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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
Building Blocks
Aldehydes
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
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Ordering
Contact Us
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index A
A-1210477
(Catalog# : 17022404, Cas# :
1668553-26-1
)
A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks
Apatinib
(Catalog# : 17022301, Cas# :
811803-05-1
)
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
Amikacin sulfate
(Catalog# : 17021407, Cas# :
39831-55-5
)
Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic der
AFN-1252
(Catalog# : 17021406, Cas# :
620175-39-5
)
AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (F
AZD3293 (LY3314814)
(Catalog# : 17021318, Cas# :
1383982-64-6
)
AZD3293, also known as LY3314814 is an oral beta-secretase 1 cleaving enzyme (BACE)
APR-246 (PRIMA-1MET)
(Catalog# : 17021316, Cas# :
5291-32-7
)
APR-246, also known as PRIMA-1MET, is a small organic molecule that has been shown to
AZD-8835
(Catalog# : 102703, Cas# :
1620576-64-8
)
AZD8835 is a potent and selective inhibitor of PI3Kalpha and PI3Kdelata with excellen
AZD6482 (S-isomer)
(Catalog# : 17011901, Cas# :
1173900-37-2
)
AZD6482 is a potent, selective and ATP competitive PI3K inhibitor (IC(50) 0.01 μm).
7ACC2
(Catalog# : 17011302, Cas# :
1472624-85-3
)
7ACC2 is a potent MCT inhibitor. Monocarboxylate transporters (MCTs) catalyze the pro
AZD-5597
(Catalog# : 16122865, Cas# :
924641-59-8
)
AZD-5597 is potent CDK inhibitor with in vitro anti-proliferative effects against a r
AZD-5069
(Catalog# : 16122864, Cas# :
878385-84-3
)
AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neu
AZD-2461
(Catalog# : 16122863, Cas# :
1174043-16-3
)
AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. A
Avitinib maleate
(Catalog# : 16122862, Cas# :
1557268-88-8
)
Avitinib is an orally available, irreversible, epidermal growth factor receptor (EGFR
Avibactam sodium
(Catalog# : 16122861, Cas# :
1192491-61-4
)
Avibactam is a non--lactam -lactamase inhibitor antibiotic, which is a new drug appli
Avatrombopag
(Catalog# : 16122860, Cas# :
570406-98-3
)
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-ac
Atorvastatin calcium trihydrate
(Catalog# : 16122859, Cas# :
344423-98-9
)
Atorvastatin is used primarily for lowering blood cholesterol and for prevention of e
Argatroban
(Catalog# : 16122858, Cas# :
141396-28-3
)
Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was ap
Amiselimod HCl
(Catalog# : 16122856, Cas# :
942398-84-7
)
Amiselimod, also known as MT1303, is a potent and selective immunosuppressant and sph
AM-2394
(Catalog# : 16122855, Cas# :
1442684-77-6
)
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phos
Alvelestat (AZD9688)
(Catalog# : 16122854, Cas# :
848141-11-7
)
Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (
Alpha-Mangostin
(Catalog# : 16122802, Cas# :
6147-11-1
)
Alpha-Mangostin is a natural xanthonoid, a type of organic compound isolated from var
Aloxistatin (E-64d)
(Catalog# : 16122801, Cas# :
88321-09-9
)
Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autoph
Alanosine
(Catalog# : 161227117, Cas# :
5854-93-3
)
Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derive
Afuresertib HCl
(Catalog# : 161227116, Cas# :
1047645-82-8
)
Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the ser
ACY-738
(Catalog# : 161227114, Cas# :
1375465-91-0
)
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability
Acolbifene
(Catalog# : 161227113, Cas# :
182167-02-8
)
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modu
Abametapir
(Catalog# : 161227111, Cas# :
1762-34-1
)
Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metallopro
Alantolactone
(Catalog# : 161227107, Cas# :
546-43-0
)
Alantolactone, a naturally occurring eudesmane-type sesquiterpene lactone (SL), could
AS101
(Catalog# : 161227106, Cas# :
106566-58-9
)
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1bet
ACP-196
(Catalog# : 16122783, Cas# :
1420477-60-6
)
Acalabrutinib is a selective second-generation Brutons tyrosine kinase (BTK) inhibito
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag