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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Proteases
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PROTAC
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Anilines
Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Phenols
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Name Index M
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Name Index M
MDK-4823
(Catalog# : 18962, Cas# :
1908414-82-3
)
MDK-4823, also known as LMPTP inhibitor1; is a potent inhibitor of the low-molecular-
MDK-4774
(Catalog# : 18961, Cas# :
2036044-77-4
)
MDK-4774, Porcupine-IN-1, is a Porcupine inhibitor.
ML-792
(Catalog# : 18941, Cas# :
1644342-14-2
)
ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular ass
ML327
(Catalog# : 187162, Cas# :
1883510-31-3
)
ML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin
MDK3627
(Catalog# : 187161, Cas# :
1421373-62-7
)
MDK3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR
MLN8054
(Catalog# : 18742, Cas# :
869363-13-3
)
MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highl
MK-3207
(Catalog# : 185284, Cas# :
957118-49-9
)
MK-3207 is a potent and orally active calcitonin gene-related peptide receptor antago
MI-773
(Catalog# : 185251, Cas# :
1303607-07-9
)
MI-773 is a novel orally available MDM2 antagonist.
MDK-1699
(Catalog# : 184191, Cas# :
432001-69-9
)
MDK-1699, also known as Skp2 inhibitor C1 and SKPin C1, is a Skp2 inhibitor.
MDK-6149
(Catalog# : 184173, Cas# :
508186-14-9
)
MDK-6149, also known as ACSS2 Inhibitor or Ac-CoA Synthase Inhibitor I, is a Ac-CoA S
MDK-7933
(Catalog# : 184161, Cas# :
1417997-93-3
)
MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in c
MDK7526 HCl
(Catalog# : 184104, Cas# :
1448189-80-7
)
MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective pr
MRT68921
(Catalog# : 184103, Cas# :
1190379-70-4
)
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).
MRT68921 HCl
(Catalog# : 184102, Cas# :
2080306-21-2
)
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).
Mc-Val-Ala-PAB
(Catalog# : 184219, Cas# :
1870916-87-2
)
Mc-Val-Ala-PAB is a useful linker to make antibody-drug-conjugate (ADC) for targeting
ML335
(Catalog# : 184216, Cas# :
825658-06-8
)
ML335是一种有效的、选择性的TREK-1/2激活剂。ML335是一种用于OPRM1-O
ML365
(Catalog# : 184215, Cas# :
947914-18-3
)
ML365是一种有效的、选择性的K2P3.1 TASK-1通道阻滞剂。
MDK7229
(Catalog# : 184211, Cas# :
111797-22-9
)
MDK7229,也称为MD2- IN -1是MD2(髓样分化蛋白2)抑制剂。MDK7229锁住LPS-
MDK6574
(Catalog# : 18421, Cas# :
2102196-57-4
)
MDK6574, also known as FAA1 agonist-1, is a FAA1 agonist.
2-Methyl-7-azaindole
(Catalog# : 183131, Cas# :
23612-48-8
)
2-Methyl-7-azaindole is a drug Intermediate.
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde
(Catalog# : 1712293, Cas# :
1215310-75-0
)
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde是一种分子砌块。
MK-8617
(Catalog# : 1710163, Cas# :
1187990-87-9
)
MK-8617 is a potent, selective, orally bioavailabl Pan-Inhibitor of Hypoxia-Inducible
MSC2530818
(Catalog# : 1710135, Cas# :
1883423-59-3
)
MSC2530818 is a Potent, Selective, and Orally Bioavailable CDK8 Inhibitor with CDK8 I
MDK19922
(Catalog# : 1791512, Cas# :
132819-92-2
)
MDK19922, also known as NOD-IN-1 or Compound 4, is a Potent inhibitor of nucleotide-b
Mozavaptan free base
(Catalog# : 179154, Cas# :
137975-06-5
)
Mozavaptan, also known as OPC 31260, is a vasopressin receptor antagonist marketed by
ML-141
(Catalog# : 179152, Cas# :
71203-35-5
)
ML-141, also known as CID2950007, is a Cdc42 inhibitor (EC50 = 2.1 μM).
MDK30165
(Catalog# : 179138, Cas# :
2060530-16-5
)
MDK30165, also known as K-Ras(G12C) Inhibitor 6.
MMAD
(Catalog# : 20179132, Cas# :
203849-91-6
)
MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MM
ML-385
(Catalog# : 179119, Cas# :
846557-71-9
)
ML-385 is a potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 μM) . ML-385 selec
ML-277
(Catalog# : 179115, Cas# :
516480-79-8
)
ML-277, also known as Chk2 Inhibitor II, is a Chk2 (checkpoint kinase 2) inhibitor. B
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Reparixin
(Catalog# : 25050, Cas# :
266359-83-5
)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
TAK-779
(Catalog# : 25049, Cas# :
229005-80-5
)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
BAY-1125976
(Catalog# : 25048, Cas# :
1402608-02-9
)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
Vimseltinib free base
(Catalog# : 25047, Cas# :
1628606-05-2
)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046, Cas# :
2128698-24-6
)
Cavosonstat
(Catalog# : 25045, Cas# :
1371587-51-7
)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
Ivospemin Hydrochloride
(Catalog# : 25044, Cas# :
259657-09-5
)
Ivospemin is an antineoplastic spermine analogue.
Survodutide
(Catalog# : 25043, Cas# :
2805997-46-8
)
XRD-0394
(Catalog# : 25042, Cas# :
2595308-10-2
)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
CC-90003
(Catalog# : 25041, Cas# :
1621999-82-3
)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E