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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1075236-89-3 | Gepotidacin
(Catalog# : 010610)
Gepotidacin is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel a
1217457-86-7 | GGTI-298
(Catalog# : 010609)
GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential
1443461-21-9 | GSK2838232
(Catalog# : 122924)
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed f
1431368-48-7 | GSK-LSD1 2HCl
(Catalog# : 122505)
Coming soon!
1346704-33-3 | GSK343
(Catalog# : 122402)
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold se
1032823-75-8 | GSK1292263
(Catalog# : 121430)
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabet
1089283-49-7 | GSK1904529A
(Catalog# : 121428)
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, &
1229236-86-5 | Gandotinib(LY2784544)
(Catalog# : 91415)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
1365888-06-7 | GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
1380672-07-0 | G007-LK
(Catalog# : 62908)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
1207360-89-1 | GDC-0349
(Catalog# : 62702)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
103766-25-2 | Gimeracil
(Catalog# : 52804)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
1260907-17-2 | GSK 525762A
(Catalog# : 52745)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
1218942-37-0 | GKT137831
(Catalog# : 52627)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
1372540-25-4 | GSK2636771
(Catalog# : 52618)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
1047634-63-8 | GSK2110183
(Catalog# : 52584)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
1262618-39-2 | GS967
(Catalog# : 52216)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
1346574-57-9 | GSK126
(Catalog# : 52208)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
1346572-63-1 | GSK503
(Catalog# : 51805)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
1394076-92-6 | GNE-317
(Catalog# : 52215)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
188591-46-0 | GSK3787
(Catalog# : 52018)
GSK3787 is as a selective and irreversible antagonist ofPPARwithpIC50of 6.6, with no
1337532-29-2 | GSK 2656157
(Catalog# : 52019)
GSK2656157 is an ATP-competitive and highly selective inhibitor ofPERKwithIC50of 0.9
1095539-84-6 | 6-溴-1,3-二甲基-1H-吲唑
(Catalog# : 25036)
1644645-32-8 | HTL14242
(Catalog# : 24115)
HTL14242 is a mGlu5 Negative Allosteric Modulator. Metabotropic glutamate receptors (
1441057-15-3 | 2(1H)-Pyridinone, 5,6-dihydro-4-(4-methylphenyl)-3-(2H-tetrazol-5-yl)-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-, (6S)-
(Catalog# : 20430)
182318-78-1 | 4-hydroxybiphenyl-4-carboxamide
(Catalog# : 20404)
173933-40-9 | HISPOLON(P)
(Catalog# : 210201)
1415792-84-5 | HMPL-523
(Catalog# : 20123101)
HMPL-523 is a novel, highly selective and potent small molecule oral inhibitor target
1628291-95-1 | HC-070
(Catalog# : 206104)
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepres
155558-32-0 (HCl) | Hydroxyfasudil HCl
(Catalog# : 204610)
Hydroxyfasudil, aslo known as HA1100, is a cell-permeable hydroxylated metabolite of
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2375779-31-8 | GP130 modulator-1
(Catalog# : 25062)
GP130 modulator-1 (compound A33) 是一种GP130信号通路调节剂。GP130 modulato
877459-36-4 | TGN 073
(Catalog# : 25061)
TGN 073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. The rats
2257492-95-6 | OPN expression inhibitor 1
(Catalog# : 25060)
OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor
3036109-10-8 | SDU-071
(Catalog# : 25059)
SDU-071 is a potent and orally active inhibitor of BRD4-p53 inhibitor. SDU-071 suppre
2644662-83-7 | BBC0403
(Catalog# : 25058)
BBC0403 is a selective BRD2 inhibitor. BBC0403 inhibits the progression of osteoarthr
694488-83-0 | MFI8
(Catalog# : 25057)
MFI8 is a Mitochondrial Fusion Inhibitor
146255-66-5 | DHPG
(Catalog# : 25056)
DHPG, also known as (RS)-3,5-DHPG, is a selective agonist for group I metabotropic gl
2413020-56-9 | BAY-593 free base
(Catalog# : 25055)
BAY-593 is an orally active inhibitor of geranylgeranyltransferase-I (GGTase-I) that
188425-85-6 | Boscalid
(Catalog# : 25054)
Boscalid is a broad spectrum fungicide used in agriculture to protect crops from fung
690681-65-3 | SABA1
(Catalog# : 25053)
SABA1 is an antibacterial agent against Pseudomonas aeruginosa and Escherichia coli.