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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
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JAK/STAT
MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Cas Index 2
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Cas Index 2
209783-80-2 | Entinostat
(Catalog# : 52607)
Entinostat (MS-275; SNDX 275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 M a
2740496-44-8 | FKL-117
(Catalog# : 24087)
2091769-17-2 | Fosmanogepix
(Catalog# : 24072)
Fosmanogepix is a novel antifungal, targeting the conserved Gwt1 enzyme required for
2417298-29-2 | FC-116
(Catalog# : 20569)
FC-116 is a Tubulin inhibitor that effectively inhibits tumor growth in mice.
2671128-05-3 | FHD-286
(Catalog# : 20471)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
2093305-05-4 | Fosgonimeton (ATH-1017)
(Catalog# : 1711225)
Fosgonimeton (ATH-1017) is a small molecule which enhance the activity of hepatocyte
2226521-65-7 | FM-381
(Catalog# : 20122201)
FM-381 is a Chemical Probe For JAK3 and JAK3 specific reversible covalent inhibitor.
2243736-45-8 | FB23-2
(Catalog# : 207102)
FB23-2 is a potent FTO inhibitor. FB23-2 demonstrated the potent inhibitory impact in
251577-09-0 | FTI-2148
(Catalog# : 111897)
FTI-2148 is a potent farnesyltransferase inhibitor with potential antitumor activity.
215589-63-2 | FR-190809
(Catalog# : 193253)
FR-190809 is a potent, nonadrenotoxic, orally efficacious ACAT inhibitor.
211735-76-1 | Farampator
(Catalog# : 179156)
Farampator, also known as Org-24448; CX-691, is an AMPA receptor positive allosteric
2698-69-3 | 4-FORMYL-2-METHOXY-3-NITROPHENYL ACETATE
(Catalog# : 178225)
4-FORMYL-2-METHOXY-3-NITROPHENYL ACETATE
223387-75-5 | FG-2216
(Catalog# : 16122812)
FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor
21679-14-1 | Fludarabine
(Catalog# : 021901)
Fludarabine, a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment
23110-15-8 | Fumagillin
(Catalog# : 122910)
Fumagillin is a complex biomolecule and used as an antimicrobial agent.
2369-11-1 | 5-Fluoro-2-nitroaniline
(Catalog# : 110216)
Coming soon!
25451-15-4 | Felbamate
(Catalog# : 52752)
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be r
2413455-99-7 | G-5758
(Catalog# : 24076)
2091134-68-6 | Golidocitinib ( AZD-4205 )
(Catalog# : 24028)
Golidocitinib (AZD-4205) is an oral JAK1 selective kinase inhibitor.
2657613-87-9 | Glecirasib
(Catalog# : 20672)
2648450-42-2 | GNE-7883
(Catalog# : 20589)
GNE-7883 is a pan-TEAD inhibitor.
2308520-97-8 | GLPG3667
(Catalog# : 20509)
GLPG3667 is an oral potent and selective small-molecule TYK2 inhibitor in development
2060571-02-8 | GDC-0077
(Catalog# : L20335)
Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-007
2507-91-7 | Gloxazone
(Catalog# : 20304)
Gloxazone is an effective but toxic anaplasmacide.
2407529-33-1 | Giredestrant tartrate
(Catalog# : 20263)
Giredestrant tartrate (GDC-9545 tartrate), a non-steroidal ER ligand, is an orally ac
2183470-12-2 | GCN2iB
(Catalog# : 2071802)
GCN2iB is an ATP-competitive GCN2 inhibitory compound with a better pharmacokinetic p
2101626-26-8 | GSK2894631A
(Catalog# : 2071528)
GSK2894631A is a hematopoietic PGD synthase (HPGDS) inhibitor.
2361659-62-1 | GSK8612
(Catalog# : 2071527)
GSK8612 is a potent and highly selective TBK1 inhibitor. GSK8612 inhibited recombinan
2049868-46-2 | GSK-963
(Catalog# : 193185)
GSK-963, also known as GSK'963 or GSK963, is a potent and selective inhibitor of
2138814-32-9 | GSK3004774
(Catalog# : 192281)
GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag