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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 2
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Cas Index 2
257933-82-7 | Pelitinib
(Catalog# : 17022702)
Pelitinib (EKB-569; WAY-EKB 569) is a potent irreversible EGFR inhibitor with IC50 of
202350-68-3 | PNU-159682
(Catalog# : 16071409)
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsom
269718-84-5 | Pardoprunox
(Catalog# : 122523)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
219580-11-7 | PD173074
(Catalog# : 122212)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
269718-83-4 | Pardoprunox hydrochloride
(Catalog# : 111010)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
20062-91-3 | 3-(4-phenoxyphenyl)propanoic acid
(Catalog# : 90709)
Coming soon!
212844-53-6 | Purvalanol A
(Catalog# : 52564)
Purvalanol A(NG-60) is a potent, cell-permeable, and selective inhibitor of cyclin-de
212844-54-7 | Purvalanol B
(Catalog# : 52559)
Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6,
2645-32-1 | PR-619
(Catalog# : 52227)
PR-619 is a broad-range DUB inhibitor with potential for further development as a che
2642037-07-6 | RMC-4998
(Catalog# : 20666)
RMC-4998 is a tri-complex inhibitor and KRASG12C inhibitor. RMC-4998 targets the acti
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
2750709-91-0 | Resigratinib
(Catalog# : 20627)
Resigratinib is a fibroblast growth factor receptor tyrosine kinase inhibitor and ant
2031185-00-7 | Risvodetinib
(Catalog# : 20621)
Risvodetinib, also known as IkT-148009., is a brain-penetrant c-Abl inhibitor with a
2366152-15-8 | RPT193
(Catalog# : 20526)
2192215-81-7 | Ritlecitinib tosylate
(Catalog# : 20452)
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF
2171386-10-8 | RK-287107
(Catalog# : 2071520)
RK-287107 is a potent TNKS/TNKS2 inhibitor (IC50 = 14.4 nM) with >7000-fold select
2381037-82-5 | RBN-2397
(Catalog# : 207101)
2161337-98-8 | (2R,6S)-tert-butyl 4-(4-aminobenzoyl)-2,6-dimethylpiperazine-1-carboxylate
(Catalog# : 2062334)
243984-11-4 | Resatorvid
(Catalog# : 206102)
Resatorvid, also known as TAK-242, is a cell-permeable inhibitor of TLR4 signaling, b
2262452-06-0 | RU320521
(Catalog# : 204503)
RU320521, also known as RU521; RU.521 is a potent and selective inhibitor of cGAS, in
2086689-88-3 | (R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate
(Catalog# : 580586)
(R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate, CAS 2086689-88-3, is a v
2072057-17-9 | RG7834
(Catalog# : 19355)
RG7834,also known as RO7020322, is a novel oral HBV viral gene expression inhibitor
252889-88-6 | RWJ-56110
(Catalog# : 19353)
RWJ-56110 is a selective protease-activated receptor-1 (PAR1) antagonist. It blocks t
259188-38-0 | Rebimastat
(Catalog# : 192254)
Rebimastat, also known as BMS275291, is a sulfhydryl-based second-generation matrix m
2172651-73-7 | RMC-4550
(Catalog# : 186251)
RMC-4550 is a potent and selective SHP2 inhibitor.
2133832-83-2 | R-IMPP
(Catalog# : 18413)
R-IMPP is an inhibitor of PCSK9 translation.
2003234-63-5 | R-GNE-140
(Catalog# : 18432)
R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDH
2097334-19-3 | (2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183217)
(2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopr
2097334-18-2 | (R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183216)
(R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate is a
269730-03-2 | RPI-1
(Catalog# : 17030301)
RPI-1 is an ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused grow
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag