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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Immunology & Inflammation
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Bromides
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Chiral Compounds
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Indoles and Oxindoles
Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
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Name Index S
SNX-2112
(Catalog# : 179815, Cas# :
908112-43-6
)
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergo
SU-1498
(Catalog# : 17984, Cas# :
168835-82-3
)
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEG
SF2523
(Catalog# : 17918, Cas# :
1174428-47-7
)
SF2523 is a highly selective and potent dual pan-PI3K/BRD4 inhibitor. SF2523 exhibits
SAR-20347
(Catalog# : 1781101, Cas# :
1450881-55-6
)
SAR-20347 is a potent dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2).
SB756050
(Catalog# : 20178811, Cas# :
447410-57-3
)
SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially fo
SAR-405
(Catalog# : 2017882, Cas# :
1523406-39-4
)
<span style="color:#34495E;font-family:" font-size:14px;background-color
Seco Rapamycin (sodium salt)
(Catalog# : 20177313, Cas# :
148554-65-8
)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not a
SU5402
(Catalog# : 174191, Cas# :
215543-92-3
)
SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibit
SAR-020106
(Catalog# : 17031004, Cas# :
1184843-57-9
)
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50
SH5-07
(Catalog# : 17031002, Cas# :
1456632-41-9
)
SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor, which induce antitumor ce
SUN11602
(Catalog# : 17030603, Cas# :
704869-38-5
)
SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of
Sardomozide HCl
(Catalog# : 17030306, Cas# :
138794-73-7
)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
Sacubitril sodium
(Catalog# : 17030108, Cas# :
149690-05-1
)
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being
SHP099 free base
(Catalog# : 17030107, Cas# :
1801747-42-1
)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
Semagacestat
(Catalog# : 17022802, Cas# :
425386-60-3
)
Semagacestat (LY450139) is a -secretase blocker for A42, A40 and A38 with IC50 of 10.
(S)-Tedizolid
(Catalog# : 17021402, Cas# :
1431699-67-0
)
Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency
STO-609
(Catalog# : 17021319, Cas# :
52029-86-4
)
STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kina
S49076
(Catalog# : 17021309, Cas# :
1265965-22-7
)
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 valu
SRT2183
(Catalog# : 17021306, Cas# :
1001908-89-9
)
SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1, currently being
SW044248
(Catalog# : 17011714, Cas# :
522650-83-5
)
SW044248 is a potent and selective Topoisomerase I inhibitor. SW044248 killed approxi
Sugammadex sodium
(Catalog# : 17011713, Cas# :
343306-79-6
)
Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent roc
Streptozocin
(Catalog# : 17011712, Cas# :
18883-66-4
)
Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacte
Sotagliflozin
(Catalog# : 17011711, Cas# :
1018899-04-1
)
Sotagliflozin, also known as LX4211, is an orally active and a dual SGLT1/SGLT2 inhib
Solithromycin
(Catalog# : 17011710, Cas# :
760981-83-7
)
Solithromycin, also known as CEM-101 and OP-1068, is a ketolide antibiotic undergoing
SMER28
(Catalog# : 17011709, Cas# :
307538-42-7
)
SMER28 is a small molecule modulator of autophagy, inducing autophagy independently o
SKF-38393 hydrochloride
(Catalog# : 17011707, Cas# :
62717-42-4
)
SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine
Sitafloxacin anhydrous
(Catalog# : 17011706, Cas# :
127254-12-0
)
Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone that is very ac
SHP099 HCl
(Catalog# : 17011704, Cas# :
1801747-11-4
)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
Shogaol (6-Shogaol)
(Catalog# : 17011703, Cas# :
555-66-8
)
Shogaol, also known as (6)-shogaol, is a pungent constituent of ginger similar in che
SGC707
(Catalog# : 17011702, Cas# :
1687736-54-4
)
SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginin
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the