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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Amino Acids
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Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Phenols
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Pyrimidines
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index P
PF-05231023
(Catalog# : 1811162, Cas# :
1037589-69-7
)
PF-05231023 is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and imp
PA-8
(Catalog# : 1810254, Cas# :
878437-15-1
)
A-8 is a small-molecule antagonist of the PAC1 receptor.
Pyronaridine Tetraphosphate
(Catalog# : 1810242, Cas# :
76748-86-2
)
Pyronaridine Tetraphosphate is an antimalarial agent, blocking B-hematin formation, i
PH-002
(Catalog# : 1810234, Cas# :
1311174-68-1
)
PH-002 is a novel inhibitor of apolipoprotein (apo) E4 intramolecular domain interact
Pemigatinib (INCB054828)
(Catalog# : 1810164, Cas# :
1513857-77-6
)
Pemigatinib (INCB054828) is an orally active, selectiveFGFRinhibitor withIC50s of 0.4
Pelitrexol
(Catalog# : 189131, Cas# :
446022-33-9
)
Pelitrexol is a GARFT inhibitor, and is also a water soluble antifolate with anti-pro
PCI-33380
(Catalog# : 18943, Cas# :
1022899-36-0
)
PCI-33380 was designed based on the ibrutinib scaffold and has been used in both cell
Perastine
(Catalog# : 187164, Cas# :
4960-10-5
)
Perastine is a biochemical.
PCO371
(Catalog# : 187125, Cas# :
1613373-33-3
)
PCO371 is a potent and selective PTHR1 agonist for the treatment of hypoparathyroidis
PQR530
(Catalog# : 18756, Cas# :
1927857-61-1
)
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor.
Pyrotinib
(Catalog# : 18731, Cas# :
1269662-73-8
)
Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor
PX20606 trans-isomer
(Catalog# : 186274, Cas# :
1268244-85-4
)
PX20606, also known as PX-102, is a FXR agonist.
PF-05180999
(Catalog# : 186153, Cas# :
1394033-54-5
)
PF-05180999 is a potent and selective PDE2a inhibitor (PDE2a IC50 = 0.001 μM, 2000-f
Pritelivir mesylate
(Catalog# : 186152, Cas# :
1428333-96-3
)
Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhib
Pridopidine
(Catalog# : 18673, Cas# :
346688-38-8
)
Pridopidine, also known as ACR16, is a dopamine stabilizer, which improves motor perf
Pamiparib
(Catalog# : 185233, Cas# :
1446261-44-4
)
Pamiparib is an antineoplastic drug candidate.Pamiparib (BGB-290) is an investigation
PAC 14028
(Catalog# : 185223, Cas# :
1005168-10-4
)
PAC 14028, also known as Asivatrep, is a vanilloid VR1 receptor (TRPV1) antagonist po
PE859
(Catalog# : 185157, Cas# :
1402727-29-0
)
PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66
PD 168 077
(Catalog# : 185156, Cas# :
190383-31-4
)
PD168077 is a dopamine D4 receptor agonist which has a facilitatory effect on memory
PF-06462894
(Catalog# : 185155, Cas# :
1622291-66-0
)
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM).
PF-06291874
(Catalog# : 185154, Cas# :
1393124-08-7
)
PF-06291874 is a glucagon receptor antagonist and potentially usefully for patients w
Poseltinib
(Catalog# : 185153, Cas# :
1353552-97-2
)
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
Pibrentasvir
(Catalog# : 185148, Cas# :
1353900-92-1
)
Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the trea
PP2 Analog
(Catalog# : 185147, Cas# :
309739-67-1
)
PP2 Analog is an analog of PP2 that acts as a protein trafficking modulator.
PP2
(Catalog# : 185146, Cas# :
172889-27-9
)
PP2, also known as AG 1879, is a substance that has frequently been used in cancer re
PP1
(Catalog# : 185145, Cas# :
172889-26-8
)
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor.
Pocapavir
(Catalog# : 185144, Cas# :
146949-21-5
)
Pocapavir, also known as SCH-48973 and V-073, is a potent, selective, antienterovirus
PSMA617 TFA
(Catalog# : 185143, Cas# :
1702967-37-0
)
PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to
Pyridostatin TFA salt
(Catalog# : 185142, Cas# :
1472611-44-1
)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
PF-06260933
(Catalog# : 18544, Cas# :
1811510-56-1
)
PF-06260933 is a potent and highly selective inhibitor of MAP4K4.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
HC-5404
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno