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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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PROTAC
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
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Sulfonamides
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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Name Index A
APS-2-79
(Catalog# : 16122775, Cas# :
2002381-31-7
)
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antago
Aprotinin
(Catalog# : 16122761, Cas# :
9087-70-1
)
Aprotinin is a small protein serine protease inhibitor, used to reduce perioperative
A-366
(Catalog# : 16122743, Cas# :
1527503-11-2
)
A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor wi
AZD0156
(Catalog# : 16122713, Cas# :
1821428-35-6
)
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/rad
APTSTAT3-9R
(Catalog# : 16122704)
APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating m
AGN 205728
(Catalog# : 6111520, Cas# :
859498-05-8
)
AGN 205728 is a potent and selective RAR antagonist with Ki/IC95 values of 3 nM/ 0.6
AGN 205327
(Catalog# : 6111519)
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RAR// r
AGN 195183
(Catalog# : 6111517, Cas# :
367273-07-2
)
AGN 195183 is a potent and selective agonist of RAR(Kd=3 nM) with improved binding se
AGN 194310
(Catalog# : 6111516, Cas# :
229961-45-9
)
AGN 194310(VTP-194310) is a potent and selective pan-RARs agonist with Kd values of 3
Acetazolamide D3
(Catalog# : 6111513, Cas# :
1189904-01-5
)
Acetazolamide D3 is deuterium labeled Acetazolamide, which is a potent carbonic anhyd
APS-2-79
(Catalog# : 6111501, Cas# :
2002381-25-9
)
APS-2-79 is an antagonist of MEK phosphorylation by RAF through direct binding of the
(+)-Apogossypol
(Catalog# : 61125, Cas# :
66389-74-0
)
(+)-Apogossypol(Apogossypol; NSC736630) is a potent inhibitor of Bcl-2 family protein
A-836339
(Catalog# : 6111107, Cas# :
959746-77-1
)
A-836339 is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at
AB-MECA
(Catalog# : 6111105, Cas# :
152918-26-8
)
AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recom
Amitifadine hydrochloride
(Catalog# : 6111104, Cas# :
410074-74-7
)
Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinep
ATI-2341
(Catalog# : 6111101, Cas# :
1337878-62-2
)
ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allos
Auristatin F
(Catalog# : 6111022, Cas# :
163768-50-1
)
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor acti
Auristatin E
(Catalog# : 6111021, Cas# :
160800-57-7
)
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor acti
ABT-639
(Catalog# : 6111011, Cas# :
1235560-28-7
)
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-6
3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile
(Catalog# : 6111001, Cas# :
21230-50-2
)
3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile 21230-50-2
360A
(Catalog# : 611935, Cas# :
794458-56-3
)
360A is a strong affinity and selectivity inhibitor of G-quadruplex structures.
AT7519 trifluoroacetate
(Catalog# : 611916, Cas# :
1431697-85-6
)
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of
Ampkinone
(Catalog# : 611810, Cas# :
1233082-79-5
)
Ampkinone is a small molecule activator of AMPK; stimulate functional activation of A
AT7867 dihydrochloride
(Catalog# : 611806, Cas# :
1431697-86-7
)
AT7867 Hcl is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50
ARQ-092
(Catalog# : 611805, Cas# :
1313881-70-7
)
ARQ-092 is an Akt inhibitor extracted from patent US/20150299195A1, compound A.
Akt1 and Akt2-IN-1
(Catalog# : 611804, Cas# :
893422-47-4
)
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50
AKT inhibitor
(Catalog# : 611803, Cas# :
1004990-28-6
)
AKT inhibitor is a broadly selective, potent, ATP-competitive Akt inhibitor, displays
A-674563 hydrochloride
(Catalog# : 611802, Cas# :
2070009-66-2
)
A-674563 hydrochloride is a potent selective Akt1 inhibitor with an IC50 of 14 nM; al
Avasimibe
(Catalog# : 161014003, Cas# :
166518-60-1
)
Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasi
Apoptozole
(Catalog# : 161014002, Cas# :
1054543-47-3
)
Apoptosis Activator VII, Apoptozole is a cell-permeable imidazole compound that direc
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag