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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1927857-61-1 | PQR530
(Catalog# : 18756)
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor.
1269662-73-8 | Pyrotinib
(Catalog# : 18731)
Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor
1268244-85-4 | PX20606 trans-isomer
(Catalog# : 186274)
PX20606, also known as PX-102, is a FXR agonist.
1394033-54-5 | PF-05180999
(Catalog# : 186153)
PF-05180999 is a potent and selective PDE2a inhibitor (PDE2a IC50 = 0.001 μM, 2000-f
1428333-96-3 | Pritelivir mesylate
(Catalog# : 186152)
Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhib
1446261-44-4 | Pamiparib
(Catalog# : 185233)
Pamiparib is an antineoplastic drug candidate.Pamiparib (BGB-290) is an investigation
1005168-10-4 | PAC 14028
(Catalog# : 185223)
PAC 14028, also known as Asivatrep, is a vanilloid VR1 receptor (TRPV1) antagonist po
1402727-29-0 | PE859
(Catalog# : 185157)
PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66
190383-31-4 | PD 168 077
(Catalog# : 185156)
PD168077 is a dopamine D4 receptor agonist which has a facilitatory effect on memory
1622291-66-0 | PF-06462894
(Catalog# : 185155)
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM).
1393124-08-7 | PF-06291874
(Catalog# : 185154)
PF-06291874 is a glucagon receptor antagonist and potentially usefully for patients w
1353552-97-2 | Poseltinib
(Catalog# : 185153)
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
1353900-92-1 | Pibrentasvir
(Catalog# : 185148)
Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the trea
172889-27-9 | PP2
(Catalog# : 185146)
PP2, also known as AG 1879, is a substance that has frequently been used in cancer re
172889-26-8 | PP1
(Catalog# : 185145)
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor.
146949-21-5 | Pocapavir
(Catalog# : 185144)
Pocapavir, also known as SCH-48973 and V-073, is a potent, selective, antienterovirus
1702967-37-0 | PSMA617 TFA
(Catalog# : 185143)
PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to
1472611-44-1 | Pyridostatin TFA salt
(Catalog# : 185142)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
1811510-56-1 | PF-06260933
(Catalog# : 18544)
PF-06260933 is a potent and highly selective inhibitor of MAP4K4.
1627929-55-8 | PLX51107
(Catalog# : 184285)
PLX51107 is a potent and selective BRD4 inhibitor or BET inhibitor with novel in vitr
171179-06-9 | PD 158780
(Catalog# : 184284)
PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epide
1997387-43-5 | PZM21
(Catalog# : 184162)
PZM21 is a potent Gi activator with exceptional selectivity for μOR and minimal β-a
1627607-87-7 | PFI-2 hydrochloride
(Catalog# : 184106)
PFI-2 is a potent inhibitor of SETD7 with IC50 2 nM and 1000-fold selectivity over ot
198474-05-4 | PF-0684000
(Catalog# : 184318)
PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-06
1467057-23-3 | PF-06409577
(Catalog# : 18434)
PF-06409577 is a potent and selective activator of 5′ adenosine monophosphate-activ
1802929-43-6 | PRN-1371
(Catalog# : 17101614)
PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. P
1293395-67-1 | PF-5006739
(Catalog# : 17101612)
PF-5006739 is a Potent CK1δ/ε inhibitor. PF-5006739 attenuates opioid drug-seeking
1383719-97-8 | PF-04628935
(Catalog# : 17101611)
PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth ho
1210608-43-7 | PIM447
(Catalog# : 1710134)
PIM447, also known as LGH447, is a potent Moloney murine leukemia (PIM) 1, 2, and 3 k
179474-81-8 | Pyridostatin TFA salt
(Catalog# : 1791517)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag