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PI3K/Akt/mTOR
Epigenetics
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Apoptosis
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
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PROTAC
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Cas Index 2
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Cas Index 2
2097002-61-2 | LOXO-195
(Catalog# : 185212)
LOXO-195 is a potent and selective TRK inhibitor capable of addressing potential mech
2088939-99-3 | LYN-1604
(Catalog# : 18493)
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, a
226929-39-1 | LB42708
(Catalog# : 18443)
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhi
2040291-27-6 | LLY-283
(Catalog# : 184314)
LLY-283 is a potent and selective SAM-competitive chemical probe for PRMT5.
231277-92-2 | Lapatinib
(Catalog# : 17022807)
Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 n
27262-47-1 | Levobupivacaine free base
(Catalog# : 16123031)
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is
2070014-90-1 | LY 303511 hydrochloride
(Catalog# : 611819)
LY303511 Hcl, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhi
253863-00-2 | L-778123 hydrochloride
(Catalog# : 121805)
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and
248281-84-7 | Laquinimod
(Catalog# : 121506)
Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva.
244240-24-2 | LFM-A13
(Catalog# : 52206)
Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits poli
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
2891709-58-1 | MS6105
(Catalog# : 25039)
2763252-25-9 | M3554
(Catalog# : 25017)
M3554, a novel anti-GD2 antibody drug conjugate.
2990506-75-5 | ML353
(Catalog# : 24151)
ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM).
2101538-28-5 | 2-MNG
(Catalog# : 24129)
2-MNG is an inhibitor for melanogenesis with an average IC50 of 49.5μM. 2-MNG alone
2630904-45-7 | MRTX1719
(Catalog# : 262401)
MRTX1719 is a potent and selective binder to the PRMT5•MTA complex and selectively
2326521-71-3 | MRTX849
(Catalog# : 20611)
Adagrasib, also known as MRTX849, is a potent, highly selective, oral available KRAS
2377352-49-1 | Migoprotafib
(Catalog# : 20592)
Migoprotafib, also known as GDC-1971 and RLY-1971, is a SHP2 allosteric inhibitor. GD
2861190-30-7 | Mtb-IN-2
(Catalog# : 20572)
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis
2565656-70-2 | muvalaplin
(Catalog# : 20528)
2747162-85-0 | MCUF-651
(Catalog# : 20470)
MCUF-651 is a small molecule guanylyl cyclase A receptor positive allosteric modulato
2654743-22-1 | MRTX0902
(Catalog# : 171462)
MRTX0902is a potent SOS1 inhibitor which can be used for the therapeutic intervention
210113-85-2 | methyl 4-(2-aminoethoxy)benzoate hydrochloride
(Catalog# : 20407)
235748-94-4 | methyl (3-chloropyrazin-2-yl)acetate
(Catalog# : 20395)
2385682-18-6 | methyl 3-bromo-4-ethoxy-5-formylbenzoate
(Catalog# : 20364)
24589-99-9 | Methyl 3-formyl-4-hydroxybenzoate
(Catalog# : 20362)
2621928-55-8 | MRTX1133
(Catalog# : 20291)
MRTX1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12
2416417-65-5 | MYF-01-37
(Catalog# : 20261)
MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with
2144491-78-9 | MUN91789
(Catalog# : 21245)
MUN91789, also known as CPD77, is a potent inhibitor of SARS-CoV-2 main protease. MUN
2379438-80-7 | MVN38807
(Catalog# : 21243)
MVN38807, also known as Y-1, is neuraminidase (NA) inhibitor used in preparation of d
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1198078-60-2 | NT219
(Catalog# : 25067)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
858128-57-1 | SPB linker
(Catalog# : 25066)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
1404380-58-0 | JTE-151
(Catalog# : 20594)
JTE-151 is a novel RORγ inverse agonist.
112108-01-7 | Ecopipam ( SCH 39166 )
(Catalog# : 25065)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the