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Cytoskeletal Signaling
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others
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1404380-58-0 | JTE-151
(Catalog# : 20594)
1627902-21-9 | JNJ-54175446
(Catalog# : 20534)
JNJ-54175446 is a potent and selective P2X7 Receptor Antagonist. JNJ-54175446 is pote
1638611-48-9 | JC124
(Catalog# : 20495)
JC124 is a NLRP3 Inflammasome Inhibitor.
188791-09-5 | JTE-607 HCl
(Catalog# : 20479)
JTE-607, also known as TO-207, is a cytokine production inhibitor potentially for the
1309784-09-5 | JTE-051
(Catalog# : 20458)
JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK), suppress
1380392-05-1 | JMS-17-2
(Catalog# : 2071624)
JMS-17-2 is a potent and selective antagonist of CX3CR1.
1443235-95-7 | JAK3-IN-2
(Catalog# : 2071551)
JAK3-IN-2 is a potent and highly selective JAK3 inhibitor.
1572510-42-9 | JNJ-632
(Catalog# : 2071507)
JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with
1408064-71-0 | JNK-IN-7
(Catalog# : 2061305)
JNK-IN-7 is a relatively selective JNKs inhibitor(IC50= 1.54/1.99/0.75 for JNK1/2/3);
1408064-71-0 | JNK-IN-7
(Catalog# : 2061305)
1597402-27-1 | JPH203 HCl ( Nanvuranlat )
(Catalog# : 18381)
JPH203,也称为KYT- 0353,是一个强有力的和选择性(l型氨基酸转运蛋白
1142363-52-7 | JNJ-40346527
(Catalog# : 1711221)
JNJ-40346527是一种小分子和口服抑制剂,可用于促结肠菌素- 1受体(
1254977-87-1 | JNJ-42153605
(Catalog# : 1791311)
JNJ-42153605是一种强效的选择性mGlu2受体PAM可接受的药代动力学在啮
1346528-51-5 | JNJ-42165279(2HCl salt)
(Catalog# : 1783012)
JNJ-42165279具有良好的ADME和药效学特性,可以证明其在大鼠的大脑
1346528-52-6 | JNJ-42165279(mono HCl salt)
(Catalog# : 1783011)
JNJ-42165279(mono HCl salt)是一种强力的选择性脂肪酸酰胺水解酶(FAAH)抑
1913252-04-6 | JQ-EZ-05
(Catalog# : 2017871)
JQ-EZ-05也称为JQEZ5, 是一种生物活性化学药品。
1410880-22-6 | JNK-IN-8
(Catalog# : 16123027)
JNK-IN-8, also known as JNK Inhibitor XVI, is a selective JNK inhibitor that inhibits
1802326-66-4 | JNJ 63533054
(Catalog# : 16123026)
JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain an
1346528-50-4 | JNJ-42165279
(Catalog# : 16123025)
JNJ-42165279 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor. J
1037592-40-7 | JPH203(KYT-0353)
(Catalog# : 6112701)
JPH203(also known as KYT-0353) is a potent and selective LAT1 selective ( L-type amin
1805787-93-2 | JAK3-IN-1
(Catalog# : 6111506)
JAK3-IN-1 is a potent JAK3 inhibitor with IC50 of 4.8 nM, also inhibits JAK1 (IC50 =
1268524-70-4 | (+)-JQ1
(Catalog# : 16070105)
(+)-JQ1 is a BET potent BET bromodomain Inhibitor. Bromodomain and extra terminal dom
1193383-09-3 | JNJ-42041935
(Catalog# : 031401)
JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and
1639422-97-1 | JH-VIII-157-02
(Catalog# : 62103)
JH-VIII-157-02, a structural analogue of alectinib, is potent against the G1202R muta
1700693-08-8 | JH-II-127
(Catalog# : 012010)
JH-II-127 is a potent and selective inhibitor of both wild-type and G2019S mutant LRR
1127498-03-6 | JNJ 40411813
(Catalog# : 122939)
JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2
1210004-12-8 | JZL195
(Catalog# : 111007)
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and
1094873-14-9 | JNJ-31020028
(Catalog# : 100903)
JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropep
1146963-51-0 | J-147
(Catalog# : 52505)
J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) w
199596-05-9 | JIB-04
(Catalog# : 52225)
JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230, 34
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag