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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
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Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
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Pyrimidines
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On Sale
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Ordering
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About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
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Name Index A
Amuvatinib
(Catalog# : 123016, Cas# :
850879-09-3
)
Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC5
AR-42
(Catalog# : 123009, Cas# :
935881-37-1
)
AR-42 is a novel, oral cancer therapy currently in early clinical development.
A-966492
(Catalog# : 123006, Cas# :
934162-61-5
)
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 n
AMG 487
(Catalog# : 122942, Cas# :
473719-41-4
)
AMG 487 is a small molecule antagonist of the chemokine receptor CXCR3.
Atosiban acetate
(Catalog# : 122931, Cas# :
90779-69-4
)
Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/
AST-1306
(Catalog# : 122926, Cas# :
897383-62-9
)
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and
AZD8186
(Catalog# : 122925, Cas# :
1627494-13-6
)
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K
AG-120
(Catalog# : 122906, Cas# :
1448346-63-1
)
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), wi
AZD-5423
(Catalog# : 122902, Cas# :
1034148-04-3
)
Coming soon!
A 83-01
(Catalog# : 122843, Cas# :
909910-43-6
)
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/
AM251
(Catalog# : 122842, Cas# :
183232-66-8
)
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 3
AZD2858
(Catalog# : 122838, Cas# :
486424-20-8
)
AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, inhibits tau phosphoryl
Adjudin
(Catalog# : 122824, Cas# :
252025-52-8
)
Adjudin is a drug which is under development as a potential non-hormonal male contrac
AdipoRon
(Catalog# : 122822, Cas# :
924416-43-3
)
AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM)
Anamorelin
(Catalog# : 122407, Cas# :
249921-19-5
)
Anamorelin is a synthetic orally active ghrelin receptor agonist which is under devel
Atorvastatin sodium
(Catalog# : 122303, Cas# :
134523-01-6
)
Atorvastatin has the potential to ameliorate arsenic-induced vascular dysfunction and
Amrubicin
(Catalog# : 122211, Cas# :
110267-81-7
)
Amrubicin is a novel anthracycline derivative for treatment of bladder carcinoma.
AG 490
(Catalog# : 122210, Cas# :
134036-52-5
)
AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the fami
APD597
(Catalog# : 121804, Cas# :
897732-93-3
)
APD597 is a potent and selective GPR119 agonist, which is potential useful for the tr
AT-101
(Catalog# : 121434, Cas# :
90141-22-3
)
AT-101 is the orally bioavailable the R-(-) enantiomer of gossypol with potential ant
4-Aminobenzeneboronic Acid Hydrochloride
(Catalog# : 120701, Cas# :
80460-73-7
)
Coming soon!
Alendronate sodium trihydrate
(Catalog# : 120409, Cas# :
121268-17-5
)
Coming soon!
Ambroxol hydrochloride
(Catalog# : 120408, Cas# :
23828-92-4
)
Coming soon!
Actinomycin D
(Catalog# : 120110, Cas# :
50-76-0
)
Actinomycin D is the most significant member of actinomycines, which are a class of p
Altiratinib
(Catalog# : 120104, Cas# :
1345847-93-9
)
Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden i
AGI-5198
(Catalog# : 120103, Cas# :
1355326-35-0
)
AGI-5198 is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen
Acotiamide HCl
(Catalog# : 120102, Cas# :
773092-05-0
)
Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, up
A66
(Catalog# : 120101, Cas# :
1166227-08-2
)
A66 is a potent and specific p110 inhibitor with IC50 of 32 nM, >100 fold selectiv
AV-412
(Catalog# : 112101, Cas# :
451492-95-8
)
AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth fact
AR-12
(Catalog# : 111913, Cas# :
742112-33-0
)
AR-12 is an orally available, targeted anti-cancer agent that has been shown in pre-c
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Reparixin
(Catalog# : 25050, Cas# :
266359-83-5
)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
TAK-779
(Catalog# : 25049, Cas# :
229005-80-5
)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
BAY-1125976
(Catalog# : 25048, Cas# :
1402608-02-9
)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
Vimseltinib free base
(Catalog# : 25047, Cas# :
1628606-05-2
)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046, Cas# :
2128698-24-6
)
Cavosonstat
(Catalog# : 25045, Cas# :
1371587-51-7
)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
Ivospemin Hydrochloride
(Catalog# : 25044, Cas# :
259657-09-5
)
Ivospemin is an antineoplastic spermine analogue.
Survodutide
(Catalog# : 25043, Cas# :
2805997-46-8
)
XRD-0394
(Catalog# : 25042, Cas# :
2595308-10-2
)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
CC-90003
(Catalog# : 25041, Cas# :
1621999-82-3
)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E