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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Pyridines
Pyrimidines
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Name Index M
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Name Index M
ML327
(Catalog# : 187162, Cas# :
1883510-31-3
)
ML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin
MDK3627
(Catalog# : 187161, Cas# :
1421373-62-7
)
MDK3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR
MLN8054
(Catalog# : 18742, Cas# :
869363-13-3
)
MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highl
MK-3207
(Catalog# : 185284, Cas# :
957118-49-9
)
MK-3207 is a potent and orally active calcitonin gene-related peptide receptor antago
MI-773
(Catalog# : 185251, Cas# :
1303607-07-9
)
MI-773 is a novel orally available MDM2 antagonist.
MDK-1699
(Catalog# : 184191, Cas# :
432001-69-9
)
MDK-1699, also known as Skp2 inhibitor C1 and SKPin C1, is a Skp2 inhibitor.
MDK-6149
(Catalog# : 184173, Cas# :
508186-14-9
)
MDK-6149, also known as ACSS2 Inhibitor or Ac-CoA Synthase Inhibitor I, is a Ac-CoA S
MDK-7933
(Catalog# : 184161, Cas# :
1417997-93-3
)
MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in c
MDK7526 HCl
(Catalog# : 184104, Cas# :
1448189-80-7
)
MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective pr
MRT68921
(Catalog# : 184103, Cas# :
1190379-70-4
)
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).
MRT68921 HCl
(Catalog# : 184102, Cas# :
2080306-21-2
)
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).
Mc-Val-Ala-PAB
(Catalog# : 184219, Cas# :
1870916-87-2
)
Mc-Val-Ala-PAB is a useful linker to make antibody-drug-conjugate (ADC) for targeting
ML335
(Catalog# : 184216, Cas# :
825658-06-8
)
ML335是一种有效的、选择性的TREK-1/2激活剂。ML335是一种用于OPRM1-O
ML365
(Catalog# : 184215, Cas# :
947914-18-3
)
ML365是一种有效的、选择性的K2P3.1 TASK-1通道阻滞剂。
MDK7229
(Catalog# : 184211, Cas# :
111797-22-9
)
MDK7229,也称为MD2- IN -1是MD2(髓样分化蛋白2)抑制剂。MDK7229锁住LPS-
MDK6574
(Catalog# : 18421, Cas# :
2102196-57-4
)
MDK6574, also known as FAA1 agonist-1, is a FAA1 agonist.
2-Methyl-7-azaindole
(Catalog# : 183131, Cas# :
23612-48-8
)
2-Methyl-7-azaindole is a drug Intermediate.
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde
(Catalog# : 1712293, Cas# :
1215310-75-0
)
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde是一种分子砌块。
MK-8617
(Catalog# : 1710163, Cas# :
1187990-87-9
)
MK-8617 is a potent, selective, orally bioavailabl Pan-Inhibitor of Hypoxia-Inducible
MSC2530818
(Catalog# : 1710135, Cas# :
1883423-59-3
)
MSC2530818 is a Potent, Selective, and Orally Bioavailable CDK8 Inhibitor with CDK8 I
MDK19922
(Catalog# : 1791512, Cas# :
132819-92-2
)
MDK19922, also known as NOD-IN-1 or Compound 4, is a Potent inhibitor of nucleotide-b
Mozavaptan free base
(Catalog# : 179154, Cas# :
137975-06-5
)
Mozavaptan, also known as OPC 31260, is a vasopressin receptor antagonist marketed by
ML-141
(Catalog# : 179152, Cas# :
71203-35-5
)
ML-141, also known as CID2950007, is a Cdc42 inhibitor (EC50 = 2.1 μM).
MDK30165
(Catalog# : 179138, Cas# :
2060530-16-5
)
MDK30165, also known as K-Ras(G12C) Inhibitor 6.
MMAD
(Catalog# : 20179132, Cas# :
203849-91-6
)
MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MM
ML-385
(Catalog# : 179119, Cas# :
846557-71-9
)
ML-385 is a potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 μM) . ML-385 selec
ML-277
(Catalog# : 179115, Cas# :
516480-79-8
)
ML-277, also known as Chk2 Inhibitor II, is a Chk2 (checkpoint kinase 2) inhibitor. B
MDK35833
(Catalog# : 179114, Cas# :
1016535-83-3
)
MDK35833, also known as Oct3/4-inducer-1, is a potent Oct3/4-inducer. MDK35833 can pr
ML241 HCl
(Catalog# : 179111, Cas# :
2070015-13-1
)
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase wi
ML364
(Catalog# : 179833, Cas# :
1991986-30-1
)
ML364 is a small molecule inhibitor of the deubiquitinase USP2 with potential antican
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002, Cas# :
2891709-58-1
)
HC-5404
(Catalog# : 25001, Cas# :
2247396-91-2
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
HC-5404-FU
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
CMP-5 2HCl
(Catalog# : 24161, Cas# :
2309409-79-6
)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
Wu-5
(Catalog# : 24160, Cas# :
2630378-05-9
)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
VU-29
(Catalog# : 24159, Cas# :
890764-36-0
)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
ML-202
(Catalog# : 24158, Cas# :
1221186-52-2
)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.
Phylloflavan
(Catalog# : 24155, Cas# :
98570-83-3
)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW