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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Heterocycles
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Intermediates
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Custom Synthesis
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Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index S
SHMT-IN-2
(Catalog# : 20368, Cas# :
2102681-49-0
)
SHMT-IN-2 is a serine hydroxymethyltransferase (SHMT) inhibitor, potently inhibiting
SRI-011381
(Catalog# : L20355, Cas# :
1629138-41-5
)
SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer
SJ-172550
(Catalog# : L20353, Cas# :
431979-47-4
)
SJ-172550, also known as MDMX Inhibitor II, is an inhibitor of MDMX that disrupts MDM
SMN-C3
(Catalog# : 20344, Cas# :
1449597-34-5
)
SMN-C3is an orally active SMN2 splicing modulator and has the potential to treat spin
Stafia-1
(Catalog# : L20338, Cas# :
2582757-90-0
)
STM2457
(Catalog# : 20321, Cas# :
2499663-01-1
)
STM2457 is a highly potent and selective first-in-class catalytic inhibitor of METTL3
SRI-37330 HCl
(Catalog# : 20306, Cas# :
2322245-49-6
)
SRI-37330 hydrochloride is a novel inhibitor of TXNIP expression,and dose-dependently
SM-102
(Catalog# : 21252, Cas# :
2089251-47-6
)
SM-102 is an ionizable amino lipid that has been used in combination with other lipid
Seralutinib
(Catalog# : 21238, Cas# :
1619931-27-9
)
Seralutinib, also known as PK-10571 and GB002, is a Novel Inhaled Pdgfr Kinase Inhibi
Sonidegib (LDE-225)
(Catalog# : 21232, Cas# :
956697-53-3
)
Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable
SB-366791
(Catalog# : 21230, Cas# :
472981-92-3
)
SB-366791 is a potent and selective TRPV1 antagonist. SB-366791 inhibits glutamatergi
Scriptaid
(Catalog# : 21229, Cas# :
287383-59-9
)
Scriptaid, also known as GCK 1026, is a HDAC inhibitor. Scriptaid protects against tr
SNG-1153
(Catalog# : 21228, Cas# :
1446712-19-1
)
SNG-1153 is a modulator of estrogen receptor ER-alpha36.
Seltorexant
(Catalog# : 81498, Cas# :
1293281-49-8
)
Seltorexant, also known as JNJ-42847922 and MIN-202, is a selective orexin-2 receptor
(S)-3-(4,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)- 1,3,5-triazin-2-yl)-2,6,6-trifluorocyclohex-2-en-1-ol
(Catalog# : 20123103, Cas# :
2301974-60-5
)
Senaparib
(Catalog# : 20103002, Cas# :
1401682-78-7
)
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with
SAR 131675
(Catalog# : 2091901, Cas# :
1433953-83-3
)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
(1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one
(Catalog# : 2091205, Cas# :
528587-70-4
)
SJB2-043
(Catalog# : 2071609, Cas# :
63388-44-3
)
SJB2-043 is an inhibitor of USP1 target ID1 degradation in leukemic cells.
Spastazoline
(Catalog# : 2071521, Cas# :
2351882-11-4
)
Spastazoline is a novel inhibitor for aaa+ (atpases associated with diverse cellular
SB 225002
(Catalog# : 2071510, Cas# :
18298-32-4
)
SCH-23390 maleate
(Catalog# : 2071501, Cas# :
87134-87-0
)
SCH-23390 hydrochloride is a potent dopamine receptor antagonist (Ki values are 0.2 n
((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
(Catalog# : 202331, Cas# :
1369767-20-3
)
The bulk may be provided by custom synthesis.
(S)-4-(((1-Propyl-1H-imidazol-5-yl)methyl)sulfinyl)aniline
(Catalog# : 2062002, Cas# :
497223-38-8
)
SJ000291942
(Catalog# : 2051514, Cas# :
425613-09-8
)
SJ000291942 is a bone morphogenic protein (BMP) signaling activator.
Selinexor HCl
(Catalog# : 2051502, Cas# :
Unknown (HCl)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Selinexor free base
(Catalog# : 2051501, Cas# :
1393477-72-9 (free base)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Simurosertib
(Catalog# : 2041504, Cas# :
1330782-76-7
)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
SGC2085 free base
(Catalog# : 204609, Cas# :
1821908-48-8 (free base)
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
Segetalin B
(Catalog# : 204501, Cas# :
164991-89-3
)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag