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Epigenetics
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Angiogenesis
Apoptosis
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Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
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Metabolism
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Proteases
Immunology & Inflammation
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others
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Antibody-drug Conjugate/ADC Related
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Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1007573-18-3 | GSK-1521498
(Catalog# : 20178215)
GSK-1521498是一种新型阿片受体拮抗剂。它已经被证明可以减弱奖励
1816331-63-1 | GSK321
(Catalog# : 2017821)
GSK321是一种有效的、选择性的IDH1突变抑制剂。GSK321对HT- 1080细胞内
1936428-93-1 | GNE-272
(Catalog# : 20178121)
GNE-272对CBP / EP300的溴域具有很强的选择性(CBP IC50 = 0.02 μM, EP300 IC5
156223-05-1 | GTS-21
(Catalog# : 16123016)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
1910124-24-1 | GSK6853 (GSK-6853)
(Catalog# : 16123015)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
1346547-00-9 | GSK583
(Catalog# : 16123014)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
1010411-21-8 | GSK369796 Dihydrochloride
(Catalog# : 16123013)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
1619994-68-1 | GSK2801
(Catalog# : 16123012)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
1224887-10-8 | GSK-2256098
(Catalog# : 16123011)
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with
1014691-61-2 | GSK0660
(Catalog# : 16123009)
GSK0660 is a selective PPAR antagonist. GSK0660 differentially regulated 273 transcri
133053-19-7 | Go6983
(Catalog# : 16123008)
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective
1362154-70-8 | GNE-617
(Catalog# : 16123007)
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC5
1628260-79-6 | GLPG-1690(ziritaxestat)
(Catalog# : 16123005)
GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential a
1434048-34-6 | GDC-0853
(Catalog# : 16123004)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
1095173-27-5 | Glasdegib (PF-04449913)
(Catalog# : 16122787)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
136194-77-9 | Go6976
(Catalog# : 16122723)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
1254036-66-2 | GSK2292767
(Catalog# : 16122702)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
1474110-21-8 | GSK2981278
(Catalog# : 6111521)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
1616391-87-7 | GSK-591
(Catalog# : 6111009)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
1254036-71-9 | GSK2269557 free base
(Catalog# : 611826)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
1047635-80-2 | GSK2141795 (hydrochloride)
(Catalog# : 611807)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
1432913-36-4 | GX-674
(Catalog# : 1681201)
GX-674 is an aryl sulfonamide class of antagonists that inhibits Nav1.7.Nav (voltage-
1382979-44-3 | GDC-0084
(Catalog# : 16071405)
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor w
1254053-43-4 | Gilteritinib
(Catalog# : 16071108)
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed po
186452-09-5 | GPI-1046
(Catalog# : 16071027)
GPI-1046
1346607-05-3 | GSK621
(Catalog# : 16070905)
GSK621 is a specific and potentAMPKactivator.
1300031-49-5 | GSK1210151A
(Catalog# : 16070808)
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks rec
1453848-26-4 | GDC-0994
(Catalog# : 16062801)
GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular sig
117928-94-6 | GLYX 13
(Catalog# : 011809)
Coming soon!
1168091-68-6 | GDC-0623
(Catalog# : 010811)
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2375779-31-8 | GP130 modulator-1
(Catalog# : 25062)
GP130 modulator-1 (compound A33) 是一种GP130信号通路调节剂。GP130 modulato
877459-36-4 | TGN 073
(Catalog# : 25061)
TGN 073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. The rats
2257492-95-6 | OPN expression inhibitor 1
(Catalog# : 25060)
OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor
3036109-10-8 | SDU-071
(Catalog# : 25059)
SDU-071 is a potent and orally active inhibitor of BRD4-p53 inhibitor. SDU-071 suppre
2644662-83-7 | BBC0403
(Catalog# : 25058)
BBC0403 is a selective BRD2 inhibitor. BBC0403 inhibits the progression of osteoarthr
694488-83-0 | MFI8
(Catalog# : 25057)
MFI8 is a Mitochondrial Fusion Inhibitor
146255-66-5 | DHPG
(Catalog# : 25056)
DHPG, also known as (RS)-3,5-DHPG, is a selective agonist for group I metabotropic gl
2413020-56-9 | BAY-593 free base
(Catalog# : 25055)
BAY-593 is an orally active inhibitor of geranylgeranyltransferase-I (GGTase-I) that
188425-85-6 | Boscalid
(Catalog# : 25054)
Boscalid is a broad spectrum fungicide used in agriculture to protect crops from fung
690681-65-3 | SABA1
(Catalog# : 25053)
SABA1 is an antibacterial agent against Pseudomonas aeruginosa and Escherichia coli.