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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
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Phenols
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index M
MI-503
(Catalog# : 178908, Cas# :
1857417-13-0
)
MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows p
Merestinib (LY2801653)
(Catalog# : 178905, Cas# :
1206799-15-6
)
Merestinib, also known as LY2801653, is a n orally available, small molecule inhibito
Miglustat hydrochloride
(Catalog# : 2017824, Cas# :
210110-90-0
)
Miglustat, also known as OGT 918, is a drug developed by Actelion and is used prima
MK-0812
(Catalog# : 2017080111, Cas# :
624733-88-6
)
MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (
MONASCIN
(Catalog# : 201708015, Cas# :
21516-68-7
)
It is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated
Mephenytoin
(Catalog# : 174161, Cas# :
50-12-4
)
Mephenytoin(CAS 50-12-4) is a hydantoin, used as an anticonvulsant.Mephenytoin(CAS 50
MT-DADMe-ImmA
(Catalog# : 703301, Cas# :
653592-04-2
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
MI-463
(Catalog# : 17031006, Cas# :
1628317-18-9
)
MI-463 is a potent inhibitor of Menin-MLL interaction with an IC50 value of 15.3 nM
ML-098
(Catalog# : 17030910, Cas# :
878978-76-8
)
ML-098, also known as CID-7345532, is an activator of the GTP-binding protein Rab7 (E
ML-265
(Catalog# : 17030804, Cas# :
1221186-53-3
)
ML265 is a potent PKM2 activator induces tetramerization and reduces tumor formation
MN-64
(Catalog# : 17030717, Cas# :
92831-11-3
)
MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, r
ML241
(Catalog# : 17030714, Cas# :
1346528-06-0
)
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase wi
ML348
(Catalog# : 17030712, Cas# :
899713-86-1
)
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor wit
MMAF (Monomethyl auristatin F)
(Catalog# : 17030611, Cas# :
745017-94-1
)
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of som
Merimepodib
(Catalog# : 17030308, Cas# :
198821-22-6
)
Merimepodib, also known as VX-497, is orally bioavailable IMPDH inhibitor, which inhi
ML-264
(Catalog# : 17030302, Cas# :
1550008-55-3
)
ML-264 is a Krppel-like factor 5 (KLF5) inhibitor That Potently Inhibits Growth of Co
MK-8245
(Catalog# : 17030109, Cas# :
1030612-90-8
)
MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and a
MLN-1117
(Catalog# : 17030101, Cas# :
1268454-23-4
)
Serabelisib (also known as MLN1117, INK1117, and TAK-117) is an orally bioavailable i
ML-281
(Catalog# : 17022811, Cas# :
1404437-62-2
)
ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nan
Maraviroc
(Catalog# : 17022804, Cas# :
376348-65-1
)
Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4
MMAE (Monomethyl auristatin E)
(Catalog# : 17022403, Cas# :
474645-27-7
)
MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Bec
Monastrol
(Catalog# : 17021322, Cas# :
329689-23-8
)
Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is
MS049
(Catalog# : 17021313, Cas# :
1502816-23-0
)
MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM
Miransertib(ARQ 092)
(Catalog# : 17021301, Cas# :
1313883-00-9
)
ARQ 092 is a novel, orally bioavailable and selective AKT pathway inhibitor exhibit
MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101, Cas# :
1399840-35-7
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
(Catalog# : 17011908, Cas# :
7752-54-7
)
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
ML-7
(Catalog# : 17011107, Cas# :
110448-33-4
)
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki
MX69
(Catalog# : 17011105, Cas# :
1005264-47-0
)
MX69 is a MDM2/XIAP inhibitor, used for cancer treatment.
MK-571 sodium salt
(Catalog# : 16123055, Cas# :
115104-28-4
)
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the bindin
Mizoribine
(Catalog# : 16123053, Cas# :
50924-49-7
)
Mizoribine,Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The co
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag