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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Phenols
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Pyridines
Pyrimidines
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Name Index S
Sapitinib(AZD8931)
(Catalog# : 60301, Cas# :
848942-61-0
)
AZD8931(Sapitinib)is a novel potent reversible small molecule epidermal growth factor
SU6656
(Catalog# : 52754, Cas# :
330161-87-0
)
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC
SBE13 Hydrochloride
(Catalog# : 52751, Cas# :
1052532-15-6
)
SBE13 Hcl is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora
SGI-1027
(Catalog# : 52737, Cas# :
1020149-73-8
)
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC5
SB225002
(Catalog# : 52714, Cas# :
182498-32-4
)
SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM;
SU9516
(Catalog# : 52579, Cas# :
377090-84-1
)
SU-9516 is a selective CDK2 inhibtor with IC50 of 22 nM; less potent for CDK1/CDK4(IC
SCH900776
(Catalog# : 52575, Cas# :
891494-63-6
)
SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kina
Selumetinib
(Catalog# : 52571, Cas# :
606143-52-6
)
Selumetinib (AZD6244; ARRY-142886) is a potent, highly selective MEK1 inhibitor with
Siramesine hydrochloride
(Catalog# : 52549, Cas# :
224177-60-0
)
Siramesine(Lu 28-179) Hcl is a selective sigma-2 receptor agonist, which has been sho
Siramesine
(Catalog# : 52548, Cas# :
147817-50-3
)
Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown t
S1RA
(Catalog# : 52546, Cas# :
878141-96-9
)
S1RA(E-52862) is a potent and selective sigma-1 receptor(1R, Ki=17 nM) antagonist, sh
SMI-4a
(Catalog# : 52537, Cas# :
438190-29-5
)
SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM fo
SKLB610
(Catalog# : 52536, Cas# :
1125780-41-7
)
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kin
StemRegenin 1
(Catalog# : 52531, Cas# :
1227633-49-9
)
StemRegenin 1(SR1) is an antagonist of the aryl hydrocarbon receptor.SR1 is the first
S0859
(Catalog# : 52507, Cas# :
1019331-10-2
)
S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recover
SRPIN340
(Catalog# : 52210, Cas# :
218156-96-8
)
SRPIN340 is a serine/arginine-rich protein kinase (SRPK)-specific inhibitor with an I
5S rRNA modificator
(Catalog# : 52243, Cas# :
1415238-77-5
)
5S rRNA modificator is a suitable electrophile for 2-hydroxyl acylation on structured
SB431542
(Catalog# : 52312, Cas# :
301836-41-9
)
SB431542 is a potent and selective inhibitor ofALK5withIC50of 94 nM, 100-fold more se
Salirasib
(Catalog# : 52106, Cas# :
162520-00-5
)
Salirasib(S-Farnesylthiosalicylic aci) is an S-farnesyl cysteine analog that interfer
SNS-032 ( BMS-387032 )
(Catalog# : 52105, Cas# :
345627-80-7
)
SNS-032 has firstly been described as a selective inhibitor ofCDK2withIC50of 48 nM an
SNS-314 Mesylate
(Catalog# : 52102, Cas# :
1057249-41-8
)
SNS-314 Mesylate is a potent and selective inhibitor ofAurora A,Aurora BandAurora Cwi
Semaxanib (SU5416)
(Catalog# : 51803, Cas# :
204005-46-9
)
Semaxanib (SU5416) is a potent and selectiveVEGFR(Flk-1/KDR) inhibitor withIC50of 1.2
SSR128129E
(Catalog# : 51608, Cas# :
848318-25-2
)
SSR128129E is an orally-active and allostericFGFR1inhibitor withIC50of 1.9 M, while n
SRT1720
(Catalog# : 52007, Cas# :
1001645-58-4
)
SRT1720 is a selectiveSIRT1activator withEC50of 0.16 M, but is >230-fold less pote
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the