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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Anti-infection
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Indoles and Oxindoles
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
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On Sale
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Name Index M
Mubritinib
(Catalog# : 16071022, Cas# :
366017-09-6
)
Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under deve
MK-8245
(Catalog# : 16070814, Cas# :
1030612-87-3
)
MK-8245
MLN120B
(Catalog# : 16070813, Cas# :
783348-36-7
)
MLN120B
MS417
(Catalog# : 16070106, Cas# :
916489-36-6
)
MS417, also known as GTPL7512, is a potent and selective BRD4 inhibitor. MS417 inhibi
Molidustat (BAY85-3934)
(Catalog# : 16062901, Cas# :
1154025-82-6
)
Molidustat (BAY85-3934)
MK-8931 ( Verubecestat )
(Catalog# : 1662118, Cas# :
1286770-55-5
)
Verubecestat(MK-8931) is a small-molecule inhibitor of beta-secretase cleaving enzyme
Methyl 2,5-dimethylnicotinate
(Catalog# : 16062101, Cas# :
63820-72-4
)
Methyl 2,5-dimethylnicotinate
MDK-5220
(Catalog# : 16060603, Cas# :
1796565-52-0
)
MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excel
MK-5172
(Catalog# : 032514, Cas# :
1350514-68-9
)
Coming soon!
Mirodenafil
(Catalog# : 030904, Cas# :
862189-95-5
)
Coming soon!
MK-2866
(Catalog# : 030901, Cas# :
1202044-20-9
)
Coming soon!
MCC950
(Catalog# : 030101, Cas# :
210826-40-7
)
MCC950 is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM
MRE-269
(Catalog# : 020106, Cas# :
475085-57-5
)
MRE-269 is a long-acting and highly selective prostacyclin receptor agonist.
MSX-122
(Catalog# : 011906, Cas# :
897657-95-3
)
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic a
ME-143
(Catalog# : 011902, Cas# :
852536-39-1
)
ME -143 is a derivative of triphendiol and is a highly potent, pan acting ant-cancer.
MK-2206
(Catalog# : 011805, Cas# :
1032349-93-1
)
MK-2206 2Hcl is an orally bioavailable allosteric inhibitor of the serine/threonine p
MK-8033
(Catalog# : 011801, Cas# :
1001917-37-8
)
MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt
ML324
(Catalog# : 011301, Cas# :
1222800-79-4
)
ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
MK-1775
(Catalog# : 011110, Cas# :
955365-80-7
)
MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA
MK-2461
(Catalog# : 010806, Cas# :
917879-39-1
)
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met.
Medetomidine hydrochloride
(Catalog# : 010606, Cas# :
86347-15-1
)
Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is use
MK-2048
(Catalog# : 010424, Cas# :
870005-19-9
)
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV i
MK7622
(Catalog# : 51627, Cas# :
1227923-29-6
)
MK-7622isused as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for t
MK-4827
(Catalog# : 123007, Cas# :
1038915-60-4
)
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with grea
MK-0752
(Catalog# : 122949, Cas# :
471905-41-6
)
MK-0752 is a moderately potent -secretase inhibitor, which reduces A40 production wit
MK8745
(Catalog# : 122819, Cas# :
885325-71-3
)
MK-8745 is a novel Aurora-A specific inhibitor. MK8745 induced apoptotic cell death i
MK 886
(Catalog# : 122217, Cas# :
118414-82-7
)
MK 886 is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenas
ML216
(Catalog# : 122101, Cas# :
1430213-30-1
)
ML216 is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing si
Masitinib
(Catalog# : 121508, Cas# :
790299-79-5
)
Masitinib is a novel inhibitor for Kit and PDGFR/ with IC50 of 200 nM and 540 nM/800
MK-5108
(Catalog# : 121504, Cas# :
1010085-13-8
)
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM; 220- and 190-
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag