseltinib
(Catalog# : 185153)
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1628606-05-2 | Vimseltinib free base
(Catalog# : 25047)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2128698-24-6 | 2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046)
1371587-51-7 | Cavosonstat
(Catalog# : 25045)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
259657-09-5 | Ivospemin Hydrochloride
(Catalog# : 25044)
Ivospemin is an antineoplastic spermine analogue.
2805997-46-8 | Survodutide
(Catalog# : 25043)
2595308-10-2 | XRD-0394
(Catalog# : 25042)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
1621999-82-3 | CC-90003
(Catalog# : 25041)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E