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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Cas Index 2
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Cas Index 2
212141-54-3 | Vatalanib
(Catalog# : 010434)
Vatalanib free base is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent aga
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
2229025-70-9 | WM 3835
(Catalog# : 20504)
WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. It reduces H3K14ac level
2253985-29-2 | WK500B
(Catalog# : 20491)
WK500B is a BCL6 inhibitor. WK500B engaged BCL6 inside cells, blocked BCL6 repression
2055397-28-7 | WM-1119
(Catalog# : 181181)
WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A wit
211555-05-4 | WHI-P97
(Catalog# : 185710)
WHI-P97 is a JAK3 inhibitor.
214358-33-5 | 1400W
(Catalog# : 17021321)
1400W is a slow, tight binding, and highly selective inhibitor ofinducible nitric-oxi
2012607-27-9 | WNK463
(Catalog# : 6111509)
WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activi
211555-04-3 | WHI-P154
(Catalog# : 73107)
WHI-P 154 is a JAK3 inhibitor (IC50 = 1.8 M) that displays no activity at JAK1 or JAK
211555-08-7 | WHI-P180
(Catalog# : 52221)
WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respective
2700286-66-2 | XPW1
(Catalog# : 20659)
XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear c
2367004-54-2 | XL092
(Catalog# : 20506)
XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and
2061980-01-4 | XMU-MP-1
(Catalog# : 18579)
XMU-MP-1 is a potent and selective MST1/2 inhibitor.
284028-89-3 | XAV-939
(Catalog# : 52632)
XAV939 is a small molecule and selective Wnt pathway -catenin-mediated transcription
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
2863670-67-9 | YCT529
(Catalog# : 24120)
YCT529, an RAR-α inhibitor, is used as a contraceptive, with a 99% effectiveness. YC
2064269-82-3 | YK-029A
(Catalog# : 20670)
2131223-85-1 | YW2065
(Catalog# : 20494)
YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achi
2226534-49-0 | Y06137
(Catalog# : 193193)
Y06137 is a potent and selective BET inhibitor, which binds to the BRD4(1) bromodomai
223499-30-7 | YM-58483 (BTP2)
(Catalog# : 17109009)
YM-58483/BTP2 is a blocker of store-operated Ca2+ entry (SOCE), which regulates the a
288250-47-5 | Y-320
(Catalog# : 52516)
Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD
2306303-35-3 | ZINC20451377
(Catalog# : 24132)
ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) wi
210345-04-3 | Z-LEHD-FMK
(Catalog# : 24127)
Z-LEHD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-9. Z-LE
210344-98-2 | Z-IETD-FMK
(Catalog# : 24126)
MDK4982, also known as Z-IETD-FMK, is a potent, cell-permeable, irreversible inhibito
210344-95-9 | Z-DEVD-fmk
(Catalog# : 24125)
Z-DEVD-fmk is a cell-permeable, irreversible inhibitor of caspase-3. Caspase-3 is a c
2133852-18-1 | Zastaprazan
(Catalog# : 24123)
Zastaprazan, also known as JP-1366, is a proton pump inhibitor. JP-1366 mediates stro
2403703-30-8 | Zurletrectinib
(Catalog# : 24104)
Zurletrectinib is a tyrosine kinase inhibitor with potential as an antineoplastic age
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2891709-58-1 | INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002)
2247396-91-2 | HC-5404
(Catalog# : 25001)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.
98570-83-3 | Phylloflavan
(Catalog# : 24155)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW