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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Phenols
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Custom Synthesis
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Name Index M
ML224
(Catalog# : 61116, Cas# :
1338824-21-7
)
ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimula
(±)-Methotrimeprazine D6
(Catalog# : 61114, Cas# :
1189805-51-3
)
()-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 d
Motolimod
(Catalog# : 6111017, Cas# :
926927-61-9
)
Motolimod
MCC950 sodium
(Catalog# : 6111014, Cas# :
256373-96-3
)
MCC950 (CP 456773) sodium is a potent, selective, small molecule inhibitor of NLRP3 w
MS023
(Catalog# : 6111012, Cas# :
1831110-54-3
)
MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC
MK-4101
(Catalog# : 6111008, Cas# :
935273-79-3
)
MK-4101 is a potent SMO Inhibitor of the Hedgehog PathwayMK-4101 is a potent SMO Inhi
ML346
(Catalog# : 611940, Cas# :
100872-83-1
)
ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
mTOR-IN-1
(Catalog# : 611820, Cas# :
1207358-59-5
)
mTOR-IN-1 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 1.5
Miltefosine
(Catalog# : 161009023, Cas# :
58066-85-6
)
Miltefosine targets cellular membranes, modulating cell membrane permeability, membra
1-METHYL-5-NITRO-1H-INDOLE
(Catalog# : 169701, Cas# :
29906-67-0
)
1-METHYL-5-NITRO-1H-INDOLE CAS#29906-67-0
Mubritinib
(Catalog# : 16071022, Cas# :
366017-09-6
)
Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under deve
MK-8245
(Catalog# : 16070814, Cas# :
1030612-87-3
)
MK-8245
MLN120B
(Catalog# : 16070813, Cas# :
783348-36-7
)
MLN120B
MS417
(Catalog# : 16070106, Cas# :
916489-36-6
)
MS417, also known as GTPL7512, is a potent and selective BRD4 inhibitor. MS417 inhibi
Molidustat (BAY85-3934)
(Catalog# : 16062901, Cas# :
1154025-82-6
)
Molidustat (BAY85-3934)
MK-8931 ( Verubecestat )
(Catalog# : 1662118, Cas# :
1286770-55-5
)
Verubecestat(MK-8931) is a small-molecule inhibitor of beta-secretase cleaving enzyme
Methyl 2,5-dimethylnicotinate
(Catalog# : 16062101, Cas# :
63820-72-4
)
Methyl 2,5-dimethylnicotinate
MDK-5220
(Catalog# : 16060603, Cas# :
1796565-52-0
)
MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excel
MK-5172
(Catalog# : 032514, Cas# :
1350514-68-9
)
Coming soon!
Mirodenafil
(Catalog# : 030904, Cas# :
862189-95-5
)
Coming soon!
MK-2866
(Catalog# : 030901, Cas# :
1202044-20-9
)
Coming soon!
MCC950
(Catalog# : 030101, Cas# :
210826-40-7
)
MCC950 is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM
MRE-269
(Catalog# : 020106, Cas# :
475085-57-5
)
MRE-269 is a long-acting and highly selective prostacyclin receptor agonist.
MSX-122
(Catalog# : 011906, Cas# :
897657-95-3
)
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic a
ME-143
(Catalog# : 011902, Cas# :
852536-39-1
)
ME -143 is a derivative of triphendiol and is a highly potent, pan acting ant-cancer.
MK-2206
(Catalog# : 011805, Cas# :
1032349-93-1
)
MK-2206 2Hcl is an orally bioavailable allosteric inhibitor of the serine/threonine p
MK-8033
(Catalog# : 011801, Cas# :
1001917-37-8
)
MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt
ML324
(Catalog# : 011301, Cas# :
1222800-79-4
)
ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
MK-1775
(Catalog# : 011110, Cas# :
955365-80-7
)
MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA
MK-2461
(Catalog# : 010806, Cas# :
917879-39-1
)
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the