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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1821908-48-8 (free base) | SGC2085 free base
(Catalog# : 204609)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
164991-89-3 | Segetalin B
(Catalog# : 204501)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
1392816-46-4 | SI113
(Catalog# : 111896)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
1350643-72-9 | 3-[(1S)-1-aminoethyl]-8-chloro-2-phenyl-1,2-dihydroisoquinolin-1-one
(Catalog# : 196301)
186611-04-1 | SU 5214
(Catalog# : 19314)
SU 5214 is a modulator of tyrosine kinase signal transduction.
1423715-37-0 | Seclidemstat
(Catalog# : 192147)
Seclidemstat is an antineoplastic drug candidate.
1399715-48-0 | Setafrastat
(Catalog# : 192146)
Setafrastat is a rotamase inhibitor and vascular endothelial growth factor (VEGF) pro
1037210-93-7 | Saridegib
(Catalog# : 1812251)
Saridegib, also known as IPI-926, is an orally bioavailable, cyclopamine-derived inhi
1260612-13-2 | SAR260301
(Catalog# : 1812134)
SAR260301 is potent and selective Class I phosphatidylinositol-3-kinase (PI3K)β spec
1613695-14-9 | SGC-CBP30
(Catalog# : 1810244)
SGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are ge
1362850-20-1 | Seletalisib
(Catalog# : 1810221)
Seletalisib, also known as UCB-5857, is a potent and selective PI3 kinase inhibitor,
188817-13-2 | SC-560
(Catalog# : 185113)
SC-560 is a potent, orally active and selective inhibitor of COX-1.
1609452-30-3 | SEL120-34A HCl
(Catalog# : 18574)
SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high lev
1816294-67-3 | SR-4370
(Catalog# : 1842814)
SR-4370 is an HDAC inhibitor.
1821908-49-9 | SGC2085 HCl
(Catalog# : 184287)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
1222097-72-4 | S38093 HCl
(Catalog# : 184176)
S38093 is an inverse agonist at histamine H3 receptors.
1173022-21-3 | STO-609 acetate
(Catalog# : 184123)
STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases
1599441-71-0 | Super-TDU
(Catalog# : 18495)
Super-TDU is an inhibitory polypeptide targeting yap-teads interaction.
1253955-19-9 | (S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)methyl 2,4-dimethylbenzoate
(Catalog# : 183219)
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)met
132513-51-0 | (S)-Butyl 2-hydroxybutanoate
(Catalog# : 1712291)
butyl (2S)-2-hydroxybutanoate is building blocks.
14892-97-8 | SCR7 pyrazine
(Catalog# : 1712261)
SCR7 pyrazine is a small molecule inhibitor of DNA ligase IV that prevents nonhomolog
1333207-63-8 | SAR-7334 HCl
(Catalog# : 17101610)
SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that o
1160833-51-1 | SEN-826
(Catalog# : 1710168)
SEN-826 is a potential anticancer agent.
1366002-50-7 | Senexin A
(Catalog# : 1710136)
Senexin A is a potent and selective CDK8 inhibitor (IC50 = 280 nM). Senexin A binds t
1799633-27-4 | S63845
(Catalog# : 171071)
S63845 is a small molecule that specifically binds with high affinity to the BH3-bind
1105698-15-4 | Salermide
(Catalog# : 1791511)
Salermide is a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. S
1308672-74-3 | Sulfatinib
(Catalog# : 179135)
Sulfatinib is an orally bioavailable, small molecule inhibitor of vascular endothelia
101526-62-9 | Sematilide hydrochloride
(Catalog# : 179830)
Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective d
168835-82-3 | SU-1498
(Catalog# : 17984)
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEG
1174428-47-7 | SF2523
(Catalog# : 17918)
SF2523 is a highly selective and potent dual pan-PI3K/BRD4 inhibitor. SF2523 exhibits
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag