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抑制剂/受体激动剂
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Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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Stem Cells & Wnt
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Metabolism
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others
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Bromides
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Catalysts
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Deuterated
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Indoles and Oxindoles
Iodos
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1229236-86-5 | Gandotinib(LY2784544)
(Catalog# : 91415)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
1365888-06-7 | GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
1380672-07-0 | G007-LK
(Catalog# : 62908)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
1207360-89-1 | GDC-0349
(Catalog# : 62702)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
103766-25-2 | Gimeracil
(Catalog# : 52804)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
1260907-17-2 | GSK 525762A
(Catalog# : 52745)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
1218942-37-0 | GKT137831
(Catalog# : 52627)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
1372540-25-4 | GSK2636771
(Catalog# : 52618)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
1047634-63-8 | GSK2110183
(Catalog# : 52584)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
1262618-39-2 | GS967
(Catalog# : 52216)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
1346574-57-9 | GSK126
(Catalog# : 52208)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
1346572-63-1 | GSK503
(Catalog# : 51805)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
1394076-92-6 | GNE-317
(Catalog# : 52215)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
188591-46-0 | GSK3787
(Catalog# : 52018)
GSK3787 is as a selective and irreversible antagonist ofPPARwithpIC50of 6.6, with no
1337532-29-2 | GSK 2656157
(Catalog# : 52019)
GSK2656157 is an ATP-competitive and highly selective inhibitor ofPERKwithIC50of 0.9
1644645-32-8 | HTL14242
(Catalog# : 24115)
HTL14242 is a mGlu5 Negative Allosteric Modulator. Metabotropic glutamate receptors (
1441057-15-3 | 2(1H)-Pyridinone, 5,6-dihydro-4-(4-methylphenyl)-3-(2H-tetrazol-5-yl)-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-, (6S)-
(Catalog# : 20430)
182318-78-1 | 4-hydroxybiphenyl-4-carboxamide
(Catalog# : 20404)
173933-40-9 | HISPOLON(P)
(Catalog# : 210201)
1415792-84-5 | HMPL-523
(Catalog# : 20123101)
HMPL-523 is a novel, highly selective and potent small molecule oral inhibitor target
1628291-95-1 | HC-070
(Catalog# : 206104)
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepres
155558-32-0 (HCl) | Hydroxyfasudil HCl
(Catalog# : 204610)
Hydroxyfasudil, aslo known as HA1100, is a cell-permeable hydroxylated metabolite of
1009734-33-1 | HZ-1157
(Catalog# : 19182)
HZ-1157是一种丙肝病毒(HCV)抑制剂,对HCV NS3/4A蛋白酶有抑制作用。
173528-92-2 | HMN-154
(Catalog# : 184122)
HMN-154是一种苯磺胺的抗癌剂。HMN-154通过剂量依赖性的方式抑制NF
1420290-99-8 | HJC0152
(Catalog# : 1710133)
HJC0152是对人的头部和颈部鳞状细胞癌(鳞癌)的信号转导与转录
1702259-66-2 | H3B-6527
(Catalog# : 179822)
H3B-6527是一个强有力的口服活性分子抑制剂,具有潜在的抗肿瘤活
130964-39-5 | H-89盐酸盐
(Catalog# : 178815)
H-89是一种特殊的腺苷酸环酶抑制剂(DDA),是一种循环的氨依赖性蛋
1448867-41-1 | HDM201
(Catalog# : 2017872)
HDM201是一种口服生物利用率在人的同源基因(HDM2)抑制剂。具有潜在
1802181-20-9 | HM-61713 (BI-1482694)
(Catalog# : 17022709)
BI-1482694是布鲁顿酪氨酸激酶(BTK)的一种有效的小分子抑制剂。
1158279-20-9 | HLCL-61 HCl
(Catalog# : 16122819)
HLCL-61 is a potent and selective PRMT5 inhibitor for treatment of acute myeloid leuk
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!