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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
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JAK/STAT
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Cytoskeletal Signaling
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Cas号索引 1
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Cas号索引 1
1196541-47-5 | GDC-0575
(Catalog# : 189272)
GDC-0575 (ARRY-575, RG7741)是一种有效的选择性CHK1抑制剂,IC50为1.2 nM。
1025821-33-3 | GSK-626616
(Catalog# : 188241)
GSK 626616是一种YAK3/DYRK3激酶抑制剂。它是一种潜在治疗化疗性贫血
1373423-53-0 | GSK-J4游离
(Catalog# : 187163)
GSK-J4是一种可渗透的、有效的选择性组蛋白去甲基化酶。
1015787-98-0 | Gefapixant
(Catalog# : 187122)
Gefapixant (MK-7264) 是一个口服的、P2X3 受体活性拮抗剂,其对人同源
1365970-03-1 | Glecaprevir
(Catalog# : 185311)
Glecaprevir,也称为ABT-493和A-1282576, 是一种有效治疗HCV的NS 3/4A抑制剂
1351761-44-8 | GNE-7915
(Catalog# : 18595)
GNE-7915是一种有效的LRRK2激酶抑制剂。
1654725-02-6 | GLPG1837
(Catalog# : 1842811)
GLPG-1837,又名ABBV-974,是一种新型的关于囊性纤维化跨膜电导校准
1416992-39-6 | GC376钠
(Catalog# : 184175)
GC376是一种3CLpro抑制剂(3C-样蛋白酶抑制剂)。
1243245-18-2 | GNF-6231
(Catalog# : 18494)
GNF-6231是一种有效的、具有口服活性的、选择性的Porcupine抑制剂,
1616392-22-3 | GSK-3326595
(Catalog# : 184316)
GSK-3326595,也被称为EPZ015938,是一种具有口服活性的、强效的、选
1252608-59-5 | GIBH-130
(Catalog# : 18428)
GIBH-130 is a neuroinflammation inhibitor.
1346546-69-7 | GSK872
(Catalog# : 17101621)
GSK872是一个受体相互作用蛋白激酶抑制剂(RIP3)。GSK872抑制TNF-α
1539314-06-1 | GSK2881078
(Catalog# : 1791316)
GSK-2881078是一种潜在的对癌症恶病质的治疗选择性雄激素受体调节
1459687-96-7 | GJ-103钠
(Catalog# : 1791116)
GJ103氯化钠是通过自动模拟通读复合物GJ072。
1459687-89-8 | GJ-103 游离酸
(Catalog# : 1791115)
GJ103游离酸是通过自动模拟通读复合物GJ072。化学诱导通读提前终
199657-29-9 | Givinostat HCl
(Catalog# : 17919)
Givinostat或gavinostat,又名ITF2357,是一个强有力的和口服活性的组蛋
1350462-55-3 | 阿那匹韦
(Catalog# : 1783018)
阿那匹韦,也称为MK5172,是一种被批准用于治疗丙型肝炎的药物。
1496581-76-0 | GNE-3511
(Catalog# : 1781006)
GNE-3511是一种具有选择性的双亮氨酸激酶(DLK,MAP3K12)抑制剂,在神经
1336960-13-4 | GSK2193874
(Catalog# : 178914)
GSK2193874被认定为一种选择性的、口服的TRPV4阻断剂。
1622848-92-3 | GSK2982772
(Catalog# : 178911)
GSK2982772是一种ATP竞争性的受体- 1(激酶)抑制剂,IC50值为1 nM。它有
1254036-77-5 | GSK2269557
(Catalog# : 2017883)
GSK2269557,也称为GSK-2269557, 是一种有效且选择性的PI3K抑制剂.。
1282514-88-8 | GDC-0326
(Catalog# : 2017881)
GDC-0326是一种有效且选择性的磷酸肌醇的α-同种型3-激酶抑制剂(PI
1007573-18-3 | GSK-1521498
(Catalog# : 20178215)
GSK-1521498是一种新型阿片受体拮抗剂。它已经被证明可以减弱奖励
1816331-63-1 | GSK321
(Catalog# : 2017821)
GSK321是一种有效的、选择性的IDH1突变抑制剂。GSK321对HT- 1080细胞内
1936428-93-1 | GNE-272
(Catalog# : 20178121)
GNE-272对CBP / EP300的溴域具有很强的选择性(CBP IC50 = 0.02 μM, EP300 IC5
156223-05-1 | GTS-21
(Catalog# : 16123016)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
1910124-24-1 | GSK6853 (GSK-6853)
(Catalog# : 16123015)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
1346547-00-9 | GSK583
(Catalog# : 16123014)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
1010411-21-8 | GSK369796 Dihydrochloride
(Catalog# : 16123013)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
1619994-68-1 | GSK2801
(Catalog# : 16123012)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag