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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Anilines
Boronic Acids
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Cas Index 2
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Cas Index 2
2055757-40-7 | SHP394
(Catalog# : 193122)
SHP394 is a potent and orally active SHP2 inhibitor (IC50 = 23 nM) with high lipophil
2226517-76-4 | SGC-GAK-1
(Catalog# : 193113)
SGC-GAK-1 is a potent and selective GAK kinase probe which targets the ATP-binding si
2152628-33-4 | Selpercatinib
(Catalog# : 192276)
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties.
254740-64-2 | Sparsentan
(Catalog# : 1812132)
Sparsentan, also known as RE-021, PS433540 and DARA-a, is a Dual angiotensin II and e
205678-31-5 | SB-273005
(Catalog# : 186221)
SB-273005 is an inhibitor of integrin αvβ3.
2097334-20-6 | (S)-3-(tert-butoxycarbonyl)-2-(4-((2,4-dimethylbenzoyloxy)methyl)phenyl)propanoic acid
(Catalog# : 183218)
(S)-3-(tert-butoxycarbonyl)-2-(4-((2,4-dimethylbenzoyloxy)methyl)phenyl)propanoic aci
2070015-26-6 | SRT3025 HCl
(Catalog# : 17101310)
SRT3025 is an orally available small molecule activator of the SIRT1 enzyme.
271576-80-8 | SD-06
(Catalog# : 1791320)
SD-06 is a MAPK p38 alpha inhibitor for the treatment of arthritis.
215543-92-3 | SU5402
(Catalog# : 174191)
SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibit
201677-61-4 | Sivelestat sodium
(Catalog# : 16122758)
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhib
2070015-29-9 | SJB3-019A
(Catalog# : 611930)
SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 ti
280744-09-4 | SB-216763
(Catalog# : 161009026)
SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse
287383-59-9 | Scriptid
(Catalog# : 16071007)
Scriptid
223104-29-8 | SEA0400
(Catalog# : 16070911)
SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxic
211110-63-3 | Sobetirome
(Catalog# : 16070907)
Sobetirome, also known as GC-1 and QRX-431, is a hyroid hormone beta-receptor agonist
264218-23-7 | SB 415286
(Catalog# : 010425)
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3
2185-03-7 | (3S)-3-aminooxolan-2-one,hydrochloride
(Catalog# : 120804)
Coming soon!
292605-14-2 | SB-3CT
(Catalog# : 110220)
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor, which is a 2-[
224177-60-0 | Siramesine hydrochloride
(Catalog# : 52549)
Siramesine(Lu 28-179) Hcl is a selective sigma-2 receptor agonist, which has been sho
218156-96-8 | SRPIN340
(Catalog# : 52210)
SRPIN340 is a serine/arginine-rich protein kinase (SRPK)-specific inhibitor with an I
204005-46-9 | Semaxanib (SU5416)
(Catalog# : 51803)
Semaxanib (SU5416) is a potent and selectiveVEGFR(Flk-1/KDR) inhibitor withIC50of 1.2
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
2319722-53-5 | TM5441sodium
(Catalog# : 24149)
TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhi
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
2800223-30-5 | TYRA-300
(Catalog# : 24073)
TYRA-300 is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the Treatment of Uro
2559759-04-3 | tambiciclib dimaleate
(Catalog# : 24071)
2653254-31-8 | TYA-018
(Catalog# : 20667)
TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2760481-53-4 | TNG908
(Catalog# : 20646)
TNG908 is a clinical stage MTA-cooperative PRMT5 inhibitor that is selectively active
2567459-64-5 | Tilpisertib Fosmecarbil
(Catalog# : 20598)
Tilpisertib fosmecarbil is a potent serine/threonine kinase inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1198078-60-2 | NT219
(Catalog# : 25067)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
858128-57-1 | SPB linker
(Catalog# : 25066)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
1404380-58-0 | JTE-151
(Catalog# : 20594)
JTE-151 is a novel RORγ inverse agonist.
112108-01-7 | Ecopipam ( SCH 39166 )
(Catalog# : 25065)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the