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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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On Sale
Intermediates
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Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
Process Development
Ordering
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Name Index N
NS-398 (NS398)
(Catalog# : 17011106, Cas# :
123653-11-2
)
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for hum
Netarsudil (AR-13324) 2HCl
(Catalog# : 1710901, Cas# :
1253952-02-1
)
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is cu
Naftifine
(Catalog# : 16122834, Cas# :
65472-88-0
)
Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis,
Nafamostat mesylate
(Catalog# : 16122833, Cas# :
82956-11-4
)
Nafamostat, also known as FUT-175, is a serine protease inhibitor and an anticoagulan
NSC697923
(Catalog# : 16122791, Cas# :
343351-67-7
)
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E
NVP-CGM097
(Catalog# : 16122789, Cas# :
1313363-54-0
)
NVP-CGM097 is a highly potent and selective MDM2 inhibitor. It binds to the p53 bindi
NSC228155
(Catalog# : 16122779, Cas# :
113104-25-9
)
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and mo
NQDI-1
(Catalog# : 16122772, Cas# :
175026-96-7
)
NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute
Nitroxoline
(Catalog# : 16122719, Cas# :
4008-48-4
)
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive
Napabucasin
(Catalog# : 16122708, Cas# :
83280-65-3
)
Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.Napabucas
Necrosulfonamide
(Catalog# : 6111508, Cas# :
1360614-48-7
)
Necrosulfonamide is a very specific and potent necrosis inhibitor and blocks mixed li
Necrostatin 2 S enantiomer
(Catalog# : 6111412, Cas# :
852391-20-9
)
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.Necrostatin 2 is a
Necrostatin 2 racemate
(Catalog# : 6111411, Cas# :
852391-15-2
)
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.Necrostatin 2 is a
NBI-74330
(Catalog# : 6111112, Cas# :
855527-92-3
)
NBI-74330 is a small molecule antagonist for CXCR3, NBI-74330 demonstrates potent inh
Nastorazepide
(Catalog# : 6111110, Cas# :
209219-38-5
)
Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative
NU6300
(Catalog# : 611923, Cas# :
2070015-09-5
)
NU6300 is a non-covalent ATP-competitive CDK2 inhibitor (IC50 = 0.16 mM). NU6300
NU 7026
(Catalog# : 6118017, Cas# :
154447-35-5
)
NU 7026 is a novel and potential inhibitor of the DNA repair enzyme DNA-dependent pro
NMS-859
(Catalog# : 161014001, Cas# :
1449236-96-7
)
NMS-859 is a potent and specific small molecule covalent inhibitor of the ATPase VCP/
NCT-501
(Catalog# : 16071414, Cas# :
1802088-50-1
)
NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize rea
Naquotinib
(Catalog# : 16071107, Cas# :
448232-80-1
)
Naquotinib, also known as ASP8273, is an orally available, irreversible, third-genera
Necrostatin 2
(Catalog# : 16070914, Cas# :
852391-19-6
)
Necrostatin 2
Navitoclax (ABT-263)
(Catalog# : 16070102, Cas# :
923564-51-6
)
Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecul
NSC5844
(Catalog# : 16060601, Cas# :
140926-75-6
)
NSC5844
NU2058
(Catalog# : 032515, Cas# :
161058-83-9
)
Coming soon!
NIBR189
(Catalog# : 012007, Cas# :
1599432-08-2
)
NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2
NS6180
(Catalog# : 011118, Cas# :
353262-04-1
)
NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents
NVP-ACC-789
(Catalog# : 010432, Cas# :
300842-64-2
)
Coming soon!
NVP-TNKS656
(Catalog# : 010408, Cas# :
1419949-20-4
)
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC5
Nelarabine
(Catalog# : 010404, Cas# :
121032-29-9
)
Nelarabine is a Nucleoside Metabolic Inhibitor. The mechanism of action of nelarabine
Nilotinib HCl hydrate
(Catalog# : 122901, Cas# :
923288-90-8
)
Nilotinib is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinas
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the