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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
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Anilines
Boronic Acids
Bromides
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Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Phenols
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Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
Process Development
Ordering
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Name Index M
Medetomidine hydrochloride
(Catalog# : 010606, Cas# :
86347-15-1
)
Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is use
MK-2048
(Catalog# : 010424, Cas# :
870005-19-9
)
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV i
MK7622
(Catalog# : 51627, Cas# :
1227923-29-6
)
MK-7622isused as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for t
MK-4827
(Catalog# : 123007, Cas# :
1038915-60-4
)
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with grea
MK-0752
(Catalog# : 122949, Cas# :
471905-41-6
)
MK-0752 is a moderately potent -secretase inhibitor, which reduces A40 production wit
MK8745
(Catalog# : 122819, Cas# :
885325-71-3
)
MK-8745 is a novel Aurora-A specific inhibitor. MK8745 induced apoptotic cell death i
MK 886
(Catalog# : 122217, Cas# :
118414-82-7
)
MK 886 is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenas
ML216
(Catalog# : 122101, Cas# :
1430213-30-1
)
ML216 is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing si
Masitinib
(Catalog# : 121508, Cas# :
790299-79-5
)
Masitinib is a novel inhibitor for Kit and PDGFR/ with IC50 of 200 nM and 540 nM/800
MK-5108
(Catalog# : 121504, Cas# :
1010085-13-8
)
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM; 220- and 190-
Mandyphos SL-M004-1
(Catalog# : 121502, Cas# :
494227-37-1
)
Coming soon!
Marbofloxacin
(Catalog# : 121425, Cas# :
115550-35-1
)
Marbofloxacin is a potent antibiotic of which depends upon its inhibition of DNA-gyra
Micafungin sodium
(Catalog# : 120712, Cas# :
208538-73-2
)
Micafungin is an antifungal drug that belongs to the antifungal class of compounds kn
Memantine hydrochloride
(Catalog# : 120703, Cas# :
41100-52-1
)
Coming soon!
1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-ol
(Catalog# : 5112803, Cas# :
924909-16-0
)
1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-ol
MCB-613
(Catalog# : 111305, Cas# :
1162656-22-5
)
Coming soon!
MG-132
(Catalog# : 111303, Cas# :
133407-82-6
)
MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain w
Mocetinostat(MGCD0103)
(Catalog# : 111015, Cas# :
726169-73-9
)
Mocetinostat is an orally-bioavailable, spectrum-selective HDAC inhibitor. Mocetinost
MGCD-265-analog
(Catalog# : 111013, Cas# :
875337-44-3
)
MGCD-265-analog is a tyrosine kinase inhibitor that selectively targets MET and Axl.M
MDL 28170
(Catalog# : 102610, Cas# :
88191-84-8
)
MDL 28170 is a potent, cell-permeable, and selective inhibitor of calpain and catheps
MI-773
(Catalog# : 102207, Cas# :
1303607-60-4
)
MI-773 is an orally available spiro-oxindole HDM2 (human double minute 2) antagonist
MK-0822
(Catalog# : 101915, Cas# :
603139-19-1
)
MK-0822 is an inhibitor of cathepsin K with potential anti-osteoporotic activity. It
ML204
(Catalog# : 101204, Cas# :
5465-86-1
)
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion cha
methyl 2-formyl-1,3-thiazole-4-carboxylate
(Catalog# : 92215, Cas# :
921927-88-0
)
Coming soon!
5-(methoxycarbonyl)-1-tosyl-1Hpyrrol-3-yl-3-boronic acid
(Catalog# : 92213, Cas# :
916177-00-9
)
Coming soon!
2-Methyl-1-benzofuran-6-ol
(Catalog# : 92203, Cas# :
54584-24-6
)
Coming soon!
2-Methyl-1,3-oxazole-4-carboxylic acid
(Catalog# : 91828, Cas# :
23012-17-1
)
Coming soon!
methyl 2-((1R,3S)-3-amino-1-hydroxy-4-methylpentyl)thiazole-4-carboxylate
(Catalog# : 91809, Cas# :
1265905-21-2
)
Coming soon!
MK-5172 intermediate
(Catalog# : 91802, Cas# :
1206524-85-7
)
MK-5172(Grazoprevir) intermediate
Methyl (1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-
(Catalog# : 91801, Cas# :
1206524-84-6
)
MK-5172(Grazoprevir) intermediate
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the