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Cytoskeletal Signaling
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Deuterated
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
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Pyridines
Pyrimidines
Quinolines
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Cas号索引 1
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Cas号索引 1
116686-15-8 | FK 3311
(Catalog# : 60203)
FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent.
131740-09-5 | Flavopiridol(Alvocidib)
(Catalog# : 52310)
Flavopiridol HCl competes with ATP to inhibit CDKs includingCDK1,CDK2,CDK4andCDK6with
1206161-97-8 | Filgotinib
(Catalog# : 51612)
Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM
1260907-17-2 | GSK 525762A
(Catalog# : 171459)
133052-90-1 | GF-109203X
(Catalog# : L20356)
GF-109203X is a potent and highly selective PCK inhibitor, which inhibits PKC isozyme
1258292-64-6 | GDC-046
(Catalog# : L20342)
GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor for TYK2, JAK1
1831144-46-7 | GDC-0214
(Catalog# : c20341)
iJak-381 is a highly potent, selective, and inhalable Janus kinase-1 (JAK-1) inhibito
106740-09-4 | GYY4137
(Catalog# : L20339)
GYY4137 is a novel water-soluble and slow releasing H2S donor. Hydrogen sulfide (H2S)
1139889-93-2 | Golgicide A
(Catalog# : 20292)
Golgicide A is a Potent, selective and reversible inhibitor of GBF1 ArfGEF. Golgicide
113852-41-8 | GS 0573 ( PMEDAP )
(Catalog# : 20275)
GS 0573 is an antiviral compound that has been studied for potential treatment of Fel
1953133-47-5 | Giredestrant
(Catalog# : 21248)
Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally ava
1652591-81-5 | GSK484 HCl
(Catalog# : 20111801)
GSK484 is a potent PAD-4 inhibitor (Protein-arginine deiminase type-4). GSK484 potent
1093070-16-6 | GRL0617
(Catalog# : 2071625)
GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro. G
1191237-69-0 | GS-441524
(Catalog# : 2071546)
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an
1622849-43-7 | GSK3145095
(Catalog# : 2071533)
GSK3145095 is a potent and orally active RIPK1 inhibitor (IC50 = 5 nM) with potential
1629063-81-5 | GNE-131
(Catalog# : 2071509)
GNE-131 is a Potent and Selective hNaV1.7 Inhibitor (Na V1.7 IC50 = 3 nM) for the Tre
1642581-63-2 | Glumetinib
(Catalog# : 203401)
Glumetinib, also known as SCC244, is a novel, potent and highly selective inhibitor o
1394121-05-1 | GNE-2861
(Catalog# : 111892)
GNE-2861 is a potent and exquisitely kinase-selective Group II PAK inhibitor (PAK4 Ki
1549811-53-1 | GSK-199
(Catalog# : 193293)
GSK199是一种选择性的PAD4抑制剂,在不含钙的情况下,其半峰抑制
1637770-13-8 | GS-626510
(Catalog# : 193221)
GS-626510是一种有效的BET家族溴域抑制剂。它的作用是针对BRD2/3/4和
1445879-21-9 | GSK2837808A
(Catalog# : 193194)
GSK2837808A是一种高效、选择性的乳酸脱氢酶A(LDHA)抑制剂(LDHA和LDHB的
1536200-31-3 | GNE-9605
(Catalog# : 192284)
GNE-9605是一种高效、选择性强、脑内渗透的氨基吡唑亮氨酸富集重
1227911-45-6 | GSK2334470
(Catalog# : 192224)
GSK2334470是一种有效的3-磷酸肌苷依赖性蛋白激酶(PDK1)抑制剂(IC50 ~
1032754-81-6 | GNE-477
(Catalog# : 192181)
GNE-477是一种有效的双PI3K/mTOR抑制剂。
1373422-53-7 | GSKJ1
(Catalog# : 191255)
GSKJ1是一种具有选择性和有效的组蛋白脱甲基酶抑制剂(GSK-J1)有重
1150701-66-8 | GSK1940029
(Catalog# : 1812102)
GSK1940029,又称SCD抑制剂1,是一种SCD抑制剂。GSK1940029能够潜在的局
1420367-28-7 | GSK2814338
(Catalog# : 181241)
GSK2814338,也称为Lp-PLA2 -IN-1,是一种Lp-PLA2抑制剂。
1642297-01-5 | GDC-0927
(Catalog# : 1811301)
GDC-0927, 也称为SRN-927,是下一代口服SERD,其作为一类SERD分子的潜
1923851-49-3 | GSK9311
(Catalog# : 1811233)
GSK9311是BRPF溴域高效高选择性抑制剂(BRPDF1 pIC50 = 6.0;BRPDF2 pIC50 = 4.3
1404456-53-6 | GSK-2830371
(Catalog# : 1810292)
GSK 2830371是WiP1抑制剂。它能抑制淋巴瘤和神经母细胞瘤模型中的细
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag