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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
1227637-23-1 | Tegatrabetan
(Catalog# : 192145)
Tegatrabetan, also known as Tegavivint and BC2059, is an orally bioavailable and pote
1359993-59-1 | Telratolimod
(Catalog# : 192144)
Telratolimod, also known as 3M-052 or MEDI-9197, is a toll-like receptor 7 (TLR-7) an
1260533-36-5 | TAS-116
(Catalog# : 191286)
TAS-116 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) subtypes
106635-81-8 | Tafenoquine succinate
(Catalog# : 191123)
Tafenoquine is being investigated as a potential treatment for malaria, as well as fo
106635-80-7 | Tafenoquine ( WR 238605 )
(Catalog# : 191122)
Tafenoquine is being investigated as a potential treatment for malaria, as well as fo
1558021-37-0 | TP0463518
(Catalog# : 1812282)
TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor. TP0463518
1009816-48-1 | Thiamet G
(Catalog# : 1812133)
Thiamet G is a potent and selective inhibitor of O-GlcNAcase.
1164462-05-8 | TG4-155
(Catalog# : 181232)
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less
123948-87-8 | Topotecan
(Catalog# : 1811212)
Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity.
1448169-71-8 | TAS-120
(Catalog# : 1811191)
TAS-120 is an orally bioavailable inhibitor of the fibroblast growth factor receptor
1038984-31-4 | Tulrampator ( CX-1632 )
(Catalog# : 1811161)
Tulrampator, also known as S-47445 and CX-1632, is a positive allosteric modulator (P
1226056-71-8 | Thiazovivin
(Catalog# : 1811122)
Thiazovivin is a selective, cell-permeable small molecule that inhibits ROCK activity
1862212-48-3 | TH 1217
(Catalog# : 1811021)
TH 1217 is a potent dCTP pyrophosphatase 1 inhibitor.
1137868-52-0 | TAK-960
(Catalog# : 18762)
TAK-960 is an orally available PLK1 inhibitor with potential antineoplastic activity.
1353644-70-8 | Theliatinib
(Catalog# : 186235)
Theliatinib, also known as HMPL-309, is a novel small molecule, epidermal growth fact
1616493-44-7 | Tucidinostat
(Catalog# : 186233)
Tucidinostat is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1
1111556-37-6 | Takinib
(Catalog# : 18672)
Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimula
1314890-29-3 | TMP269
(Catalog# : 185254)
TMP269 is a highly potent, selective and cell-permeable class IIa HDAC inhibitor with
1374743-00-6 | Trilaciclib (G1T28)
(Catalog# : 185235)
TRILACICLIB (G1T28), A HIGHLY POTENT, TRANSIENT CDK 4/6 INHIBITOR WITHIC50s OF 1 nM A
171235-71-5 | TAPI-1
(Catalog# : 185181)
TAPI-1 is and inhibitor of TACE. It inhibits the cleavage of TNF-a, TNFRI (p60), and
158899-10-6 | TLN-232
(Catalog# : 18594)
TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential ant
140194-24-7 | Triptorelin Acetate
(Catalog# : 18592)
Triptorelin is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the ac
1383816-29-2 | Tropifexor
(Catalog# : 18591)
Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment
1702809-17-3 | THZ531
(Catalog# : 184172)
THZ531 is a covalent CDK12 and CDK13 covalent inhibitor. Cyclin-dependent kinases 12
1802220-02-5 | TPX-0005
(Catalog# : 18423)
TPX-0005 is a Src/FAK/Janus kinase 2 (JAK2) inhibitor. TPX-0005 plus EGFR TKI suppres
1402601-82-4 | TUG-770
(Catalog# : 1791519)
TUG-770 is a Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatm
1429749-41-6 | Thiomyristoyl
(Catalog# : 1791113)
Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. IC50 &
1029877-94-8 | Trelagliptin succinate
(Catalog# : 179811)
Trelagliptin, also known as SYR-472, is a long acting dipeptidyl peptidase-4 (DPP-4)
1374516-07-0 | TUG-891
(Catalog# : 1783014)
TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR
1361951-15-6 | TP-3654
(Catalog# : 178303)
TP-3654 is a Pim-1 and Pim-3 kinase inhibitor potentially for the treatment of prosta
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag