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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Custom Synthesis
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Name Index A
AZD-0284
(Catalog# : 19365, Cas# :
2101291-07-8
)
AZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for th
AZ304
(Catalog# : 19363, Cas# :
942507-42-8
)
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type B
AZ876
(Catalog# : 19356, Cas# :
898800-26-5
)
AZ876, also known as AZ-876, is a liver X receptor agonist. AZ876 protects against pa
AGN-190299
(Catalog# : 19316, Cas# :
118292-41-4
)
Tazarotene is a retinoid prodrug which is converted to its active form, the cognate c
AM281
(Catalog# : 19315, Cas# :
202463-68-1
)
AM281 is a synthetic cannabinoid CB1 receptor antagonist.
ASP9521
(Catalog# : 19312, Cas# :
1126084-37-4
)
ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid d
AZD0364
(Catalog# : 192275, Cas# :
2097416-76-5
)
AZD0364 is an ERK1 and/or ERK2 kinase for the treatment of cancer. ERK1 and ERK2 kina
ATF6-activator-147
(Catalog# : 192212, Cas# :
393121-74-9
)
ATF6-activator-147 is an ATF6 simulator which acts as a prodrug that preferentially t
AZD1152
(Catalog# : 192156, Cas# :
722543-31-9
)
AZD1152 is a pro-drug of Barasertib-hQPA, which is a highly selective Aurora B inhibi
AZD3229
(Catalog# : 191287, Cas# :
2248003-60-1
)
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal st
AM095 sodium
(Catalog# : 191251, Cas# :
1345614-59-6
)
AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chi
AZD4573 free base
(Catalog# : 191212, Cas# :
2057509-72-3
)
AZD-4573 is a selective, short-acting inhibitor of the serine/threonine cyclin-depend
AR-9281
(Catalog# : 191146, Cas# :
913548-29-5
)
AR-9281 is a soluble epoxide hydrolase (s-EH) inhibitor potentially for the treatment
ARRY-797 (ARRY-371797)
(Catalog# : 191112, Cas# :
1036404-17-7
)
ARRY-797 is an oral, selective p38 mitogen-activated protein kinase inhibitor. ARRY-7
Abivertinib
(Catalog# : 19141, Cas# :
1557267-42-1
)
Abivertinib, also known as AC0010 and Avitinib, is a tyrosine kinase inhibitor, antin
AZD7507
(Catalog# : 1812294, Cas# :
1041852-85-0
)
AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is
Auranofin
(Catalog# : 1812281, Cas# :
34031-32-8
)
Auranofin, also known as Ridaura and SKF-39162, is an oral chrysotherapeutic agent fo
AX-024 HCl
(Catalog# : 181254, Cas# :
1704801-24-0
)
AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively i
AG 879
(Catalog# : 1811303, Cas# :
148741-30-4
)
AG-879 is a tyrphostin compound that inhibits nerve growth factor-dependent TrkA tyro
Avagacestat
(Catalog# : 1811283, Cas# :
1146699-66-2
)
Avagacestat, also known as BMS-708163, is an oral GSI designed for selective inhibiti
AS1842856
(Catalog# : 1811265, Cas# :
836620-48-5
)
AS1842856 is a cell-permeable Foxo1inhibitor that blocks the transcription activity o
Anlotinib HCl ( AL-3818 )
(Catalog# : 1811211, Cas# :
1360460-82-7
)
Anlotinib is a novel oral tyrosine kinase inhibitor (TKI) targeting c-kit, platelet-d
Avatrombopag maleate
(Catalog# : 5141902, Cas# :
677007-74-8
)
Avatrombopag maleate is an orally bioavailable, small molecule thrombopoietin recepto
AZD-3514
(Catalog# : 1810251, Cas# :
1240299-33-5
)
AZD-3514 is a potent androgen receptor downregulator with potential anticancer cancer
AZ32
(Catalog# : 1810223, Cas# :
no
)
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with
ARS-1620
(Catalog# : 1810222, Cas# :
1698055-85-4
)
ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokin
AGL-2263
(Catalog# : 1810175, Cas# :
638213-98-6
)
AGL-2263 is a novel insulin receptor inhibitor.
AM211
(Catalog# : 1810173, Cas# :
1175526-27-8
)
AM-211 is a novel and potent antagonist of the prostaglandin D2 receptor type 2.
Arimoclomol maleate
(Catalog# : 188281, Cas# :
289893-26-1
)
Arimoclomol, also known as BRX-220, is potentially useful for the treatment of Nieman
ASP7663
(Catalog# : 187123, Cas# :
1190217-35-6
)
ASP7663 is an orally bioavailable selective TRPA1 activator.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag