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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
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Indoles and Oxindoles
Iodos
Nitro Compounds
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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订购信息
联系我们
公司简介
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产品名字索引 T
醋酸曲普瑞林
(Catalog# : 18592, Cas# :
140194-24-7
)
醋酸曲普瑞林是一种促性腺激素释放激素激动剂(GnRH激动剂),用作
Tropifexor
(Catalog# : 18591, Cas# :
1383816-29-2
)
Tropifexor, 也称为LJN452, 是一种用于治疗胆静性肝病和非酒精性脂肪
THZ531
(Catalog# : 184172, Cas# :
1702809-17-3
)
THZ531是一种共价CDK12和CDK13共价抑制剂。环素依赖性激酶12和13 (CDK
托格列净
(Catalog# : 184311, Cas# :
903565-83-3
)
托格列净,也称为CSG452,是一种高效、高选择性的SGLT2抑制剂,在
TPX-0005
(Catalog# : 18423, Cas# :
1802220-02-5
)
TPX-0005是一种Src/FAK/Janus激酶2 (JAK2)抑制剂。TPX-0005 + EGFR TKI抑制RTKs
tert-butyl ((1H-benzo[d][1,2,3]triazol-1-yl)methyl)carbamate
(Catalog# : 183214, Cas# :
305860-41-7
)
tert-butyl (1H-benzo[d][1,2,3]triazol-1-yl)methylcarbamate is a drug intermediate.
Timapiprant
(Catalog# : 1712152, Cas# :
851723-84-7
)
Timapiprant, also known as OC000459, is a potent, selective and orally active CRTH2 a
TUG-770
(Catalog# : 1791519, Cas# :
1402601-82-4
)
TUG-770是高度有效的游离脂肪酸受体1(FFA1/GPR40)治疗2型糖尿病的激动
TH-2120
(Catalog# : 179157, Cas# :
81686-22-8
)
TH-2120,也称为钠离子载体III是一个载体。离子载体适用于血钠活
Thiomyristoyl
(Catalog# : 1791113, Cas# :
1429749-41-6
)
Thiomyristoyl是一种强效和特异性的IC50为28nM的SIRT2抑制剂。IC50与目标
TC-O9311
(Catalog# : 179828, Cas# :
444932-31-4
)
TC-O9311是一种强效的GPR139激动剂(GPR139 在人体细胞CHO-K1表达中EC50
琥珀酸曲格列汀
(Catalog# : 179811, Cas# :
1029877-94-8
)
曲格列汀,也称为SYR472,是一种武田制药正在开发的治疗2型糖尿
TUG-891
(Catalog# : 1783014, Cas# :
1374516-07-0
)
TUG-891是一种有效且选择性的游离脂肪酸受体4(FFA4 / GPR120),它既显
TP-3654
(Catalog# : 178303, Cas# :
1361951-15-6
)
TP-3654是一种Pim-1和Pim-3激酶抑制剂,可用于治疗前列腺癌、急性髓
TAK1抑制剂
(Catalog# : 1791412, Cas# :
1326712-16-6
)
TAK1 inhibitor isis discontinued.TAK1抑制剂是一种有效的、相对选择性的
TPCA-1
(Catalog# : 17031308, Cas# :
507475-17-4
)
TPCA-1是一种有效的IKK-2抑制剂。TPCA-1也是种STAT3磷酸化的高效抑制
曲古柳菌素A
(Catalog# : 17031306, Cas# :
58880-19-6
)
曲古柳菌素A, 也称为TSA,是一种HDAC抑制剂. 在生长阶段开始时,TSA
噻替派
(Catalog# : 17031304, Cas# :
52-24-4
)
噻替派是一种多功能型、有机磷烷基化剂,是一种稳定的N,N',N'' -
Tirabrutinib游离 ( ONO-4059 )
(Catalog# : 17031303, Cas# :
1351636-18-4
)
Tirabrutinib,也被称为ONO- 4059,是在抑制剂中,一种强大的、具有口
TCS-OX2-29盐酸盐
(Catalog# : 17031302, Cas# :
1610882-30-8
)
TCS-OX2- 29或TCS OX2 29,也被称为TCSOX229和TCS - OX229,是一种选择性的
TX1-85-1
(Catalog# : 17030713, Cas# :
1603845-32-4
)
TX1-85-1是一种ErbB3抑制剂. TX2-121-1可能通过异位机制发挥Her3依赖性
Tipiracil HCl
(Catalog# : 17030710, Cas# :
183204-72-0
)
Tipiralacil,又称TPI,是胸腺嘧啶磷酸化酶抑制剂(TPI)。Tipiracil是TAS
Turofexorate isopropyl
(Catalog# : 17030707, Cas# :
629664-81-9
)
Turofexorate isopropyl,也被称为WAY- 362450和XL335,是一种高效、选择性
TWS-119
(Catalog# : 17030204, Cas# :
601514-19-6
)
TWS-119 是一种强有力的和糖原合酶选择性抑制剂激酶-3β(IC50 = 30 nM
Tenapanor HCl
(Catalog# : 17030113, Cas# :
1234365-97-9
)
Tenapanor, 也称为AZD-1722和RDX 5791, 是钠-质子(Na(+)/ H(+))交换器NHE3的抑
盐酸替罗非班
(Catalog# : 17030103, Cas# :
150915-40-5
)
替罗非班是一种抗血小板药物。它属于一种名为糖蛋白IIb / IIIa抑
TAS-109
(Catalog# : 17022810, Cas# :
135598-68-4
)
TAS-109, 也称为DFP-10917和CNDAC,是一种具有潜在抗肿瘤活性的核苷酸脱
TRX818
(Catalog# : 17022401, Cas# :
1256037-58-7
)
TRX-818是一种可口服的生物制剂,具有潜在的抗肿瘤活性和抗血管
乐可安
(Catalog# : 17021310, Cas# :
15421-84-8
)
乐可安是一种PDGF拮抗剂,可抑制PDGF生成胶质瘤细胞的增殖。
ONO-4059盐酸盐
(Catalog# : 17012103, Cas# :
1439901-97-9
)
ONO-4059是BTK的选择性和新型抑制剂,IC50为2.2 nm,ONO-4059与B细胞内的
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag