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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
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Name Index M
MDK1846
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846 is a potent ketohexokinase (KHK) inhibitor.
MMG-11
(Catalog# : 1932010, Cas# :
313254-94-3
)
MMG-11 is a potent and selective dual inhibitor of TLR2/1 and TLR2/6 signaling with l
ML221
(Catalog# : 19311, Cas# :
877636-42-5
)
ML221 is an antagonist of the apelin (APJ) receptor.
Melphalan flufenamide
(Catalog# : 192279, Cas# :
380449-51-4
)
Melphalan flufenamide, also known as Melflufen, J-1, or Prodrug J-1, is a melphalan p
ML184
(Catalog# : 192214, Cas# :
794572-10-4
)
CID2440433, also known as ML-184, is a potent synthetic agonist of GPR55 (EC50 = 0.26
Mitapivat
(Catalog# : 192191, Cas# :
1260075-17-9
)
Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase act
MK-3903
(Catalog# : 192183, Cas# :
1219737-12-8
)
MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM).
Myriocin
(Catalog# : 191283, Cas# :
35891-70-4
)
Myriocin, also known as antibiotic ISP-1 and thermozymocidin, is an atypical amino ac
MA242 TFA
(Catalog# : 191256, Cas# :
1049704-18-8
)
MA242 is a Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. MA242 dec
MIK665
(Catalog# : 191252, Cas# :
1799631-75-6
)
MIK665, also known as S 64315, is an inhibitor of induced myeloid leukemia cell diffe
MY 5445
(Catalog# : 191211, Cas# :
78351-75-4
)
MY 5445 is a potential platelet aggregation inhibitor.
MRS1706
(Catalog# : 19131, Cas# :
264622-53-9
)
MRS1706 is a selective adenosine A2B receptor inverse agonist with Ki values of 1.39,
MRS1177
(Catalog# : 1812296, Cas# :
183721-13-3
)
MRS1177 is a bioactive chemical.
MLN-4760
(Catalog# : 1812295, Cas# :
305335-31-3
)
MLN-4760 is an angiotensin-converting (ACE2) inhibitor. In huMNCs, MLN-4760-B detecte
MDK-8384
(Catalog# : 1812254, Cas# :
761438-38-4
)
MDK-8384, also known as ALK inhibitor 2, is a potent and selective ALK inhibitor.
Mavacamten
(Catalog# : 181255, Cas# :
1642288-47-8
)
Mavacamten, also known as SAR-439152 and MYK-461, is a myosin inhibitor potentially f
MK-2048
(Catalog# : 181251, Cas# :
869901-69-9
)
MK-2048 is a a second-generation HIV-1 integrase inhibitor.
ML 351
(Catalog# : 1811282, Cas# :
847163-28-4
)
ML 351 is a selective 12/15 LOX inhibitor that is active in vivo.
Maropitant
(Catalog# : 1811261, Cas# :
147116-67-4
)
Maropitan, also known as CJ 11972, is a neurokinin (NK1) receptor antagonist.
MBQ-167
(Catalog# : 181152, Cas# :
2097938-73-1
)
MBQ-167 is a potent, dual Rac/Cdc42 inhibitor with IC50 of 103/78 nM, respectively, i
MDK4882
(Catalog# : 1810301, Cas# :
94164-88-2
)
MDK4882 also known as PKM2 inhibitor or compound 3k, is a PKM2 inhibitor.
MU-380
(Catalog# : 181022, Cas# :
2109805-78-7
)
MU-380 is a potent and selective CHK1 inhibitor.
MRS1220
(Catalog# : 1810228, Cas# :
183721-15-5
)
MRS1220 is a potent and highly selective antagonist at the human A3 adenosine recepto
ME0328
(Catalog# : 1810174, Cas# :
1445251-22-8
)
ME0328 is an inhibitor of PARP-3 (IC50 = 0.89 μM).
MDK-4823
(Catalog# : 18962, Cas# :
1908414-82-3
)
MDK-4823, also known as LMPTP inhibitor1; is a potent inhibitor of the low-molecular-
MDK-4774
(Catalog# : 18961, Cas# :
2036044-77-4
)
MDK-4774, Porcupine-IN-1, is a Porcupine inhibitor.
ML-792
(Catalog# : 18941, Cas# :
1644342-14-2
)
ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular ass
ML327
(Catalog# : 187162, Cas# :
1883510-31-3
)
ML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin
MDK3627
(Catalog# : 187161, Cas# :
1421373-62-7
)
MDK3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR
MLN8054
(Catalog# : 18742, Cas# :
869363-13-3
)
MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highl
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!