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PI3K/Akt/mTOR
Epigenetics
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Apoptosis
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Immunology & Inflammation
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PROTAC
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Cas Index 2
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Cas Index 2
2416874-75-2 | KB-0742 dihydrochloride
(Catalog# : 24020)
KB-0742 is a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9
2082765-42-0 | KP-302 ( Synonyms: Lucid-21-302 ; Lucid-MS )
(Catalog# : 20641)
KP-302 ( Synonyms: Lucid-21-302 ; Lucid-MS ) is a small molecule inhibitor of protein
2446480-97-1 | KSQ-4279
(Catalog# : 20472)
KSQ-4279 is a USP1 and PARP inhibitor. KSQ-4279 showed anti-proliferative effects in
2226664-93-1 | KY19382
(Catalog# : L20334)
KY19382 is an orally active dual inhibitor of CXXC5-DVL and GSK3β
228559-41-9 | Ki8751
(Catalog# : 17022703)
Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). D
286370-15-8 | KRN 633
(Catalog# : 51912)
KRN 633 is an ATP-competitive inhibitor ofVEGFR1/2/3withIC50of 170 nM/160 nM/125 nM,
2688040-45-9 | Lirafugratinib HCl
(Catalog# : 24113)
Lirafugratinib, also known as RLY-4008, is a tyrosine kinase inhibitor with potential
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2834106-06-6 | LTGO-33
(Catalog# : 24103)
LTGO-33 is a selective, state-independent, and potent preclinical small molecule NaV1
2719793-90-3 | Lunresertib
(Catalog# : 24080)
Lunresertib, alsop known as RP-6306, is a potent and selective PKMYT1 inhibitor (IC50
2495096-26-7 | lartesertib
(Catalog# : 24066)
Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM (ext
297180-15-5 | Lipofermata
(Catalog# : 24030)
Lipofermata is a fatty acid transport protein 2(FATP2)inhibitor. Lipofermata shows fa
2568608-48-8 | LY3522348
(Catalog# : 20577)
244240-24-2 | LFM-A13
(Catalog# : 20438)
LFM-A13 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). LF
2375815-63-5 | LY-3475070
(Catalog# : 21244)
LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alo
2097938-59-3 | Lerociclib HCl (G1T38 HCl)
(Catalog# : 2073106)
Lerociclib HCl (G1T38)is a novel, selective,differentiated oral CDK4/6 inhibitor with
2055050-87-6 | LAU159
(Catalog# : 2071505)
LAU159 is a potent modulator of α6β3γ2 GABAA receptor.
294623-49-7 | L006235
(Catalog# : 2061307)
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays
2274819-46-2 | LUT-014
(Catalog# : 2042701)
LUT-014 is a B-Raf Inhibitor. Leveraging the paradoxical effect of B-Raf Inhibitors,
2135600-76-7 | LSZ102
(Catalog# : 2041502)
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50
2173037-97-1 | LY2794193
(Catalog# : 193262)
LY2794193 is a highly potent and selective mGlu3 receptor agonist.
2166616-75-5 | LY-3381916
(Catalog# : 193123)
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, bi
245075-84-7 | LR-90
(Catalog# : 19364)
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory res
2222755-14-6 | LOXO-292
(Catalog# : 192195)
LOXO-292 (ARRY-192) is an oral and selective investigational drug in clinical develop
292632-98-5 | L685458
(Catalog# : 186156)
L685458 is a potent and selective γ -secretase inhibitor.
2097002-61-2 | LOXO-195
(Catalog# : 185212)
LOXO-195 is a potent and selective TRK inhibitor capable of addressing potential mech
2088939-99-3 | LYN-1604
(Catalog# : 18493)
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, a
226929-39-1 | LB42708
(Catalog# : 18443)
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhi
2040291-27-6 | LLY-283
(Catalog# : 184314)
LLY-283 is a potent and selective SAM-competitive chemical probe for PRMT5.
231277-92-2 | Lapatinib
(Catalog# : 17022807)
Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 n
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.
98570-83-3 | Phylloflavan
(Catalog# : 24155)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW