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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
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Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
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Name Index P
PI-3065
(Catalog# : 122908, Cas# :
955977-50-1
)
PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhib
PD 123319
(Catalog# : 122903, Cas# :
130663-39-7
)
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of
PNU-282987
(Catalog# : 122827, Cas# :
123464-89-1
)
PNU-282987 is a selective 7 nicotinic acetylcholine receptor(7 nAChR) agonist with Ki
PF-431396
(Catalog# : 122818, Cas# :
717906-29-1
)
PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK
Posaconazole
(Catalog# : 122815, Cas# :
171228-49-2
)
Posaconazole is a broad-spectrum, second generation, triazole compound with antifunga
PQ401
(Catalog# : 122806, Cas# :
196868-63-0
)
PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylur
Pardoprunox
(Catalog# : 122523, Cas# :
269718-84-5
)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
PKC-IN-1
(Catalog# : 122520, Cas# :
1046787-18-1
)
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM; compound example H6 fro
PF-04447943
(Catalog# : 122515, Cas# :
1082744-20-4
)
PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and
PD-0325901
(Catalog# : 122405, Cas# :
391210-10-9
)
PD-0325901 i a potent bioavailable and selective MEK inhibitor, which targets mitogen
P005672 hydrochloride
(Catalog# : 122302, Cas# :
1035979-44-2
)
P005672 hydrochloride is used for antibacterial/anti-inflammatory acne treatment.
Pirodavir
(Catalog# : 122216, Cas# :
124436-59-5
)
Pirodavir is the prototype of a novel class of broad-spectrum antipicornavirus compou
PD173074
(Catalog# : 122212, Cas# :
219580-11-7
)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
Pyroxamide
(Catalog# : 121802, Cas# :
382180-17-8
)
Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic propertie
PKI-402
(Catalog# : 121421, Cas# :
1173204-81-3
)
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K/// and mTOR with IC50
PHA-665752
(Catalog# : 121418, Cas# :
477575-56-7
)
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9
Pimavanserin
(Catalog# : 120809, Cas# :
706779-91-1
)
Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x
Pemetrexed disodium
(Catalog# : 120704, Cas# :
150399-23-8
)
Coming soon!
PX-478
(Catalog# : 111307, Cas# :
685847-78-3
)
PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potentia
Pardoprunox hydrochloride
(Catalog# : 111010, Cas# :
269718-83-4
)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
PD153035 Hcl
(Catalog# : 111003, Cas# :
183322-45-4
)
PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM an
PRT-060318
(Catalog# : 110904, Cas# :
1194961-19-7
)
PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach
PCI-27483
(Catalog# : 110401, Cas# :
871266-63-6
)
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VI
PSEUDOLARIC ACID B
(Catalog# : 110223, Cas# :
82508-31-4
)
Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempfer
PL-100
(Catalog# : 102616, Cas# :
612547-11-2
)
PL-100 is a novel HIV-1 protease inhibitor (PI) with a favorable cross-resistance pro
propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate
(Catalog# : 102302, Cas# :
1334513-02-8
)
Coming soon!
PF-562271 benzenesulfonate salt
(Catalog# : 101919, Cas# :
939791-38-5
)
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion
2-Pyrimidineacetonitrile (9CI)
(Catalog# : 101903, Cas# :
59566-45-9
)
Coming soon!
PF06447475
(Catalog# : 101601, Cas# :
1527473-33-1
)
PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 o
Pluripotin(SC-1)
(Catalog# : 100502, Cas# :
839707-37-8
)
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small mol
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag