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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
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Name Index T
TDZD-8
(Catalog# : 161009029, Cas# :
327036-89-5
)
TDZD-8 protects the brain against I/R injury by inhibiting GSK-3beta activity. TDZD-8
Tideglusib
(Catalog# : 9028, Cas# :
865854-05-3
)
Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusi
TWS-119
(Catalog# : 161009027, Cas# :
601514-19-6 (free base); 1507095-58-0 (2 TFA salt)
)
TWS119 could activate Wnt/-catenin pathway and up-regulate the expression of CD62L in
Triciribine
(Catalog# : 161009022, Cas# :
35943-35-2
)
Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, an
Tacrolimus
(Catalog# : 161009006, Cas# :
104987-11-3
)
It is also used in a topical preparation in the treatment of atopic dermatitis (eczem
TG100713
(Catalog# : 160926017, Cas# :
925705-73-3
)
TG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI
TG100-115
(Catalog# : 160926011, Cas# :
677297-51-7
)
TG100-115, inhibited PI3K and -(IC50 values of 83 and 235 nM, respectively), whereas
Taltirelin
(Catalog# : 16071029, Cas# :
103300-74-9
)
Taltirelin
TMP-195
(Catalog# : 16071020, Cas# :
1314891-22-9
)
TMP-195
TC-G 1008
(Catalog# : 16071003, Cas# :
1621175-65-2
)
TC-G 1008,
T-5224
(Catalog# : 16070909, Cas# :
530141-72-1
)
T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates live
Tanespimycin
(Catalog# : 16070805, Cas# :
75747-14-7
)
Tanespimycin, also known as 17-AAG, is an orally bioavailable, small-molecule inhibit
Taladegib
(Catalog# : 121414, Cas# :
1258861-20-9
)
Taladegib is a potent Hedgehog inhibitor with potential anticancer activity, which in
Tivantinib
(Catalog# : 16070802, Cas# :
905854-02-6
)
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with
TAK-580 (MLN2480)
(Catalog# : 16062203, Cas# :
1096708-71-2
)
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-R
trovirdine
(Catalog# : 16060302, Cas# :
149488-17-5
)
trovirdine
Taprenepag(CP-544326)
(Catalog# : 652601, Cas# :
752187-80-7
)
Taprenepag is the active metabolite of PF-04217329.
Trofinetide
(Catalog# : 032406, Cas# :
853400-76-7
)
Trofinetide is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant.
Tyrosine kinase inhibitor
(Catalog# : 030302, Cas# :
1021950-26-4
)
Coming soon!
Tenalisib
(Catalog# : 012009, Cas# :
1639417-53-0 or 1693773-94-2
)
Tenalisib is a potent and selective dual PI3K/ inhibitor that inhibited growth of B-c
Tanzisertib
(Catalog# : 011903, Cas# :
899805-25-5
)
Tanzisertib is a potent, selective, and orally active JNK inhibitor with potential an
TH-302
(Catalog# : 011812, Cas# :
918633-87-1
)
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumo
Tradipitant
(Catalog# : 011810, Cas# :
622370-35-8
)
Tradipitant is the 2nd generation neurokinin-1 receptor antagonist, which showed acti
TGN 255
(Catalog# : 011114, Cas# :
871576-03-3
)
Coming soon!
TAK-733
(Catalog# : 010813, Cas# :
1035555-63-5
)
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of
Tiotropium Bromide
(Catalog# : 010502, Cas# :
136310-93-5
)
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blo
Tetrabenazine
(Catalog# : 010501, Cas# :
58-46-8
)
Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorde
Tiotropium Bromide
(Catalog# : 010439, Cas# :
139404-48-1
)
Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic
TAS-102
(Catalog# : 010437, Cas# :
733030-01-8
)
TAS-102 is an investigational drug candidate for metastatic colorectal cancer.
Tapentadol hydrochloride
(Catalog# : 010407, Cas# :
175591-09-0
)
Tapentadol Hcl is a centrally acting oral analgesic with opioid and adrenergic activi
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.
Phylloflavan
(Catalog# : 24155, Cas# :
98570-83-3
)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW
VK-28
(Catalog# : 24154, Cas# :
312611-92-0
)
VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced
SR-11302
(Catalog# : 24153, Cas# :
160162-42-5
)
SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor.
AKOS037652256
(Catalog# : 24152, Cas# :
2171065-77-1
)
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associat
ML353
(Catalog# : 24151, Cas# :
2990506-75-5
)
ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM).
MIF098
(Catalog# : 24150, Cas# :
1208448-95-6
)
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.
TM5441sodium
(Catalog# : 24149, Cas# :
2319722-53-5
)
TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhi
RGT-018
(Catalog# : 24148, Cas# :
2794934-49-7
)
RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects.