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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
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Bromides
Carboxes
Catalysts
Chiral Compounds
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Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyrimidines
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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Custom Synthesis
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Name Index S
Selinexor free base
(Catalog# : 2051501, Cas# :
1393477-72-9 (free base)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Simurosertib
(Catalog# : 2041504, Cas# :
1330782-76-7
)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
SGC2085 free base
(Catalog# : 204609, Cas# :
1821908-48-8 (free base)
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
Segetalin B
(Catalog# : 204501, Cas# :
164991-89-3
)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
S26131
(Catalog# : 112592, Cas# :
296280-56-3
)
S26131 is a bioactive chemical.
SI113
(Catalog# : 111896, Cas# :
1392816-46-4
)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
3-[(1S)-1-aminoethyl]-8-chloro-2-phenyl-1,2-dihydroisoquinolin-1-one
(Catalog# : 196301, Cas# :
1350643-72-9
)
Selisistat ( EX-527 )
(Catalog# : 52001, Cas# :
49843-98-3
)
Selisistatwas the first identified potent and cell permeable SIRT1-specific inhibitor
ST-193
(Catalog# : 193261, Cas# :
489416-12-8
)
ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, La
SPL-707
(Catalog# : 193209, Cas# :
2195361-33-0
)
SPL-707 is the first selective and orally active SPPL2a inhibitor. It shows adequate
SHP394
(Catalog# : 193122, Cas# :
2055757-40-7
)
SHP394 is a potent and orally active SHP2 inhibitor (IC50 = 23 nM) with high lipophil
SGC-GAK-1
(Catalog# : 193113, Cas# :
2226517-76-4
)
SGC-GAK-1 is a potent and selective GAK kinase probe which targets the ATP-binding si
SU 5214
(Catalog# : 19314, Cas# :
186611-04-1
)
SU 5214 is a modulator of tyrosine kinase signal transduction.
Silvestrol
(Catalog# : 192278, Cas# :
697235-38-4
)
Silvestrol, a member of flavagline family of natural products from the genus of Aglai
Selpercatinib
(Catalog# : 192276, Cas# :
2152628-33-4
)
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties.
SM16
(Catalog# : 192215, Cas# :
614749-78-9
)
SM16 is a novel Type I TGF-β signaling inhibitor.
SB-674042
(Catalog# : 192151, Cas# :
483313-22-0
)
SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat is an antineoplastic drug candidate.
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat is a rotamase inhibitor and vascular endothelial growth factor (VEGF) pro
Saridegib
(Catalog# : 1812251, Cas# :
1037210-93-7
)
Saridegib, also known as IPI-926, is an orally bioavailable, cyclopamine-derived inhi
SAR260301
(Catalog# : 1812134, Cas# :
1260612-13-2
)
SAR260301 is potent and selective Class I phosphatidylinositol-3-kinase (PI3K)β spec
Sparsentan
(Catalog# : 1812132, Cas# :
254740-64-2
)
Sparsentan, also known as RE-021, PS433540 and DARA-a, is a Dual angiotensin II and e
SR-0987
(Catalog# : 1810263, Cas# :
303126-97-8
)
SR-0987 is a T cell-specific RORγ (RORγt) agonist. SR-0987 induces IL-17 expression
SGC-CBP30
(Catalog# : 1810244, Cas# :
1613695-14-9
)
SGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are ge
ST2825
(Catalog# : 1810243, Cas# :
894787-30-5
)
ST-2825 is MyD88 inhibitor. ST2825 provides neuroprotection after experimental trauma
Seletalisib
(Catalog# : 1810221, Cas# :
1362850-20-1
)
Seletalisib, also known as UCB-5857, is a potent and selective PI3 kinase inhibitor,
Simenepag
(Catalog# : 1810172, Cas# :
910562-15-1
)
Simenepag, also known as AGN-210676, is a small molecule prostaglandin E2 receptor ag
SR-17018
(Catalog# : 187166, Cas# :
2134602-45-0
)
SR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM.
SB-273005
(Catalog# : 186221, Cas# :
205678-31-5
)
SB-273005 is an inhibitor of integrin αvβ3.
STF-083010
(Catalog# : 185151, Cas# :
307543-71-1
)
STF-083010, also known as IRE1 Inhibitor I, is an inhibitor of the IRE1/XBP1 pathway.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.
Phylloflavan
(Catalog# : 24155, Cas# :
98570-83-3
)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW
VK-28
(Catalog# : 24154, Cas# :
312611-92-0
)
VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced
SR-11302
(Catalog# : 24153, Cas# :
160162-42-5
)
SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor.
AKOS037652256
(Catalog# : 24152, Cas# :
2171065-77-1
)
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associat
ML353
(Catalog# : 24151, Cas# :
2990506-75-5
)
ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM).
MIF098
(Catalog# : 24150, Cas# :
1208448-95-6
)
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.
TM5441sodium
(Catalog# : 24149, Cas# :
2319722-53-5
)
TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhi
RGT-018
(Catalog# : 24148, Cas# :
2794934-49-7
)
RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects.