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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Cas Index 2
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Cas Index 2
2227304-19-8 | CP-506 ( Synonyms: SN-36506 )
(Catalog# : 20645)
CP-506 (SN-36506) is an hypoxia-activated prodrug of a DNA-alkylating nitrogen mustar
209986-17-4 | Compound E
(Catalog# : 20575)
Compound E is a cell-permeable, potent, selective inhibitor of ɣ-secretase and Notch
20217-22-5 | COH1 inhibitor
(Catalog# : 20555)
COH1 is a ribonucleotide reductase (RR) inhibitor.
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
218457-67-1 | CB-103
(Catalog# : 20322)
CB-103 is a γ-secretase inhibitor. CB-103 inhibits Notch signaling in primary human
2316817-88-4 | CB-6644
(Catalog# : 41788)
CB-6644 acts as a noncompetitive ATPase inhibitor. Additionally, it can inhibit RUVBL
21815-91-8 | 3-chloro-1-benzothiophene-2-carbonyl chloride
(Catalog# : 2062306)
23982-76-5 | 10-Cl-BBQ
(Catalog# : 1810161)
10-Cl-BBQ is an aryl hydrocarbon receptor (AhR) ligand.
218600-44-3 | CDDO
(Catalog# : 92304)
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of induc
282526-98-1 | Cetilistat
(Catalog# : 16122918)
Cetilistat, also known as ATL-962, is a drug designed to treat obesity. It acts in th
289499-45-2 | Canertinib
(Catalog# : 16122909)
Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quina
28755-03-5 | 3 CAI
(Catalog# : 611801)
3CAI is a potent allosteric and specific AKT inhibitor, which exerts efficacy in vitr
252917-06-9 | CHIR-99021
(Catalog# : 16062904)
CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor t
252935-94-7 | CHIR-98014
(Catalog# : 5121103)
CHIR98014 is a reversible, cell-permeable activator of the WNT pathway, through inhib
267243-28-7 | Canertinib
(Catalog# : 120109)
Canertinib is an orally bioavailable irreversible Pan-erbB tyrosine kinase inhibitor,
202591-23-9 | CPI-203
(Catalog# : 110605)
CPI203 is a novel potent, selective and cell permeable inhibitor of the bromodomain a
200484-11-3 | CHS-828
(Catalog# : 100904)
CHS-828, also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 i
2019-34-3 | 3-(4-Chlorophenyl)propanoic acid
(Catalog# : 90615)
Coming soon!
288383-20-0 | Cediranib
(Catalog# : 52779)
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, al
285986-88-1 | CCG-1423
(Catalog# : 52502)
CCG-1423 is a novel inhibitor of RhoA/C-mediated gene transcription that is capable o
2230198-02-2 | Danuglipron
(Catalog# : 20538)
Danuglipron, also known as PF-06882961 is a potent, orally bioavailable agonist of th
2413428-36-9 | DSN28369
(Catalog# : 20498)
DSN28369 is a heterobifunctional linker, and useful to make antibody drug conjuate (A
2105905-46-0 | 4,6-dichloro-1H-pyrazolo[3,4-b]pyridine
(Catalog# : 20434)
2407725-14-6 | 4,6-dimethylpyrazolo[1,5-a]pyrazine-2-carbaldehyde
(Catalog# : 20361)
2413256-25-2 | Difelikefalin HCl
(Catalog# : 21922)
Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is a novel and potent kappa opio
2138299-34-8 | diABZI STING agonist-1 trihydrochloride
(Catalog# : 2112802)
2365172-42-3 | DT-2216
(Catalog# : 20111802)
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chim
2007975-22-4 | DSR-141562
(Catalog# : 20792)
DSR-141562 is novel Phosphodiesterase 1 Inhibitor for the Treatment of Positive Sympt
24241-18-7 | 3,5-dibromopyrazin-2-amine
(Catalog# : 2062016)
2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neu
290304-24-4 | Daun02
(Catalog# : 18793)
Daun02 is a Cell viability inhibitor and DNA synthisis inhibitor with IC50 values of
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!