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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyrimidines
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Name Index A
4-Amino-3-iodobenzoic acid
(Catalog# : 80311, Cas# :
2122-63-6
)
Coming soon!
ALPHA-BENZYL-4,6-O-BENZYLIDENE-MURAMIC ACID
(Catalog# : 80302, Cas# :
19229-57-3
)
Coming soon
AZD2014(Vistusertib)
(Catalog# : 71804, Cas# :
1009298-59-2
)
AZD2014is a potent (IC50 2.81 nM), selective (inactive against 220 other kinases) inh
AZD9496
(Catalog# : 71802, Cas# :
1639042-08-2
)
1) Sponsor:AstraZeneca2) Phase:Phase 13)AZD9496 is a novel, oral selective oestrogen
Alpelisib(BYL719)
(Catalog# : 62504, Cas# :
1217486-61-7
)
NVP-BYL719 is novel and specific PI3K inhibitor.NVP-BYL719 has displayed promising re
Apitolisib(GDC-0980,RG7422)
(Catalog# : 62503, Cas# :
1032754-93-0
)
Apitolisib(GDC-0980,RG7422) is a dual PI3K/mTOR inhibitor.GDC-0980 was potent across
Atazanavir
(Catalog# : 61005, Cas# :
198904-31-3
)
Atazanavir(BMS-232632) is an highly potent HIV-1 protease inhibitor.
Abexinostat
(Catalog# : 60702, Cas# :
783355-60-2
)
Abexinostat is a novel hydroxamate-based HDACi that showed broad spectrum anticancer
Axitinib
(Catalog# : 52771, Cas# :
319460-85-0
)
Axitinib, also known as AG013736, is an orally bioavailable tyrosine kinase inhibitor
AVL-292
(Catalog# : 52770, Cas# :
1202757-89-8
)
AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Bt
AT9283
(Catalog# : 52769, Cas# :
896466-04-9
)
AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and a
AT13387
(Catalog# : 52768, Cas# :
912999-49-6
)
AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displ
Asenapine maleate
(Catalog# : 52767, Cas# :
85650-56-2
)
Asenapine maleate(Org 5222 maleate) inhibits adrenergic receptor (1, 2A, 2B, 2C) with
AP26113
(Catalog# : 52766, Cas# :
1197958-12-5
)
AP26113 is a potent and selective active inhibitor of anaplastic lymphoma kinase(ALK)
AM095 free acid
(Catalog# : 52765, Cas# :
1228690-36-5
)
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 M for re
APY0201
(Catalog# : 52759, Cas# :
1232221-74-7
)
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM
AI-10-49
(Catalog# : 52757, Cas# :
1256094-72-0
)
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBF-SMM
AEE788
(Catalog# : 52750, Cas# :
497839-62-0
)
AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM an
Alogliptin Benzoate
(Catalog# : 52741, Cas# :
850649-62-6
)
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of &
AHAS inhibitor
(Catalog# : 52739, Cas# :
219793-45-0
)
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug
AZ20
(Catalog# : 52734, Cas# :
1233339-22-4
)
AZ20 is a potent and selective inhibitor of ATR with an IC50 of 5 nM; 8-fold selectiv
Afatinib
(Catalog# : 52719, Cas# :
850140-72-6
)
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R),
AICAR
(Catalog# : 52702, Cas# :
2627-69-2
)
AICAR (Acadesine), is an AMP-activated protein kinase activator, which is used for th
AMG-319
(Catalog# : 52026, Cas# :
1608125-21-8
)
AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K tha
AMG-925
(Catalog# : 51614, Cas# :
1401033-86-0
)
AMG925, Bulk in stock, contact us by email for detailed quotation.AMG-925 is a potent
ABT-737
(Catalog# : 52640, Cas# :
852808-04-9
)
ABT-737 is a BH3 mimetic inhibitor ofBcl-xL,Bcl-2andBcl-wwithEC50of 78.7 nM, 30.3 nM
AZD-7762
(Catalog# : 52638, Cas# :
860352-01-8
)
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM; equally potent
AZD1080
(Catalog# : 52626, Cas# :
612487-72-6
)
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor of GSK3 and GSK
A-674563
(Catalog# : 52617, Cas# :
552325-73-2
)
A-674563 is a potent selective Akt1 inhibitor with an IC50 of 14 nM; also shows inhib
Alisertib(MLN8237)
(Catalog# : 52587, Cas# :
1028486-01-2
)
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM; has >20
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag