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PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Cas Index 1
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Cas Index 1
1005168-10-4 | PAC 14028
(Catalog# : 185223)
PAC 14028, also known as Asivatrep, is a vanilloid VR1 receptor (TRPV1) antagonist po
1402727-29-0 | PE859
(Catalog# : 185157)
PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66
190383-31-4 | PD 168 077
(Catalog# : 185156)
PD168077 is a dopamine D4 receptor agonist which has a facilitatory effect on memory
1622291-66-0 | PF-06462894
(Catalog# : 185155)
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM).
1393124-08-7 | PF-06291874
(Catalog# : 185154)
PF-06291874 is a glucagon receptor antagonist and potentially usefully for patients w
1353552-97-2 | Poseltinib
(Catalog# : 185153)
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
1353900-92-1 | Pibrentasvir
(Catalog# : 185148)
Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the trea
172889-27-9 | PP2
(Catalog# : 185146)
PP2, also known as AG 1879, is a substance that has frequently been used in cancer re
172889-26-8 | PP1
(Catalog# : 185145)
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor.
146949-21-5 | Pocapavir
(Catalog# : 185144)
Pocapavir, also known as SCH-48973 and V-073, is a potent, selective, antienterovirus
1702967-37-0 | PSMA617 TFA
(Catalog# : 185143)
PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to
1472611-44-1 | Pyridostatin TFA salt
(Catalog# : 185142)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
1811510-56-1 | PF-06260933
(Catalog# : 18544)
PF-06260933 is a potent and highly selective inhibitor of MAP4K4.
1627929-55-8 | PLX51107
(Catalog# : 184285)
PLX51107 is a potent and selective BRD4 inhibitor or BET inhibitor with novel in vitr
171179-06-9 | PD 158780
(Catalog# : 184284)
PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epide
1997387-43-5 | PZM21
(Catalog# : 184162)
PZM21 is a potent Gi activator with exceptional selectivity for μOR and minimal β-a
1627607-87-7 | PFI-2 hydrochloride
(Catalog# : 184106)
PFI-2 is a potent inhibitor of SETD7 with IC50 2 nM and 1000-fold selectivity over ot
198474-05-4 | PF-0684000
(Catalog# : 184318)
PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-06
1467057-23-3 | PF-06409577
(Catalog# : 18434)
PF-06409577 is a potent and selective activator of 5′ adenosine monophosphate-activ
1802929-43-6 | PRN-1371
(Catalog# : 17101614)
PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. P
1293395-67-1 | PF-5006739
(Catalog# : 17101612)
PF-5006739 is a Potent CK1δ/ε inhibitor. PF-5006739 attenuates opioid drug-seeking
1383719-97-8 | PF-04628935
(Catalog# : 17101611)
PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth ho
1210608-43-7 | PIM447
(Catalog# : 1710134)
PIM447, also known as LGH447, is a potent Moloney murine leukemia (PIM) 1, 2, and 3 k
179474-81-8 | Pyridostatin TFA salt
(Catalog# : 1791517)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
179474-85-2 | Prucalopride Succinate
(Catalog# : 1791516)
Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4)
104632-25-9 | Pramipexole HCl
(Catalog# : 1791510)
Pramipexole Dihydrochloride is an agonist of the Gαi-linked dopamine receptors D2, D
1435467-38-1 | PF-06281355
(Catalog# : 1791312)
PF-06281355, also known as PF-1355, is an orally available, selective and potent mech
1235481-43-2 | P7C3-OMe
(Catalog# : 179116)
P7C3-OMe, also known as (R)-P7C3-OMe, is an analogue of P7C3 and P3C3-A20. P7C3 Atten
1962928-21-7 | PF-CBP1 free base
(Catalog# : 179113)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
1817626-54-2 | PF-06650833
(Catalog# : 17988)
PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). RA
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib is an oral interleukin-2-inducible T cell kinase (ITK) inhibitor.
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration
2765081-21-6 | RMC-6236
(Catalog# : 25074)
Daraxonrasib, also known as RMC-6236 and RAS-IN-2, is a potent and selective RAS(ON)
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel